General Information of the Compound
| Compound ID |
CP0514829
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
3-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)pyrazine-2-carboxamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C24H15F3N6O2
|
||||||||||||||||||
| Molecular Weight |
476.418
|
||||||||||||||||||
| Canonical SMILES |
Fc1ccc(NC(=O)c2nccnc2Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(F)c1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H15F3N6O2/c25-13-1-3-18(16(26)11-13)33-24(34)21-23(31-10-9-28-21)32-14-2-4-20(17(27)12-14)35-19-6-8-30-22-15(19)5-7-29-22/h1-12H,(H,29,30)(H,31,32)(H,33,34)
Show/Hide
|
||||||||||||||||||
| InChIKey |
MHWOEFYKEQWZSW-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound