Brief Information of the Compound and Protein
Compound Name
[(1R,3R)-1-[(3S)-3-[(4-fluorophenyl)methyl]piperidin-1-yl]-3-[[3-(1-methyltetrazol-5-yl)phenyl]carbamoylamino]butyl] N-methylcarbamate
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PubChem ID
CID: 44455817
Canonical SMILES
CNC(=O)O[C@H](C[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)N1CCC[C@@H](Cc2ccc(F)cc2)C1
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Compound Formula C27H35FN8O3
Compound Structure
Protein Name
C-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51677
Gene Name
CCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS