General Information of the Compound
| Compound ID |
CP0164602
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| Compound Name |
US9133183, Compound A
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| Structure |
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| Formula |
C24H20FN7O3
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| Molecular Weight |
473.468
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| Canonical SMILES |
Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C3=O)c3ccc(F)cc3)nc2)ccn1
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| InChI |
InChI=1S/C24H20FN7O3/c1-30-15-16(13-28-30)21-12-19(8-9-26-21)35-20-6-7-22(27-14-20)29-23(33)32-11-10-31(24(32)34)18-4-2-17(25)3-5-18/h2-9,12-15H,10-11H2,1H3,(H,27,29,33)
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| InChIKey |
ADLRDDWBCKMWCY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01201, Hepatocyte growth factor receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2