Brief Information of the Compound and Protein
Compound Name
1-{(S)-1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea
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PubChem ID
CID: 44390964
Canonical SMILES
CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(Cl)cc3)C2)cc(c1)-c1nnnn1C
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Compound Formula C25H32ClN7O
Compound Structure
Protein Name
C-C chemokine receptor type 3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51677
Gene Name
CCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.6 nM
   TI
   LI
   LO
   TS