General Information of the Compound
| Compound ID |
CP0468578
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| Compound Name |
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(5-fluoropyridin-2-yl)nicotinamide
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| Structure |
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| Formula |
C24H16F2N6O2
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| Molecular Weight |
458.428
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| Canonical SMILES |
Fc1ccc(NC(=O)c2cccnc2Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)nc1
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| InChI |
InChI=1S/C24H16F2N6O2/c25-14-3-6-21(30-13-14)32-24(33)17-2-1-9-27-23(17)31-15-4-5-20(18(26)12-15)34-19-8-11-29-22-16(19)7-10-28-22/h1-13H,(H,27,31)(H,28,29)(H,30,32,33)
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| InChIKey |
WDYSZPOSBKDWSY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound