Brief Information of the Compound and Protein
Compound Name
2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(4-chlorophenyl)nicotinamide
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PubChem ID
CID: 16223108
Canonical SMILES
Nc1cc(Oc2ccc(Nc3ncccc3C(=O)Nc3ccc(Cl)cc3)cc2F)ccn1
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Compound Formula C23H17ClFN5O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS