Brief Information of the Compound and Protein
Compound Name
1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-methylpiperidin-4-yl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea
    Show/Hide
PubChem ID
CID: 21362425
Canonical SMILES
CN1CCC(CC1)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1
    Show/Hide
Compound Formula C31H45FN6O2S
Compound Structure
Protein Name
C-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51677
Gene Name
CCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS