| Compound ID |
Compound Name |
Compound Formula |
|
CP0468577
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-o-tolylnicotinamide
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|
C26H20FN5O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0095996
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide
Show/Hide
|
C25H16F3N5O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0510314
|
2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide
Show/Hide
|
C23H16F3N5O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0417725
|
4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)-2-(methylthio)pyrimidine-5-carboxamide
Show/Hide
|
C23H17F3N6O2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0468579
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2-(2-hydroxyethyl)phenyl)nicotinamide
Show/Hide
|
C27H22FN5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0468580
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-5-bromo-N-(2,4-difluorophenyl)nicotinamide
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|
C25H15BrF3N5O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0468576
|
2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(4-chlorophenyl)nicotinamide
Show/Hide
|
C23H17ClFN5O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0384833
|
2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-5-bromo-N-(2,4-difluorophenyl)nicotinamide
Show/Hide
|
C23H15BrF3N5O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0191525
|
4-(4-(7-(2-fluoro-4-(2-oxo-3-phenylimidazolidine-1-carboxamido)phenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-N-methylpiperazine-1-carboxamide
Show/Hide
|
C36H34FN7O4S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0402473
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)-6-methylnicotinamide
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|
C26H18F3N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0473815
|
N'-[4-[2-(1-ethylimidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-phenylpropanediamide
Show/Hide
|
C28H22FN5O4S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0457425
|
N'-[4-[2-[1-[2-(dimethylamino)ethyl]imidazole-4-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-phenylpropanediamide
Show/Hide
|
C30H27FN6O4S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0191521
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(2-fluorophenyl)-2-oxoimidazolidine-1-carboxamide
Show/Hide
|
C28H22F2N6O3S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0296656
|
N-[3-fluoro-4-[2-[1-(3-pyrrolidin-1-ylpropyl)imidazol-4-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C33H32FN7O3S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0504245
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-phenylnicotinamide
Show/Hide
|
C25H18FN5O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0253784
|
N-[3-fluoro-4-[2-[4-(piperazin-1-ylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C34H31FN6O3S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0490832
|
4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)pyrimidine-5-carboxamide
Show/Hide
|
C22H15F3N6O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0195511
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C27H21FN6O3S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0282510
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carbothioamide
Show/Hide
|
C27H21FN6O2S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0369461
|
N-[4-[2-(1-ethylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C28H23FN6O3S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0022314
|
1-N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide
Show/Hide
|
C29H24FN5O3S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0490708
|
N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-(4-fluorophenyl)propanediamide
Show/Hide
|
C27H21F2N5O3S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0509299
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2-chlorophenyl)nicotinamide
Show/Hide
|
C25H17ClFN5O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0253783
|
N-[[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamoyl]-2-phenylacetamide
Show/Hide
|
C26H20FN5O3S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0350474
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C28H23FN6O3S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0490706
|
N'-[3-fluoro-4-[2-(1-methylimidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
|
C27H20FN5O4S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0506489
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-(2-methoxyphenyl)propanediamide
Show/Hide
|
C28H24FN5O4S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0282509
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(2-methoxyphenyl)-2-oxoimidazolidine-1-carboxamide
Show/Hide
|
C29H25FN6O4S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0350270
|
N-[3-fluoro-4-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C27H21FN6O3S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0404718
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-(2-hydroxyphenyl)propanediamide
Show/Hide
|
C27H22FN5O4S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0137418
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide
Show/Hide
|
C28H22F2N6O3S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0289955
|
N'-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
|
C26H20FN5O3S
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0313455
|
1-N'-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide
Show/Hide
|
C28H22FN5O3S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0493069
|
N-[3-fluoro-4-[2-[4-[[methyl-[2-(4-methylpiperazin-1-yl)ethyl]amino]methyl]phenyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C38H40FN7O3S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0253734
|
N-[3-fluoro-4-[2-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C35H33FN6O3S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0396898
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-(2-fluorophenyl)propanediamide
Show/Hide
|
C27H21F2N5O3S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0296610
|
N-[3-fluoro-4-[2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C29H26FN5O3S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0473814
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-methyl-N'-phenylpropanediamide
Show/Hide
|
C28H24FN5O3S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0242512
|
N-[4-[2-[1-[2-(dimethylamino)ethyl]imidazol-4-yl]thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C30H28FN7O3S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0468578
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(5-fluoropyridin-2-yl)nicotinamide
Show/Hide
|
C24H16F2N6O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0282279
|
N-[3-fluoro-4-[2-[1-(2-pyrrolidin-1-ylethyl)imidazol-4-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C32H30FN7O3S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0310895
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C28H22FN5O3S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0396897
|
N'-[3-fluoro-4-[2-(1-methylimidazole-2-carbonyl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
|
C27H20FN5O4S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0533326
|
2-(4-(7-(2-fluoro-4-(3-oxo-3-(phenylamino)propanamido)phenoxy)thieno[3,2-b]pyridine-2-carbonyl)-1H-imidazol-1-yl)acetic acid
Show/Hide
|
C28H20FN5O6S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0091889
|
3-(3-fluoro-4-{[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C26H20FN5O2S2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0399926
|
1-N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-1-N'-(2-fluorophenyl)cyclopropane-1,1-dicarboxamide
Show/Hide
|
C29H23F2N5O3S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0253787
|
N-[3-fluoro-4-[2-(1-propan-2-ylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C30H26FN5O3S
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0534044
|
N'-[3-fluoro-4-[2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
|
C27H23FN4O4S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0297743
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N'-methyl-N'-phenylpropanediamide
Show/Hide
|
C27H22FN5O3S
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
|
CP0235561
|
(S)-N-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C30H29FN6O4S
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0495715
|
N-cyclohexyl-N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]propanediamide
Show/Hide
|
C27H28FN5O3S
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0534043
|
N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-(3-fluorophenyl)propanediamide
Show/Hide
|
C27H21F2N5O3S
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0514829
|
