Brief Information of the Compound and Protein
Compound Name
US9133183, Compound A
    Show/Hide
PubChem ID
CID: 90446506
Canonical SMILES
Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C3=O)c3ccc(F)cc3)nc2)ccn1
    Show/Hide
Compound Formula C24H20FN7O3
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 196 nM
   TI
   LI
   LO
   TS