Brief Information of the Compound and Protein
Compound Name
1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea
    Show/Hide
PubChem ID
CID: 44447377
Canonical SMILES
CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](C)[C@H](O)Cc1ccc(F)cc1
    Show/Hide
Compound Formula C25H34FN7O3
Compound Structure
Protein Name
C-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51677
Gene Name
CCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 88 nM
   TI
   LI
   LO
   TS