3-chloro-4-[4-[4-fluoro-2-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

5-chloro-4-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1H-pyridazin-6-one

3-chloro-4-[4-(2-cyclopropyl-4-fluorophenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

3-chloro-4-[4-[4-fluoro-2-(trifluoromethyl)phenoxy]-2-methyl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

3-chloro-4-[4-(2-chloro-4-fluorophenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

3-chloro-4-[4-[4-chloro-2-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

5-chloro-4-[4-[(2,6-dimethylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

3-chloro-4-[4-[2-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

5-chloro-4-[4-[(1S)-1-(2-methylphenyl)ethyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-bromo-4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[4-[(4-methylcyclohexyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[3-oxo-4-[[2-(trifluoromethoxy)phenyl]methyl]piperazin-1-yl]-1H-pyridazin-6-one

1-benzyl-5-ethyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

1-benzyl-N-(furan-2-ylmethyl)-5-propan-2-ylbenzimidazol-2-amine

3-chloro-4-[4-(2-ethynyl-4-fluorophenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

5-chloro-4-[4-[(2-chlorophenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[4-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

3-chloro-4-[4-(2-chlorophenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

5-chloro-4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

2-[[7-(4-chloro-2,5-dioxopyrrol-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]oxy]-5-fluorobenzonitrile

1-benzyl-N-(furan-2-ylmethyl)-5-methylbenzimidazol-2-amine

3-chloro-4-[4-[2-fluoro-6-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

3-chloro-4-[2-ethyl-4-[4-fluoro-2-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

1-benzyl-5-cyclopropyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

3-chloro-4-[3-[[2-(trifluoromethyl)phenyl]methyl]-6,7-dihydro-4H-imidazo[4,5-c]pyridin-5-yl]pyrrole-2,5-dione

5-ethyl-N-(furan-2-ylmethyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]benzimidazol-2-amine

3-chloro-4-[1-[[2-(trifluoromethyl)phenyl]methyl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]pyrrole-2,5-dione

5-ethyl-1-[(4-fluorophenyl)methyl]-N-(furan-2-ylmethyl)benzimidazol-2-amine

1-benzyl-5-ethyl-N-[2-(furan-2-yl)ethyl]benzimidazol-2-amine

3-chloro-4-[4-(2-ethylphenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

1-benzyl-N-(furan-2-ylmethyl)-5-propylbenzimidazol-2-amine

5-ethyl-N-(furan-2-ylmethyl)-1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-amine

5-cyclopropyl-4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-bromo-4-[4-[(4-fluoro-2-methylphenyl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

1-benzyl-5-ethyl-N-(oxolan-2-ylmethyl)benzimidazol-2-amine

6-oxo-4-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1H-pyridazine-5-carbonitrile

5-bromo-4-[(2R)-2-methyl-4-[(2-methylphenyl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

3-chloro-4-[2-cyclopropyl-4-[4-fluoro-2-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

1-benzyl-N-[(5-chlorofuran-2-yl)methyl]-5-ethylbenzimidazol-2-amine

5-ethyl-N-(furan-2-ylmethyl)-1-[(4-methoxyphenyl)methyl]benzimidazol-2-amine

5-ethyl-N-(furan-2-ylmethyl)-1-[[3-(trifluoromethyl)phenyl]methyl]benzimidazol-2-amine

1-benzyl-5-ethyl-N-(oxolan-3-ylmethyl)benzimidazol-2-amine

5-ethyl-1-[(4-ethylphenyl)methyl]-N-(furan-2-ylmethyl)benzimidazol-2-amine

4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-5-propan-2-yl-1H-pyridazin-6-one

1-benzyl-5-ethyl-N-(thiophen-2-ylmethyl)benzimidazol-2-amine

3-chloro-4-[4-[4-fluoro-2-(2,2,2-trifluoroethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

1-benzyl-5-ethyl-N-(2-morpholin-4-ylethyl)benzimidazol-2-amine

5-bromo-4-[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-1H-pyridazin-6-one

1-benzyl-5-ethyl-N-[(5-methylfuran-2-yl)methyl]benzimidazol-2-amine

1-benzyl-5-ethyl-N-(2-pyridin-4-ylethyl)benzimidazol-2-amine

1-benzyl-5-ethyl-N-(pyridin-2-ylmethyl)benzimidazol-2-amine

1-benzyl-5-ethyl-N-(2-piperidin-1-ylethyl)benzimidazol-2-amine

5-bromo-4-[4-[(2-methylphenyl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

5-ethyl-N-(furan-2-ylmethyl)-1-[(4-methylphenyl)methyl]benzimidazol-2-amine

5-bromo-4-[4-(cyclohexylmethyl)piperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[4-[(1-methylindazol-7-yl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-bromo-4-[4-(1-phenylethyl)piperazin-1-yl]-1H-pyridazin-6-one

4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one

6-(1-benzyl-5-ethylbenzimidazol-2-yl)-2-oxa-6-azaspiro[3.3]heptane

5-ethyl-N-(furan-2-ylmethyl)-1-[[2-(trifluoromethyl)phenyl]methyl]benzimidazol-2-amine

1-benzyl-5-ethyl-2-(4-methylpiperidin-1-yl)benzimidazole

1-benzyl-6-ethyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

3-(1-benzyl-5-ethylbenzimidazol-2-yl)-8-oxa-3-azabicyclo[3.2.1]octane

1-benzyl-2-(furan-2-ylmethylamino)benzimidazol-5-ol

1-benzyl-N-(furan-2-ylmethyl)-6-methylbenzimidazol-2-amine

1-benzyl-5-ethyl-2-(4-methylpiperazin-1-yl)benzimidazole

1-benzyl-5-ethenyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

1-benzyl-5-ethynyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

4-(1-benzyl-5-ethylbenzimidazol-2-yl)morpholine

5-[[(1-benzyl-5-ethylbenzimidazol-2-yl)amino]methyl]furan-2-carbonitrile

8-(1-benzyl-5-ethylbenzimidazol-2-yl)-1-oxa-8-azaspiro[4.5]decane

3-chloro-4-[4-(2-cyclobutyl-4-fluorophenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

4-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1H-pyridazin-6-one

1-(5-chloro-6-oxo-1H-pyridazin-4-yl)-N-methyl-N-[[2-(trifluoromethyl)phenyl]methyl]azetidine-3-carboxamide

3-chloro-4-[4-(2-cyclopentyl-4-fluorophenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

2-[1-(5-chloro-6-oxo-1H-pyridazin-4-yl)azetidin-3-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]acetamide

3-chloro-4-[4-(4-fluoro-2-methylphenoxy)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

1-(5-chloro-6-oxo-1H-pyridazin-4-yl)-N-[[2-(trifluoromethyl)phenyl]methyl]azetidine-3-carboxamide

3-chloro-4-[4-[3-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

4-chloro-2-methyl-5-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]pyridazin-3-one

6-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione

4-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1H-pyrimidin-6-one

3-chloro-4-[4-[4-(trifluoromethyl)phenoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]pyrrole-2,5-dione

5-chloro-4-[4-oxo-3-[[2-(trifluoromethyl)phenyl]methyl]imidazolidin-1-yl]-1H-pyridazin-6-one

1-methyl-6-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]pyrimidine-2,4-dione

1,3-dimethyl-6-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]pyrimidine-2,4-dione

2-[(5-chloro-6-oxo-1H-pyridazin-4-yl)-methylamino]-N-[[2-(trifluoromethyl)phenyl]methyl]acetamide

3-chloro-4-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]pyrrole-2,5-dione

5-ethyl-4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[3-oxo-4-[[2-(trifluoromethyl)pyridin-3-yl]methyl]piperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[4-[(4-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[4-[(3-methylpyridin-2-yl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

4-(4-benzylpiperazin-1-yl)-5-bromo-1H-pyridazin-6-one

5-bromo-4-[4-[(2-methylphenyl)methyl]-1,4-diazepan-1-yl]-1H-pyridazin-6-one

4-bromo-2-methyl-5-[4-[(2-methylphenyl)methyl]piperazin-1-yl]pyridazin-3-one

5-methyl-4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-bromo-4-[3-[(2-methylphenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-1H-pyridazin-6-one

5-methoxy-4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-bromo-4-[3-methyl-4-[(2-methylphenyl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

4-bromo-2-(3-hydroxypropyl)-5-[4-[(2-methylphenyl)methyl]piperazin-1-yl]pyridazin-3-one

5-chloro-4-[4-(oxan-4-ylmethyl)-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

5-bromo-4-[6-[(2-methylphenyl)methyl]-2,6-diazaspiro[3.3]heptan-2-yl]-1H-pyridazin-6-one

4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-5-(oxan-4-yl)-1H-pyridazin-6-one

5-bromo-4-[4-[(1-methylimidazol-2-yl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

5-chloro-4-[4-[(2-methylsulfonylphenyl)methyl]-3-oxopiperazin-1-yl]-1H-pyridazin-6-one

4-[4-[(2-methylphenyl)methyl]-3-oxopiperazin-1-yl]-5-morpholin-4-yl-1H-pyridazin-6-one

4-(4-benzylpiperidin-1-yl)-5-bromo-1H-pyridazin-6-one

5-bromo-4-[(2S)-2-methyl-4-[(2-methylphenyl)methyl]piperazin-1-yl]-1H-pyridazin-6-one

(1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine