| Compound ID |
Compound Name |
Compound Formula |
|
CP0378524
|
1-((2R,3S)-4-(ethyl((S)-4-(4-fluorophenyl)butan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C27H38FN7O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0510752
|
1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C25H34FN7O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0522357
|
1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C24H32FN7O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0094763
|
1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C25H32FN7O2
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
|
CP0454110
|
1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(methyl)amino)-3-hydroxybutan-2-yl)urea
Show/Hide
|
C25H34FN7O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0522355
|
1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-(3-(4-fluorophenyl)propylamino)-3-hydroxybutan-2-yl)urea
Show/Hide
|
C24H32FN7O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0350082
|
1-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]-3-[3-(1-methylimidazol-2-yl)phenyl]urea
Show/Hide
|
C27H34FN5O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0510231
|
1-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-(1H-indazol-5-yl)urea
Show/Hide
|
C27H34FN5O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0446526
|
1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(methyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C23H30FN7O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0461158
|
1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C26H34FN7O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0464223
|
1-((2R,3S)-4-(cyclopropyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C25H32FN7O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0464752
|
1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C26H36FN7O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0560007
|
1-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C23H31N7O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0311018
|
1-[(1R,3S)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-1-hydroxy-4-methylpentan-3-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C27H36FN7O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0502276
|
1-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-(1H-indol-5-yl)urea
Show/Hide
|
C28H35FN4O
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0486804
|
1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(propyl)amino)-3-hydroxybutan-2-yl)urea
Show/Hide
|
C27H38FN7O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0513662
|
1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)urea
Show/Hide
|
C25H35N7O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0263954
|
1-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]-3-[3-methyl-5-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C26H34FN7O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0321344
|
[(1R,3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-3-[[3-(1-methyltetrazol-5-yl)phenyl]carbamoylamino]butyl] N-methylcarbamate
Show/Hide
|
C27H35FN8O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0344492
|
1-[(2R,4S)-4-(dimethylamino)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]-3-[3-ethyl-5-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C29H41FN8O
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0131315
|
1-((E)-1-Cyclooct-1-enyl)methyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide
Show/Hide
|
C30H37Cl2IN2O2
|
1
|
| 1 |
IC50 = 0.58 nM
|
|
|
|
CP0261761
|
1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(methylcarbamoyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C27H37FN6O3S
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0461157
|
1-((2R,3S)-4-(cyclopropyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C27H36FN7O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0464127
|
1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(methyl)amino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C26H34FN7O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0510750
|
1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C28H38FN7O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0490720
|
1-{(S)-1-[2-(3-Chloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C25H32ClN7O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0035824
|
1-[(1R,3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-1-hydroxyhexan-3-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C27H36FN7O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0263953
|
N-[(1S,3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-3-[[3-(1-methyltetrazol-5-yl)phenyl]carbamoylamino]butyl]acetamide
Show/Hide
|
C27H35FN8O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0263957
|
1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C24H30FN7O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0430908
|
1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-fluoro-phenyl)-ethyl]-4,4-dimethyl-piperidin-3-ylmethyl}-urea
Show/Hide
|
C27H36FN7O
|
1
|
| 1 |
IC50 = 0.63 nM
|
|
|
|
CP0036478
|
1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C28H36FN7O
|
2
|
| 1 |
IC50 = 0.7 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
|
CP0261763
|
1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(methylcarbamoyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C27H37FN6O3S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0230995
|
2-[3-[[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]carbamoylamino]-5-(1-methyltetrazol-5-yl)phenyl]-2-methylpropanoic acid
Show/Hide
|
C29H38FN7O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0425367
|
1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[4-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C28H36FN7O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0853758
|
1-(3a,7a-Dihydro-1H-indazol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
|
C27H34FN5O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0079622
|
1-(3,5-diacetylphenyl)-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
|
C27H34FN3O4
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0091215
|
1-[3,5-bis(1,3-thiazol-2-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
|
C29H32FN5O2S2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
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CP0059520
|
1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C26H35FN4O2S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0216414
|
1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(furan-2-ylmethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C30H38FN5O3S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
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CP0229221
|
1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-methoxyacetyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C28H38FN5O4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0344353
|
1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-fluoroethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C27H37F2N5O2S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0425375
|
1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[2-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C28H36FN7O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0464774
|
3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide
Show/Hide
|
C30H33FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0540909
|
3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide
Show/Hide
|
C29H30FN5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0846067
|
1-{6-[3-(3-Acetyl-phenyl)-ureido]-benzo[1,3]dioxol-5-ylmethyl}-4-(4-fluoro-benzyl)-1-methyl-piperidinium iodide
Show/Hide
|
C30H33FIN3O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0288319
|
1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-tetrahydro-2H-pyran-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C25H33FN4O3S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0064690
|
1-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]-3-[3-(1-methyltetrazol-5-yl)-5-propan-2-ylphenyl]urea
Show/Hide
|
C28H38FN7O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0263956
|
1-[3-ethyl-5-(1-methyltetrazol-5-yl)phenyl]-3-[3-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]propyl]urea
Show/Hide
|
C26H34FN7O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0350081
|
1-[(1R,3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-1-hydroxypentan-3-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C26H34FN7O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0529986
|
1-[3,5-Bis-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
|
C30H38FN11O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0918858
|
1-(3a,4-Dihydro-1H-benzoimidazol-5-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
|
C27H34FN5O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0136068
|
1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(ethylcarbamoyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C28H39FN6O3S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0091220
|
2-[3-[3-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]propylcarbamoylamino]-5-(1-methyltetrazol-5-yl)phenyl]-2-methylpropanoic acid
Show/Hide
|
C28H36FN7O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0516503
|
1-[3,5-bis(1,2-oxazol-3-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
|
C29H32FN5O4
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0500570
|
1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
|
C30H38FN3O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0918883
|
1-(1,2-Dihydro-pyridin-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
|
C25H35FN4O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0136071
|
1-(5-acetyl-4-methyl-thiazol-2-yl)-3-{(3S,4S)-4-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl}-urea
Show/Hide
|
C24H31FN4O4S2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0201664
|
1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-fluoroethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C27H37F2N5O2S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0229226
|
1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C31H42FN5O4S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0294093
|
1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C26H36FN5O2S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0344668
|
1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyanomethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
|
C27H35FN6O2S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0522351
|
1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C27H38FN7O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0496796
|
1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[3-(4-fluoro-phenyl)-propyl]-piperidin-3-yl}-urea
Show/Hide
|
C25H32FN7O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0035827
|
1-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]-3-[3-methyl-5-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C26H34FN7O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0064689
|
1-[(1R,3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-1-hydroxy-5-methylhexan-3-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
|
C28H38FN7O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0243337
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(S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3,5-diacetylphenyl)urea
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C26H32FN3O3
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1
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| 1 |
IC50 = 1.2 nM
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CP0344493
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1-[(2R,4S)-4-amino-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
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C25H33FN8O
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1
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| 1 |
IC50 = 1.2 nM
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CP0511856
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1-(1,3-benzothiazol-6-yl)-3-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
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C27H33FN4OS
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1
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| 1 |
IC50 = 1.2 nM
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CP0261818
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
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C27H36FN5O3S
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1
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| 1 |
IC50 = 1.3 nM
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CP0276230
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-methoxyacetyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
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C28H38FN5O4S
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1
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| 1 |
IC50 = 1.3 nM
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CP0321296
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyanomethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
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C27H35FN6O2S
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1
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| 1 |
IC50 = 1.3 nM
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CP0471247
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-oxopropyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
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C28H38FN5O3S
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1
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| 1 |
IC50 = 1.3 nM
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CP0378310
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4S)-1-[2-(4-fluoro-phenyl)-ethyl]-4-methyl-piperidin-3-ylmethyl}-urea
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C26H34FN7O
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1
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| 1 |
IC50 = 1.3 nM
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CP0035828
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1-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
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C25H32FN7O
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1
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| 1 |
IC50 = 1.3 nM
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CP0464647
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1-(3-chloro-2H-indazol-5-yl)-3-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
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C27H33ClFN5O
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1
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| 1 |
IC50 = 1.3 nM
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CP0269905
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-methylpiperidin-4-yl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C31H45FN6O2S
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1
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| 1 |
IC50 = 1.4 nM
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CP0311019
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1-[3,5-bis(triazol-1-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
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C27H32FN9O2
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1
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| 1 |
IC50 = 1.4 nM
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CP0425363
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-methyl-thiazol-2-yl)-urea
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C24H33FN4OS
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1
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| 1 |
IC50 = 1.4 nM
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CP0483570
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(2-methoxy-phenyl)-urea
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C27H36FN3O2
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1
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| 1 |
IC50 = 1.4 nM
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CP0495246
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(5-methyl-tetrazol-1-yl)-phenyl]-urea
Show/Hide
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C28H36FN7O
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1
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| 1 |
IC50 = 1.4 nM
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CP0261764
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(ethylcarbamoyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
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C28H39FN6O3S
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1
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| 1 |
IC50 = 1.5 nM
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CP0321268
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
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C31H42FN5O4S
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1
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| 1 |
IC50 = 1.5 nM
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CP0113627
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1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-methyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
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C25H32FN7O
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1
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| 1 |
IC50 = 1.5 nM
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CP0311020
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1-[(3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]hexan-3-yl]-3-[3-(2-hydroxypropan-2-yl)-5-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
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C30H42FN7O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0320718
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1-[3-acetyl-5-(1-methyltetrazol-5-yl)phenyl]-3-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
Show/Hide
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C27H34FN7O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0378836
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1-(3-Acetyl-4-fluoro-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
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C28H35F2N3O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0079957
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)acetyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H41FN6O3S
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1
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| 1 |
IC50 = 1.6 nM
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CP0136070
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)acetyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H41FN6O3S
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1
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| 1 |
IC50 = 1.6 nM
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CP0424939
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4R)-1-[2-(4-fluoro-phenyl)-ethyl]-4-isopropyl-piperidin-3-ylmethyl}-urea
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C28H38FN7O
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1
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| 1 |
IC50 = 1.6 nM
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CP0487178
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C25H32FN7O
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1
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| 1 |
IC50 = 1.6 nM
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CP0311021
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1-[3,5-di(pyrazol-1-yl)phenyl]-3-[3-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]propyl]urea
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C28H32FN7O
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1
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| 1 |
IC50 = 1.6 nM
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CP0439545
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-o-tolyl-urea
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C27H36FN3O
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1
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| 1 |
IC50 = 1.6 nM
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CP0869632
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1-(3a,7a-Dihydro-1H-indol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C28H35FN4O
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1
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| 1 |
IC50 = 1.6 nM
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CP0333903
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1-((2S,3R)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-tetrahydro-2H-pyran-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C25H33FN4O3S
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1
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| 1 |
IC50 = 1.7 nM
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CP0091218
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1-[3-bromo-5-(1-methyltetrazol-5-yl)phenyl]-3-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
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C25H31BrFN7O
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1
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| 1 |
IC50 = 1.7 nM
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CP0350084
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1-[3,5-di(pyrazol-1-yl)phenyl]-3-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
Show/Hide
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C29H34FN7O
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1
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| 1 |
IC50 = 1.7 nM
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CP0559359
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1-(2,3-dihydro-1H-indol-5-yl)-3-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
Show/Hide
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C28H37FN4O
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1
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| 1 |
IC50 = 1.7 nM
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CP0333901
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)-2-oxoethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H41FN6O3S
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1
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| 1 |
IC50 = 1.8 nM
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CP0486802
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1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
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C27H36FN7O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0485019
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1-{(S)-1-[2-(2,4-Difluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C25H31F2N7O
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1
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| 1 |
IC50 = 1.8 nM
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CP0230993
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1-[3-ethyl-5-(1-methyltetrazol-5-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
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C27H36FN7O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0321345
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1-[3-bromo-5-(1-methyltetrazol-5-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
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C25H31BrFN7O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0360138
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1-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]pentan-2-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
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C26H34FN7O
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1
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| 1 |
IC50 = 1.8 nM
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CP0494845
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(2-fluoro-phenyl)-urea
Show/Hide
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C26H33F2N3O
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1
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| 1 |
IC50 = 1.8 nM
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CP0942089
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1-(2,3-Dimethyl-3a,7a-dihydro-1H-indol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C30H39FN4O
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1
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| 1 |
IC50 = 1.8 nM
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CP0208643
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C27H36FN5O3S
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1
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| 1 |
IC50 = 1.9 nM
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CP0261819
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1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C25H34FN5O2S
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1
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| 1 |
IC50 = 1.9 nM
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CP0374503
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[3-(4-fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C26H34FN7O
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1
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| 1 |
IC50 = 1.9 nM
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CP0466950
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1-{(1R,2S)-2-[3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1H-indol-5-yl)-urea
Show/Hide
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C28H35FN4O
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1
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| 1 |
IC50 = 1.9 nM
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CP0502396
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1-methyl-1H-pyrazol-3-yl)-urea
Show/Hide
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C24H34FN5O
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1
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| 1 |
IC50 = 1.9 nM
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CP0505689
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-thiazol-2-yl-urea
Show/Hide
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C23H31FN4OS
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1
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| 1 |
IC50 = 1.9 nM
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CP0374646
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2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-3-(3-phenyl-ureido)-benzamide
Show/Hide
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C28H31FN4O2
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1
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| 1 |
IC50 = 2 nM
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CP0448904
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1-{6-[3-(3-Cyano-phenyl)-ureido]-benzo[1,3]dioxol-5-ylmethyl}-4-(4-fluoro-benzyl)-1-methyl-piperidinium; iodide
Show/Hide
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C29H30FIN4O3
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1
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| 1 |
IC50 = 2 nM
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CP0507585
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2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-[3-(3-methoxy-phenyl)-ureido]-N-methyl-benzamide
Show/Hide
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C29H33FN4O3
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1
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| 1 |
IC50 = 2 nM
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CP0548429
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3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide
Show/Hide
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C29H31FN4O3
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1
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| 1 |
IC50 = 2 nM
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CP0035037
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1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea
Show/Hide
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C28H36FN3O2
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1
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| 1 |
IC50 = 2 nM
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CP0079960
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-methylpiperidin-4-yl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C31H45FN6O2S
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1
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| 1 |
IC50 = 2 nM
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CP0079963
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-isobutyrylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H40FN5O3S
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1
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| 1 |
IC50 = 2 nM
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CP0261760
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-acetylpiperidin-4-yl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C32H45FN6O3S
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1
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| 1 |
IC50 = 2 nM
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CP0261762
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1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C26H36FN5O2S
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1
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| 1 |
IC50 = 2 nM
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CP0261820
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1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-tetrahydro-2H-pyran-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C25H33FN4O3S
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1
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| 1 |
IC50 = 2 nM
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CP0528131
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)-2-oxoethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H41FN6O3S
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1
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| 1 |
IC50 = 2 nM
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CP0081970
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1-[3,5-bis(triazol-1-yl)phenyl]-3-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
Show/Hide
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C27H32FN9O
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1
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| 1 |
IC50 = 2 nM
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CP0344496
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1-[3-ethyl-5-(1-methyltetrazol-5-yl)phenyl]-3-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
Show/Hide
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C27H36FN7O
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1
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| 1 |
IC50 = 2 nM
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CP0497886
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-methoxy-phenyl)-urea
Show/Hide
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C27H36FN3O2
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1
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| 1 |
IC50 = 2 nM
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CP0505699
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1-(3-Cyano-4-pyrazol-1-yl-cyclohexa-2,4-dienyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C30H37FN6O
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1
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| 1 |
IC50 = 2 nM
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CP0185536
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C25H34FN5O2S
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1
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| 1 |
IC50 = 2.1 nM
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CP0195692
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-propionylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C28H38FN5O3S
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1
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| 1 |
IC50 = 2.1 nM
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CP0464197
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-isobutyrylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H40FN5O3S
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1
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| 1 |
IC50 = 2.1 nM
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CP0185533
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-acetylpiperidin-4-yl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C32H45FN6O3S
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1
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| 1 |
IC50 = 2.2 nM
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CP0486928
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1-{(3S,4S)-4-Ethyl-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C27H36FN7O
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1
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| 1 |
IC50 = 2.2 nM
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CP0541496
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[3-(4-fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C26H34FN7O
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1
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| 1 |
IC50 = 2.2 nM
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CP0391070
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-[1,2,4]triazol-1-yl-phenyl)-urea
Show/Hide
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C28H35FN6O
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1
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| 1 |
IC50 = 2.2 nM
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CP0228253
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2-(6-Amino-benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide
Show/Hide
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C21H22Cl2N4OS2
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1
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| 1 |
IC50 = 2.3 nM
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CP0216412
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-hydroxyethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C27H38FN5O3S
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1
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| 1 |
IC50 = 2.3 nM
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CP0229223
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(3R,4R)-methyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate
Show/Hide
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C27H36FN5O4S
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1
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| 1 |
IC50 = 2.3 nM
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CP0377960
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1-{(1R,2S)-2-[3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1H-indazol-5-yl)-urea
Show/Hide
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C27H34FN5O
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1
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| 1 |
IC50 = 2.3 nM
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CP0496065
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[1,3,4]thiadiazol-2-yl-urea
Show/Hide
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C22H30FN5OS
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1
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| 1 |
IC50 = 2.3 nM
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CP0350083
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1-[(3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]pentan-3-yl]-3-[3-(2-hydroxypropan-2-yl)-5-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
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C29H40FN7O2
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1
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| 1 |
IC50 = 2.4 nM
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CP0261821
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(S,E)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)prop-1-enyl)-3-(3-acetylphenyl)urea
Show/Hide
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C24H28FN3O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0276231
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropanecarbonyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H38FN5O3S
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1
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| 1 |
IC50 = 2.5 nM
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CP0421874
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1-((2R,3S)-4-(benzyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C31H38FN7O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0486803
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1-((2R,3S)-4-(ethyl((S)-4-(4-fluorophenyl)butan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C25H34FN7O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0553000
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1-((2R,3S)-4-(cyclohexyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C28H38FN7O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0049932
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(S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetylphenyl)urea
Show/Hide
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C24H30FN3O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0461535
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1-(3-Acetyl-phenyl)-3-{(1R,2S)-2-[(R)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C28H36FN3O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0469196
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-phenyl-urea
Show/Hide
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C26H34FN3O
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1
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| 1 |
IC50 = 2.5 nM
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CP0524632
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1-(3-Acetyl-phenyl)-3-(2-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-urea
Show/Hide
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C29H32FN3O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0229224
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(3R,4S)-tert-butyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)pyrrolidine-1-carboxylate
Show/Hide
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C29H40FN5O4S
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1
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| 1 |
IC50 = 2.6 nM
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CP0333900
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(furan-2-ylmethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C30H38FN5O3S
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1
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| 1 |
IC50 = 2.6 nM
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CP0079627
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1-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]-3-[3-(1-methyltetrazol-5-yl)-5-propan-2-ylphenyl]urea
Show/Hide
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C28H38FN7O
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1
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| 1 |
IC50 = 2.6 nM
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CP0091216
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1-[3,5-di(pyrazol-1-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
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C29H34FN7O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0307123
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1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C26H32FN7O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0360146
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1-[3-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]propyl]-3-[3-(1-methyltetrazol-5-yl)-5-propan-2-ylphenyl]urea
Show/Hide
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C27H36FN7O
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1
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| 1 |
IC50 = 2.6 nM
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CP0509666
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1-(3-Acetyl-phenyl)-3-[2-(4-fluoro-benzyl)-piperidin-1-yl]-urea
Show/Hide
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C21H24FN3O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0421888
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropylmethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H40FN5O2S
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1
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| 1 |
IC50 = 2.7 nM
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CP0035825
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1-[3,5-bis(1,3-oxazol-2-yl)phenyl]-3-[(2R,4R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
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C29H32FN5O4
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1
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| 1 |
IC50 = 2.7 nM
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CP0035826
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1-(3,5-diacetylphenyl)-3-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
Show/Hide
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C27H34FN3O3
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1
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| 1 |
IC50 = 2.7 nM
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CP0091219
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1-(3,5-diacetylphenyl)-3-[(2S,4S)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-hydroxybutan-2-yl]urea
Show/Hide
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C27H34FN3O4
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1
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| 1 |
IC50 = 2.7 nM
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CP0495335
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(5-methyl-isoxazol-3-yl)-urea
Show/Hide
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C24H33FN4O2
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1
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| 1 |
IC50 = 2.7 nM
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CP0229220
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-hydroxyethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C27H38FN5O3S
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1
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| 1 |
IC50 = 2.8 nM
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CP0344354
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopentanecarbonyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C31H42FN5O3S
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1
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| 1 |
IC50 = 2.9 nM
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CP0460328
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3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide
Show/Hide
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C28H28FN5O2
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1
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| 1 |
IC50 = 3 nM
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CP0555294
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4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide
Show/Hide
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C29H31FN4O3
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1
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| 1 |
IC50 = 3 nM
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CP0445770
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4S)-1-[2-(4-fluoro-phenyl)-ethyl]-4-trifluoromethyl-piperidin-3-ylmethyl}-urea
Show/Hide
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C26H31F4N7O
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1
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| 1 |
IC50 = 3 nM
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CP0497246
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4S)-1-[2-(4-fluoro-phenyl)-ethyl]-4-phenyl-piperidin-3-ylmethyl}-urea
Show/Hide
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C31H36FN7O
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1
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| 1 |
IC50 = 3 nM
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CP0522505
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1-(3-Acetyl-phenyl)-3-{(1R,2S)-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C28H36FN3O2
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1
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| 1 |
IC50 = 3 nM
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CP0548844
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1-(3-Acetyl-phenyl)-3-[(1R,2S)-2-(4-benzyl-piperidin-1-ylmethyl)-cyclohexyl]-urea
Show/Hide
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C28H37N3O2
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1
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| 1 |
IC50 = 3 nM
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CP0333902
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropanecarbonyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H38FN5O3S
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1
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| 1 |
IC50 = 3.2 nM
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CP0421875
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1-((2R,3S)-4-(cyclohexyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C30H42FN7O2
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1
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| 1 |
IC50 = 3.2 nM
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CP0374504
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1-{(S)-1-[2-(3,4-Difluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C25H31F2N7O
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1
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| 1 |
IC50 = 3.2 nM
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CP0229222
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-propionylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C28H38FN5O3S
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1
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| 1 |
IC50 = 3.3 nM
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CP0454108
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1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C27H38FN7O3
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1
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| 1 |
IC50 = 3.4 nM
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CP0553016
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopentanecarbonyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C31H42FN5O3S
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1
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| 1 |
IC50 = 3.6 nM
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CP0480698
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1-{(S)-1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C25H32ClN7O
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1
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| 1 |
IC50 = 3.6 nM
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CP0522353
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1-((1R,2S)-2-((3-(4-fluorophenyl)propylamino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C25H32FN7O
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1
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| 1 |
IC50 = 3.7 nM
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CP0526007
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-((S)-1-phenethyl-piperidin-3-ylmethyl)-urea
Show/Hide
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C25H33N7O
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1
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| 1 |
IC50 = 3.7 nM
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CP0136069
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1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropylmethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C29H40FN5O2S
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1
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| 1 |
IC50 = 4 nM
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CP0321346
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1-[(2S)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
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C25H32FN7O
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1
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| 1 |
IC50 = 4 nM
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CP0378866
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1-(4-Chloro-benzothiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C27H32ClFN4OS
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1
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| 1 |
IC50 = 4 nM
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CP0453204
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-fluoro-4-methyl-phenyl)-urea
Show/Hide
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C27H35F2N3O
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1
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| 1 |
IC50 = 4 nM
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CP0492856
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1-(3-Acetyl-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C28H36FN3O2
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1
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| 1 |
IC50 = 4 nM
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CP0276162
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1-[(2R)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-4-oxobutan-2-yl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea
Show/Hide
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C25H30FN7O2
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1
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| 1 |
IC50 = 4.2 nM
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CP0391859
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(5-fluoro-2-methyl-phenyl)-urea
Show/Hide
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C27H35F2N3O
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1
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| 1 |
IC50 = 4.6 nM
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CP0344352
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(3S,4S)-methyl 4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate
Show/Hide
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C27H36FN5O4S
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1
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| 1 |
IC50 = 4.9 nM
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CP0547164
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1-{(S)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C23H28FN7O
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1
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| 1 |
IC50 = 5 nM
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CP0382257
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-fluoro-phenyl)-urea
Show/Hide
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C26H33F2N3O
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1
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| 1 |
IC50 = 5 nM
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CP0435560
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(2-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C25H32FN7O
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1
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| 1 |
IC50 = 5.5 nM
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CP0469290
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1-{(S)-1-[2-(2,4-Dichloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C25H31Cl2N7O
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1
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| 1 |
IC50 = 5.5 nM
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CP0378525
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1-((2R,3S)-3-hydroxy-4-(((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C23H31N7O3
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1
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| 1 |
IC50 = 5.7 nM
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CP0263955
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1-(3,5-diacetylphenyl)-3-[(2S)-4-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]butan-2-yl]urea
Show/Hide
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C27H34FN3O3
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1
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| 1 |
IC50 = 5.8 nM
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CP0079965
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(3R,4R)-tert-butyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate
Show/Hide
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C30H42FN5O4S
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1
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| 1 |
IC50 = 6 nM
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CP0421873
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1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-(N-(3-(4-fluorophenyl)propyl)acetamido)-3-hydroxybutan-2-yl)urea
Show/Hide
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C26H34FN7O3
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1
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| 1 |
IC50 = 6 nM
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CP0379279
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1-{(S)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C23H28FN7O
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1
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| 1 |
IC50 = 6 nM
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CP0505683
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1-(4-Bromo-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C26H33BrFN3O
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1
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| 1 |
IC50 = 6 nM
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CP0288318
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-oxopropyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C28H38FN5O3S
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1
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| 1 |
IC50 = 6.9 nM
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CP0540147
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3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester
Show/Hide
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C29H29FN4O3
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1
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| 1 |
IC50 = 7 nM
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CP0136072
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1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)pyrrolidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C24H32FN5O2S
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1
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| 1 |
IC50 = 7.6 nM
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CP0392615
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[4-(4-fluoro-phenyl)-butyl]-piperidin-3-yl}-urea
Show/Hide
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C26H34FN7O
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1
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| 1 |
IC50 = 7.9 nM
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CP0460943
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3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester
Show/Hide
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C30H32FN3O4
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1
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| 1 |
IC50 = 8 nM
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CP0470037
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4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide
Show/Hide
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C30H33FN4O3
|
1
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| 1 |
IC50 = 8 nM
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CP0511611
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4-[3-(3-Cyano-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide
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C28H28FN5O2
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1
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| 1 |
IC50 = 8 nM
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CP0511289
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2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-(3-phenyl-ureido)-benzoic acid methyl ester
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C28H30FN3O3
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1
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| 1 |
IC50 = 9 nM
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CP0454109
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1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(2,2,2-trifluoroethyl)amino)-3-hydroxybutan-2-yl)urea
Show/Hide
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C26H33F4N7O2
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1
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| 1 |
IC50 = 9 nM
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CP0378290
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1-(3-cyanophenyl)-3-[(1R,2S)-2-[[(3R)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
Show/Hide
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C27H33FN4O
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1
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| 1 |
IC50 = 9 nM
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CP0491808
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1-(3-cyanophenyl)-3-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
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C27H33FN4O
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1
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| 1 |
IC50 = 9 nM
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CP0499595
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1-[(1R,2S)-2-(4-Benzyl-piperidin-1-ylmethyl)-cyclohexyl]-3-(3-cyano-phenyl)-urea
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C27H34N4O
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1
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| 1 |
IC50 = 9 nM
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CP0136073
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(3S,4S)-tert-butyl 4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate
Show/Hide
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C30H42FN5O4S
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1
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| 1 |
IC50 = 9.2 nM
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CP0509708
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-[(S)-1-(2-p-tolyl-ethyl)-piperidin-3-ylmethyl]-urea
Show/Hide
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C26H35N7O
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1
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| 1 |
IC50 = 9.7 nM
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CP0194068
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1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea
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C24H30FN3O2
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1
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| 1 |
IC50 = 10 nM
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CP0378086
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1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-fluoro-phenyl)-urea
Show/Hide
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C26H33F2N3O
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1
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| 1 |
IC50 = 10 nM
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CP0424938
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4-Benzyl-1-{6-[3-(3-cyano-phenyl)-ureido]-benzo[1,3]dioxol-5-ylmethyl}-1-methyl-piperidinium; iodide
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C29H31IN4O3
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1
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| 1 |
IC50 = 11 nM
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CP0461453
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1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-3-(3-methoxy-phenyl)-urea
Show/Hide
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C28H32FN3O2
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1
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| 1 |
IC50 = 11 nM
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CP0468055
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2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester
Show/Hide
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C29H32FN3O4
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1
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| 1 |
IC50 = 11 nM
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CP0476957
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1-(3-Cyano-phenyl)-3-(2-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-urea
Show/Hide
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C28H29FN4O2
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1
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| 1 |
IC50 = 11 nM
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CP0490719
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(3-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C25H32FN7O
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1
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| 1 |
IC50 = 12 nM
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CP0494846
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1-(3,4-Difluoro-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C26H32F3N3O
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1
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| 1 |
IC50 = 12 nM
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CP0548845
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1-(3-Cyano-phenyl)-3-{(1R,2S)-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea
Show/Hide
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C27H33FN4O
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1
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| 1 |
IC50 = 12 nM
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CP0554233
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1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-methoxy-phenyl)-urea
Show/Hide
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C27H36FN3O2
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1
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| 1 |
IC50 = 12 nM
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CP0374499
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1-{(R)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C23H28FN7O
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1
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| 1 |
IC50 = 13 nM
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CP0528651
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1-(3-Cyano-phenyl)-3-(2-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-urea
Show/Hide
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C28H29FN4O
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1
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| 1 |
IC50 = 14 nM
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CP0551738
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-yl}-urea
Show/Hide
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C24H30FN7O
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1
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| 1 |
IC50 = 14 nM
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CP0258381
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1-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
Show/Hide
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C27H36FN3O2
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1
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| 1 |
IC50 = 14 nM
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CP0551734
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1-{(1R,2S)-2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-methoxy-phenyl)-urea
Show/Hide
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C27H36FN3O2
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1
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| 1 |
IC50 = 14 nM
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CP0501486
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1-{(R)-1-[3-(4-Fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C24H30FN7O
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1
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| 1 |
IC50 = 15 nM
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CP0501909
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(3S,4S)-tert-butyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)pyrrolidine-1-carboxylate
Show/Hide
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C29H40FN5O4S
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1
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| 1 |
IC50 = 16 nM
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CP0503059
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2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-(3-phenyl-ureido)-benzoic acid
Show/Hide
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C27H28FN3O3
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1
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| 1 |
IC50 = 17 nM
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CP0522352
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1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C25H34FN7O3
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1
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| 1 |
IC50 = 19 nM
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CP0431303
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N-[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]-2-[(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]acetamide
Show/Hide
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C23H25Cl2N3O2S2
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1
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| 1 |
IC50 = 20 nM
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CP0531524
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1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-3-(3-methoxy-phenyl)-urea
Show/Hide
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C28H32FN3O3
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1
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| 1 |
IC50 = 21 nM
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CP0920289
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4-Benzyl-1-{2-[3-(3-cyano-phenyl)-ureido]-5-hydroxy-benzyl}-1-methyl-piperidinium iodide
Show/Hide
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C28H31IN4O2
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1
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| 1 |
IC50 = 21 nM
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CP0522354
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1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-(N-(3-(4-fluorophenyl)propyl)methan-12-ylsulfonamido)-3-hydroxybutan-2-yl)urea
Show/Hide
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C25H34FN7O4S
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1
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| 1 |
IC50 = 21.6 nM
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CP0540908
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1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-3-phenyl-urea
Show/Hide
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C27H30FN3O2
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1
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| 1 |
IC50 = 24 nM
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CP0376168
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1-[(1R,2S)-2-[(3-benzylpiperidin-1-yl)methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
Show/Hide
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C27H37N3O2
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1
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| 1 |
IC50 = 28 nM
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CP0932660
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1-{(S)-1-[4-(4-Fluoro-phenyl)-butyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C25H32FN7O
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1
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| 1 |
IC50 = 29 nM
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CP0442346
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1-[(1R,2S)-2-[[(3R)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
Show/Hide
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C27H36FN3O2
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1
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| 1 |
IC50 = 29 nM
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CP0391860
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1-(3-chlorophenyl)-3-[(1R,2S)-2-[[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
Show/Hide
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C26H33ClFN3O
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1
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| 1 |
IC50 = 31 nM
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CP0085008
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2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide
Show/Hide
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C21H21Cl2N3OS2
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1
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| 1 |
IC50 = 32 nM
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CP0509935
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1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-3-(4-fluoro-phenyl)-urea
Show/Hide
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C27H29F2N3O
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1
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| 1 |
IC50 = 35 nM
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CP0490718
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1-{(S)-1-[3-(4-Fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C24H30FN7O
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1
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| 1 |
IC50 = 36 nM
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CP0460341
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1-(3-Acetyl-phenyl)-3-{6-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzo[1,3]dioxol-5-yl}-urea
Show/Hide
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C29H30FN3O4
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1
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| 1 |
IC50 = 40 nM
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CP0442347
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1-(3-acetylphenyl)-3-[3-[[4-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]urea
Show/Hide
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C28H36FN3O2
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1
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| 1 |
IC50 = 41 nM
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CP0466037
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4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester
Show/Hide
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C30H32FN3O4
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1
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| 1 |
IC50 = 42 nM
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CP0185535
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1-((3S,4R)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)pyrrolidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
Show/Hide
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C24H32FN5O2S
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1
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| 1 |
IC50 = 44 nM
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CP0507575
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1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-hydroxymethyl-phenyl}-3-(3-methoxy-phenyl)-urea
Show/Hide
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C28H32FN3O3
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1
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| 1 |
IC50 = 47 nM
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CP0515799
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2-{[1-(3,4-Dichloro-benzyl)-piperidin-4-ylcarbamoyl]-methylsulfanyl}-benzothiazole-6-carboxylic acid ethyl ester
Show/Hide
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C24H25Cl2N3O3S2
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1
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| 1 |
IC50 = 48 nM
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CP0438432
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1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(3-cyano-phenyl)-urea
Show/Hide
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C28H30N4O2
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1
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| 1 |
IC50 = 49 nM
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CP0460310
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1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-hydroxymethyl-phenyl}-3-phenyl-urea
Show/Hide
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C27H30FN3O2
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1
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| 1 |
IC50 = 53 nM
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CP0374460
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1-[1-(4-Fluoro-benzyl)-piperidin-4-ylmethyl]-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C22H26FN7O
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1
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| 1 |
IC50 = 54 nM
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CP0376470
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1-(3-Cyano-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-4-hydroxymethyl-phenyl}-urea
Show/Hide
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C28H29FN4O2
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1
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| 1 |
IC50 = 55 nM
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CP0421877
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1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(2,2,2-trifluoroethyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C24H29F4N7O2
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1
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| 1 |
IC50 = 59 nM
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CP0515991
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1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(2,2,2-trifluoroethyl)amino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C27H33F4N7O
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1
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| 1 |
IC50 = 60 nM
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CP0424941
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3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester
Show/Hide
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C29H32FN3O4
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1
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| 1 |
IC50 = 64 nM
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CP0540163
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4-[3-(3-Cyano-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester
Show/Hide
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C29H29FN4O3
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1
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| 1 |
IC50 = 67 nM
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CP0487504
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1-[3-[[4-[(4-fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
Show/Hide
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C27H36FN3O2
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1
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| 1 |
IC50 = 78 nM
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CP0376961
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2-(Benzothiazol-2-ylsulfanyl)-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-acetamide
Show/Hide
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C21H22ClN3OS2
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1
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| 1 |
IC50 = 79 nM
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CP0461057
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1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(3-methoxy-phenyl)-urea
Show/Hide
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C28H33N3O3
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1
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| 1 |
IC50 = 81 nM
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CP0485020
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C26H32F3N7O
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1
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| 1 |
IC50 = 82 nM
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CP0555188
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1-(3-Cyano-phenyl)-3-{6-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzo[1,3]dioxol-5-yl}-urea
Show/Hide
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C28H27FN4O3
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1
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| 1 |
IC50 = 85 nM
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CP0515990
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1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C25H34FN7O3
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1
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| 1 |
IC50 = 88 nM
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CP0538926
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1-[2-(4-Benzyl-piperidin-1-ylmethyl)-5-hydroxymethyl-phenyl]-3-(3-cyano-phenyl)-urea
Show/Hide
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C28H30N4O2
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1
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| 1 |
IC50 = 114 nM
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CP0551737
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1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea
Show/Hide
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C26H35N7O2
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1
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| 1 |
IC50 = 120 nM
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CP0376469
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1-(3-Acetyl-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-urea
Show/Hide
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C28H30FN3O2
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1
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| 1 |
IC50 = 125 nM
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CP0389821
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1-{2-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenyl}-3-(3-cyano-phenyl)-urea
Show/Hide
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C28H30N4O
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1
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| 1 |
IC50 = 140 nM
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CP0434584
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1-{6-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-benzo[1,3]dioxol-5-yl}-3-(3-methoxy-phenyl)-urea
Show/Hide
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C28H30FN3O4
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1
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| 1 |
IC50 = 141 nM
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CP0496377
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2-(4-fluorophenyl)-N-[2-[2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethyl]phenyl]acetamide
Show/Hide
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C28H30F2N2O
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1
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| 1 |
IC50 = 153 nM
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CP0493942
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1-{2-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenyl}-3-(3-methoxy-phenyl)-urea
Show/Hide
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C28H33N3O2
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1
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| 1 |
IC50 = 180 nM
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CP0371928
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1-((1R,2S)-3-{adamantan-1-ylmethyl-[3-(4-fluoro-phenyl)-propyl]-amino}-2-hydroxy-1-methyl-propyl)-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C35H48FN7O2
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1
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| 1 |
IC50 = 211 nM
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CP0522230
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1-(3-Acetyl-phenyl)-3-[6-(4-benzyl-piperidin-1-ylmethyl)-benzo[1,3]dioxol-5-yl]-urea
Show/Hide
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C29H31N3O4
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1
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| 1 |
IC50 = 228 nM
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CP0374461
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1-{1-[3-(4-Fluoro-phenyl)-propyl]-piperidin-4-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
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C24H30FN7O
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1
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| 1 |
IC50 = 230 nM
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CP0496373
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1-[6-(4-Benzyl-piperidin-1-ylmethyl)-benzo[1,3]dioxol-5-yl]-3-(3-cyano-phenyl)-urea
Show/Hide
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C28H28N4O3
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1
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| 1 |
IC50 = 237 nM
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CP0560006
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1-((2R,3S)-3-hydroxy-4-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
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C23H31N7O3
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1
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| 1 |
IC50 = 238 nM
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CP0438467
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1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-phenyl-urea
Show/Hide
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C27H31N3O2
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1
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| 1 |
IC50 = 249 nM
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CP0377787
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1-[6-(4-Benzyl-piperidin-1-ylmethyl)-benzo[1,3]dioxol-5-yl]-3-(1H-indazol-6-yl)-urea
Show/Hide
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C28H29N5O3
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1
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| 1 |
IC50 = 260 nM
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CP0401652
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1-[2-(4-Benzyl-piperidin-1-ylmethyl)-4-hydroxy-phenyl]-3-(3-cyano-phenyl)-urea
Show/Hide
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C27H28N4O2
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1
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| 1 |
IC50 = 277 nM
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CP0430863
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2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3-chloro-benzyl)-piperidin-4-yl]-acetamide
Show/Hide
|
C21H22ClN3OS2
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1
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| 1 |
IC50 = 280 nM
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CP0573400
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1-(3-Cyano-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-urea
Show/Hide
|
C27H27FN4O
|
1
|
| 1 |
IC50 = 310 nM
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CP0379278
|
1-{1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-4-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C23H28FN7O
|
1
|
| 1 |
IC50 = 350 nM
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CP0460825
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1-[2-(4-Benzyl-piperidin-1-ylmethyl)-5-hydroxymethyl-phenyl]-3-(3-methoxy-phenyl)-urea
Show/Hide
|
C28H33N3O3
|
1
|
| 1 |
IC50 = 360 nM
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CP0495891
|
1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-3-phenyl-urea
Show/Hide
|
C26H28FN3O
|
1
|
| 1 |
IC50 = 361 nM
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CP0485021
|
1-{(S)-1-[2-(4-Dimethylamino-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C27H38N8O
|
1
|
| 1 |
IC50 = 380 nM
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CP0448903
|
1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(2,5-difluoro-phenyl)-urea
Show/Hide
|
C27H29F2N3O2
|
1
|
| 1 |
IC50 = 410 nM
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CP0510751
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1-((1R,2S)-3-{adamantan-1-ylmethyl-[3-(4-fluoro-phenyl)-propyl]-amino}-2-hydroxy-1-methyl-propyl)-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C33H44FN7O2
|
1
|
| 1 |
IC50 = 421 nM
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CP0380249
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H-indazol-6-yl)-urea
Show/Hide
|
C27H29N5O
|
1
|
| 1 |
IC50 = 450 nM
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CP0448842
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H-indazol-5-yl)-urea
Show/Hide
|
C27H29N5O
|
1
|
| 1 |
IC50 = 450 nM
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CP0449240
|
1-[3-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-cyano-phenyl)-urea
Show/Hide
|
C27H28N4O
|
1
|
| 1 |
IC50 = 450 nM
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CP0507618
|
1-(3-Cyano-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-naphthalen-1-yl}-urea
Show/Hide
|
C31H29FN4O
|
1
|
| 1 |
IC50 = 529 nM
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CP0421872
|
1-((2R,3S)-3-hydroxy-4-(((1R,2R)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
Show/Hide
|
C23H31N7O3
|
1
|
| 1 |
IC50 = 577 nM
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CP0383417
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-methoxy-phenyl)-urea
Show/Hide
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C27H31N3O2
|
1
|
| 1 |
IC50 = 600 nM
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CP0467952
|
1-[3-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H-indazol-5-yl)-urea
Show/Hide
|
C27H29N5O
|
1
|
| 1 |
IC50 = 620 nM
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CP0393456
|
2-(Benzothiazol-2-ylsulfanyl)-N-(1-benzyl-piperidin-4-yl)-acetamide
Show/Hide
|
C21H23N3OS2
|
1
|
| 1 |
IC50 = 750 nM
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CP0376365
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C27H31N3O2
|
1
|
| 1 |
IC50 = 750 nM
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CP0463755
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-cyano-phenyl)-urea
Show/Hide
|
C27H28N4O
|
1
|
| 1 |
IC50 = 750 nM
|
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CP0051245