3-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)pyrazine-2-carboxamide
Show/Hide
|
C24H15F3N6O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0506315
|
(R)-N1-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-phenylmalonamide
Show/Hide
|
C29H28FN5O4S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0191524
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-3-methyl-2-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C29H24FN5O3S
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0372252
|
3-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)pyrazine-2-carboxamide
Show/Hide
|
C22H15F3N6O2
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0376373
|
4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-(4-fluorophenyl)butanamide
Show/Hide
|
C27H20F5N5O2S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0457426
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-[2-(trifluoromethyl)phenyl]propanediamide
Show/Hide
|
C28H21F4N5O3S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0158203
|
4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-phenylbutanamide
Show/Hide
|
C27H21F4N5O2S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0372253
|
4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)-2-(dimethylamino)pyrimidine-5-carboxamide
Show/Hide
|
C24H20F3N7O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0376375
|
4,4,4-trifluoro-N-(4-fluorophenyl)-3-(4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)butanamide
Show/Hide
|
C27H21F4N5O2S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0509300
|
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(4-fluorophenyl)-N-methylnicotinamide
Show/Hide
|
C26H19F2N5O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0164602
|
US9133183, Compound A
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|
C24H20FN7O3
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0218987
|
N-[4-[2-(3-acetylphenyl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C31H23FN4O4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0529940
|
N'-(3-fluoro-4-thieno[3,2-b]pyridin-7-yloxyphenyl)-N-phenylpropanediamide
Show/Hide
|
C22H16FN3O3S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0415835
|
4-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide
Show/Hide
|
C25H16F3N5O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0086600
|
N-[3-fluoro-4-[2-(1-propan-2-ylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-5-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C30H26FN5O3S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0402609
|
US9133183, Example 15
Show/Hide
|
C24H27N7O3
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0401944
|
3-anilino-N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-4,4,4-trifluorobutanamide
Show/Hide
|
C27H23F4N3O4
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0107000
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4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-3-(phenylamino)butanamide
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C27H21F4N5O2S
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1
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| 1 |
IC50 = 700 nM
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CP0045447
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4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-(2-methoxyphenyl)butanamide
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C28H23F4N5O3S
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1
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| 1 |
IC50 = 840 nM
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CP0246702
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US9133183, Example 29
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C24H27N7O3
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1
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| 1 |
IC50 = 898 nM
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CP0522011
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3-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenylamino)-4,4,4-trifluoro-N-phenylbutanamide
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C27H23F4N3O4
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1
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| 1 |
IC50 = 910 nM
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CP0291574
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1-N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N'-methyl-1-N'-phenylcyclopropane-1,1-dicarboxamide
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C29H24FN5O3S
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1
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| 1 |
IC50 = 1000 nM
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CP0253735
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N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-3-phenyl-2-sulfanylideneimidazolidine-1-carboxamide
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C27H21FN6O2S2
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1
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| 1 |
IC50 = 2000 nM
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CP0372251
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4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide
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C23H16F3N5O2
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1
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| 1 |
IC50 = 3500 nM
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CP0318113
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US9133183, Example 101
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C23H26ClFN6O5
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1
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| 1 |
IC50 = 4000 nM
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CP0038799
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N-[6-[4-[(4-anilino-1,1,1-trifluoro-4-oxobutan-2-yl)amino]-2-fluorophenoxy]pyrimidin-4-yl]pyrrolidine-1-carboxamide
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C25H24F4N6O3
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1
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| 1 |
IC50 > 5000 nM
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CP0401946
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N-[6-[2-fluoro-4-[[4,4,4-trifluoro-3-(4-fluoroanilino)butanoyl]amino]phenoxy]pyrimidin-4-yl]pyrrolidine-1-carboxamide
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C25H23F5N6O3
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1
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| 1 |
IC50 > 5000 nM
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CP0447489
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3-anilino-N-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-3-fluorophenyl]-4,4,4-trifluorobutanamide
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C26H22F4N4O4
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1
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| 1 |
IC50 > 5000 nM
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CP0223784
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US9133183, Example 1
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C23H25N7O4
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1
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| 1 |
IC50 > 5000 nM
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CP0338522
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US9133183, Example 18
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C22H25N7O4
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1
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| 1 |
IC50 > 5000 nM
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CP0338523
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US9133183, Example 42
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C21H23N7O3
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1
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| 1 |
IC50 > 5000 nM
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CP0402607
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US9133183, Example 91
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C24H24F2N6O4
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1
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| 1 |
IC50 > 5000 nM
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CP0468243
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US9133183, Example 90
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C20H24N6O4
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1
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| 1 |
IC50 > 5000 nM
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