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-amino-5-(trifluoromethyl)benzamide
Show/Hide
|
C26H34F3N5O3
|
1
|
| 1 |
IC50 = 750 nM
|
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CP0554576
|
4-(4-Benzyl-piperidin-1-ylmethyl)-3-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester
Show/Hide
|
C29H33N3O4
|
1
|
| 1 |
IC50 = 777 nM
|
|
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CP0438500
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-phenyl-urea
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 900 nM
|
|
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CP0463111
|
2-(Benzothiazol-2-ylsulfanyl)-N-(1-cyclohexylmethyl-piperidin-3-ylmethyl)-acetamide
Show/Hide
|
C22H31N3OS2
|
1
|
| 1 |
IC50 = 1000 nM
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CP0499483
|
2-(Benzothiazol-2-ylsulfanyl)-N-(1-benzyl-piperidin-3-ylmethyl)-acetamide
Show/Hide
|
C22H25N3OS2
|
1
|
| 1 |
IC50 = 1000 nM
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CP0389648
|
9-[3-(4-Fluoro-phenyl)-propyl]-4,5,6a,7,8,9,10,10a-octahydro-pyrido[4,3-b]pyrrolo[3,2,1-hi]indole
Show/Hide
|
C22H25FN2
|
1
|
| 1 |
IC50 = 1000 nM
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CP0534382
|
1-[[2-[(4-benzylpiperidin-1-yl)methyl]phenyl]methyl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
IC50 = 1300 nM
|
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CP0160834
|
(S)-N-(2-(3-(4-bromo-2-methylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-amino-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H31BrF3N5O3
|
1
|
| 1 |
IC50 = 1500 nM
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CP0448851
|
1-(1-Benzyl-piperidin-4-yl)-3-{5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-urea
Show/Hide
|
C41H49ClN4O2
|
1
|
| 1 |
IC50 = 1620 nM
|
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CP0424962
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2,5-difluoro-phenyl)-urea
Show/Hide
|
C26H27F2N3O
|
1
|
| 1 |
IC50 = 1750 nM
|
|
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CP0464754
|
1-Benzo[1,3]dioxol-5-ylmethyl-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea
Show/Hide
|
C28H31N3O3
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
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CP0377603
|
1'-(1-phenethylhexahydro-4-pyridinylmethyl)spiro[2,3-dihydro-1H-indene-1,3'-(tetrahydro-1'H-pyrrole)]-2',5'-dione
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0373271
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(2-piperidin-1-yl-ethyl)-urea
Show/Hide
|
C36H47ClN4O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
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CP0403530
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-[2-(4-fluoro-phenyl)-ethyl]-urea
Show/Hide
|
C37H41ClFN3O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
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CP0454737
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(2-dimethylamino-ethyl)-urea
Show/Hide
|
C33H43ClN4O2
|
1
|
| 1 |
IC50 = 2230 nM
|
|
|
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CP0377804
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(3-hydroxy-propyl)-urea
Show/Hide
|
C32H40ClN3O3
|
1
|
| 1 |
IC50 = 2350 nM
|
|
|
|
CP0440734
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-benzyl]-3-(3-methoxy-phenyl)-urea
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
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CP0528916
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-cyclohexylmethyl-urea
Show/Hide
|
C36H46ClN3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0871032
|
CENICRIVIROC MESYLATE
Show/Hide
|
C42H56N4O7S2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
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CP0402897
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-hydroxy-propyl)-urea
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
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CP0395009
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2,2-diphenyl-ethyl)-urea
Show/Hide
|
C34H37N3O
|
1
|
| 1 |
IC50 = 2650 nM
|
|
|
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CP0376491
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-benzyl]-3-(3-cyano-phenyl)-urea
Show/Hide
|
C28H30N4O
|
1
|
| 1 |
IC50 = 2800 nM
|
|
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CP0434605
|
1-tert-Butyl-3-{5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-urea
Show/Hide
|
C33H42ClN3O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0405256
|
1-Benzyl-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea
Show/Hide
|
C27H31N3O
|
1
|
| 1 |
IC50 = 3400 nM
|
|
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CP0438433
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-pyridin-4-yl-urea
Show/Hide
|
C34H37ClN4O2
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
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CP0883286
|
1-[(S)-1-(4-Fluoro-benzyl)-piperidin-3-ylmethyl]-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
Show/Hide
|
C22H26FN7O
|
1
|
| 1 |
IC50 = 3500 nM
|
|
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CP0384170
|
1-(1-Benzyl-piperidin-4-yl)-3-[3-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea
Show/Hide
|
C32H40N4O
|
1
|
| 1 |
IC50 = 3700 nM
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|
|
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CP0218739
|
4-Benzyl-1-(4-phenyl-butyl)-piperidine
Show/Hide
|
C22H29N
|
1
|
| 1 |
IC50 = 3800 nM
|
|
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CP0393942
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-[2-(4-fluoro-phenyl)-ethyl]-urea
Show/Hide
|
C28H32FN3O
|
1
|
| 1 |
IC50 = 3800 nM
|
|
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CP0465469
|
1-(1-Benzyl-piperidin-4-yl)-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea
Show/Hide
|
C32H40N4O
|
1
|
| 1 |
IC50 = 3900 nM
|
|
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CP0503058
|
1-[2-(4-Benzoyl-piperidin-1-ylmethyl)-phenyl]-3-(2,2-diphenyl-ethyl)-urea
Show/Hide
|
C34H35N3O2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
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CP0372694
|
5-(4-Benzyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
Show/Hide
|
C29H32N2
|
1
|
| 1 |
IC50 = 4600 nM
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CP0555191
|
1-[2-(4-Benzoyl-piperidin-1-ylmethyl)-phenyl]-3-(2,5-difluoro-phenyl)-urea
Show/Hide
|
C26H25F2N3O2
|
1
|
| 1 |
IC50 = 4650 nM
|
|
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CP0476971
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(4-trifluoromethyl-phenyl)-urea
Show/Hide
|
C36H37ClF3N3O2
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
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CP0479827
|
4-(3-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-ureido)-piperidine-1-carboxylic acid methyl ester
Show/Hide
|
C36H45ClN4O4
|
1
|
| 1 |
IC50 = 5300 nM
|
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CP0377866
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(2,5-difluoro-phenyl)-urea
Show/Hide
|
C35H36ClF2N3O2
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
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CP0495894
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(4-hydroxy-butyl)-urea
Show/Hide
|
C33H42ClN3O3
|
1
|
| 1 |
IC50 = 5950 nM
|
|
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CP0479823
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-isopropyl-urea
Show/Hide
|
C32H40ClN3O2
|
1
|
| 1 |
IC50 = 6100 nM
|
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CP0268787
|
4-Benzyl-1-phenethyl-piperidine
Show/Hide
|
C20H25N
|
1
|
| 1 |
IC50 = 7100 nM
|
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|
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CP0511595
|
1-Benzo[1,3]dioxol-5-ylmethyl-3-[2-(4-benzoyl-piperidin-1-ylmethyl)-phenyl]-urea
Show/Hide
|
C28H29N3O4
|
1
|
| 1 |
IC50 = 7350 nM
|
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CP0438827
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C36H40ClN3O3
|
1
|
| 1 |
IC50 = 7600 nM
|
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CP0460734
|
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2-piperidin-1-yl-ethyl)-urea
Show/Hide
|
C27H38N4O
|
1
|
| 1 |
IC50 = 7600 nM
|
|
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CP0374727
|
1-Benzyl-3-{5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-urea
Show/Hide
|
C36H40ClN3O2
|
1
|
| 1 |
IC50 = 8300 nM
|
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CP0383392
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-methyl-urea
Show/Hide
|
C30H36ClN3O2
|
1
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| 1 |
IC50 = 8300 nM
|
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CP0545278
|
1,4-Dibenzyl-piperidine
Show/Hide
|
C19H23N
|
1
|
| 1 |
IC50 = 8300 nM
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CP0167321
|
1-Benzyl-4-(4-phenyl-butyl)-piperazine
Show/Hide
|
C21H28N2
|
1
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| 1 |
IC50 = 8400 nM
|
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CP0149004
|
5-(4-(4-chlorophenyl)-4-hydroxy-piperidin-1-yl)-2,2-diphenylpentanenitrile
Show/Hide
|
C28H29ClN2O
|
1
|
| 1 |
IC50 = 9000 nM
|
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CP0460167
|
1-[2-(4-Benzyl-piperazin-1-ylmethyl)-phenyl]-3-[2-(4-fluoro-phenyl)-ethyl]-urea
Show/Hide
|
C27H31FN4O
|
1
|
| 1 |
IC50 = 9200 nM
|
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CP0424944
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-phenyl-urea
Show/Hide
|
C35H38ClN3O2
|
1
|
| 1 |
IC50 = 9800 nM
|
|
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CP0136162
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-3-(ethylamino)-5-(trifluoromethyl)benzamide
Show/Hide
|
C28H38F3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0185497
|
(S)-1-(2-((2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)carbamoyl)-4-(trifluoromethyl)phenyl)-3-isopropylurea
Show/Hide
|
C30H41F3N6O4
|
1
|
| 1 |
IC50 = 10000 nM
|
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CP0199851
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-3-amino-5-(trifluoromethyl)benzamide
Show/Hide
|
C26H34F3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0201872
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H33F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0202246
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-(ethylamino)-5-(trifluoromethyl)benzamide
Show/Hide
|
C28H38F3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0208642
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(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-amino-1-oxopropan-2-ylamino)-2-oxoethyl)-2-amino-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H26F3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0215141
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-amino-1-oxopropan-2-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H25F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0528311
|
(S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-(benzylamino)-5-(trifluoromethyl)benzamide
Show/Hide
|
C33H40F3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389459
|
1-(2,5-Difluoro-phenyl)-3-[2-(4-phenyl-piperidin-1-ylmethyl)-phenyl]-urea
Show/Hide
|
C25H25F2N3O
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
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CP0448837
|
3-Methyl-2-(1-phenethyl-piperidin-4-ylmethyl)-2,3,4,7-tetrahydro-isoindol-1-one
Show/Hide
|
C23H30N2O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0522231
|
1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl)-piperidin-4-ol
Show/Hide
|
C28H33ClN2O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
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CP0374740
|
5-(4-Benzyl-piperazin-1-yl)-2,2-diphenyl-pentanenitrile
Show/Hide
|
C28H31N3
|
1
|
| 1 |
IC50 = 14100 nM
|
|
|
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CP0476709
|
4-(4-Chloro-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol
Show/Hide
|
C21H26ClNO
|
1
|
| 1 |
IC50 = 14500 nM
|
|
|
|
CP0438468
|
1-Benzyl-4-(4-chloro-phenyl)-piperidin-4-ol
Show/Hide
|
C18H20ClNO
|
1
|
| 1 |
IC50 = 18700 nM
|
|
|
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CP0395200
|
1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(3-trifluoromethyl-phenyl)-urea
Show/Hide
|
C36H37ClF3N3O2
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1
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| 1 |
IC50 = 19300 nM
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CP0438858
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1-(1,2-Diphenyl-ethyl)-3-(3-hydroxy-propyl)-urea
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C18H22N2O2
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1
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| 1 |
IC50 = 50000 nM
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