| Compound ID |
Compound Name |
Compound Formula |
|
CP0421569
|
N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C28H32Cl2N4O6S2
|
1
|
| 1 |
EC50 = 49 nM
|
|
|
|
CP0384405
|
8-fluoro-3-[4-(4-fluorophenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one
Show/Hide
|
C25H22F2N4O2
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0463671
|
8-fluoro-2-(4-methylpiperazin-1-yl)-3-(4-phenoxyphenyl)quinazolin-4-one
Show/Hide
|
C25H23FN4O2
|
1
|
| 1 |
EC50 = 125 nM
|
|
|
|
CP0455759
|
8-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(trifluoromethylsulfanyl)phenyl]quinazolin-4-one
Show/Hide
|
C20H18F4N4OS
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0384411
|
8-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(trifluoromethoxy)phenyl]quinazolin-4-one
Show/Hide
|
C20H18F4N4O2
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0421567
|
7-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(trifluoromethoxy)phenyl]quinazolin-4-one
Show/Hide
|
C20H18F4N4O2
|
1
|
| 1 |
EC50 = 663 nM
|
|
|
|
CP0485784
|
3-(4-benzylphenyl)-8-fluoro-2-(4-methylpiperazin-1-yl)quinazolin-4-one
Show/Hide
|
C26H25FN4O
|
1
|
| 1 |
EC50 = 670 nM
|
|
|
|
CP0434668
|
N-[(2S)-1-[3-[(2,4-dichlorophenyl)sulfonyl-methylamino]propylamino]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C25H29Cl2N3O4S2
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
|
CP0384406
|
8-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(oxan-4-yloxy)phenyl]quinazolin-4-one
Show/Hide
|
C24H27FN4O3
|
1
|
| 1 |
EC50 = 870 nM
|
|
|
|
CP0485785
|
8-fluoro-2-(4-methylpiperazin-1-yl)-3-(4-propan-2-ylphenyl)quinazolin-4-one
Show/Hide
|
C22H25FN4O
|
1
|
| 1 |
EC50 = 910 nM
|
|
|
|
CP0384412
|
ethyl 4-[8-fluoro-2-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]benzoate
Show/Hide
|
C22H23FN4O3
|
1
|
| 1 |
EC50 = 920 nM
|
|
|
|
CP0463673
|
5-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(trifluoromethoxy)phenyl]quinazolin-4-one
Show/Hide
|
C20H18F4N4O2
|
1
|
| 1 |
EC50 = 1180 nM
|
|
|
|
CP0384407
|
8-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(trifluoromethyl)phenyl]quinazolin-4-one
Show/Hide
|
C20H18F4N4O
|
1
|
| 1 |
EC50 = 1444 nM
|
|
|
|
CP0421568
|
6-fluoro-2-(4-methylpiperazin-1-yl)-3-[4-(trifluoromethoxy)phenyl]quinazolin-4-one
Show/Hide
|
C20H18F4N4O2
|
1
|
| 1 |
EC50 = 2060 nM
|
|
|
|
CP0426587
|
7-fluoro-3-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-one
Show/Hide
|
C20H21FN4O2
|
1
|
| 1 |
EC50 = 4700 nM
|
|
|
|
CP0384413
|
2-[(2R)-2,4-dimethylpiperazin-1-yl]-7-fluoro-3-[4-(trifluoromethyl)phenyl]quinazolin-4-one
Show/Hide
|
C21H20F4N4O
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0549082
|
2-(4-ethylpiperazin-1-yl)-7-fluoro-3-(4-methoxyphenyl)quinazolin-4-one
Show/Hide
|
C21H23FN4O2
|
1
|
| 1 |
EC50 = 12200 nM
|
|
|
|
CP0492478
|
N-[(5-chloro-1,3-thiazol-2-yl)methyl]-1,2-benzothiazol-5-amine
Show/Hide
|
C11H8ClN3S2
|
1
|
| 1 |
EC50 > 15848.93 nM
|
|
|
|
CP0538205
|
N-[(5-chloro-1-methylimidazol-2-yl)methyl]-1,2-benzothiazol-5-amine
Show/Hide
|
C12H11ClN4S
|
1
|
| 1 |
EC50 > 15848.93 nM
|
|
|
|
CP0538206
|
N-[(5-chloro-1,3-thiazol-2-yl)methyl]-1,2-benzothiazol-6-amine
Show/Hide
|
C11H8ClN3S2
|
1
|
| 1 |
EC50 > 15848.93 nM
|
|
|
|
CP0548251
|
5-chloro-N-[(5-chloro-1,3-thiazol-2-yl)methyl]-1,2-benzothiazol-6-amine
Show/Hide
|
C11H7Cl2N3S2
|
1
|
| 1 |
EC50 > 15848.93 nM
|
|
|
|
CP0384409
|
7-fluoro-2-[(3S)-4-methyl-3-propan-2-ylpiperazin-1-yl]-3-[4-(trifluoromethyl)phenyl]quinazolin-4-one
Show/Hide
|
C23H24F4N4O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0477268
|
7-fluoro-3-[4-(trifluoromethyl)phenyl]-2-(3,3,4-trimethylpiperazin-1-yl)quinazolin-4-one
Show/Hide
|
C22H22F4N4O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0488039
|
N-[4-cyclobutyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C25H32Cl2FN5OS
|
1
|
| 1 |
IC50 = 0.85 nM
|
|
|
|
CP0426148
|
N-[4-cyclobutyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]-1-(5-fluoropyridin-2-yl)-5-methylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C24H31Cl2FN6OS
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0434015
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide
Show/Hide
|
C23H27FN6OS
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0465616
|
5,6-dichloro-1-[1-[4-(4-cyanooxan-4-yl)phenyl]piperidin-4-yl]-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C30H36Cl2N6O2
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0402968
|
N-[4-cyclobutyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]-1-(5-fluoropyridin-2-yl)-3-methylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C24H31Cl2FN6OS
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0382989
|
4-[(3S,4R)-1-(2,4-dichlorophenyl)sulfonyl-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl]sulfonylbenzonitrile
Show/Hide
|
C18H16Cl2N2O6S2
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0499701
|
7-ethoxy-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C38H40F6N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0576227
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-1-cyclohexyl-5-methylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C23H36Cl2N6OS
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0577951
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-5-methyl-1-phenylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C23H30Cl2N6OS
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0558451
|
5,6-dichloro-N,N-dimethyl-2-(propan-2-ylamino)-1-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]benzimidazole-4-carboxamide
Show/Hide
|
C27H35Cl2N5O2
|
1
|
| 1 |
IC50 = 12.6 nM
|
|
|
|
CP0535244
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-1-(4,4-difluorocyclohexyl)-5-methylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C23H34Cl2F2N6OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0463709
|
methyl 2-[4-[4-[5,6-dichloro-4-(dimethylcarbamoyl)-2-(propan-2-ylamino)benzimidazol-1-yl]piperidin-1-yl]phenyl]-2-methylpropanoate
Show/Hide
|
C29H37Cl2N5O3
|
1
|
| 1 |
IC50 = 15.8 nM
|
|
|
|
CP0459374
|
1-(4-cyanophenyl)-N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-5-methylpyrazole-4-carboxamide
Show/Hide
|
C24H27N7OS
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0549520
|
4-[(3S,4S)-1-(2,4-dichlorophenyl)sulfonyl-4-hydroxypyrrolidin-3-yl]sulfonylbenzonitrile
Show/Hide
|
C17H14Cl2N2O5S2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0566596
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-1-[(4-fluorophenyl)methyl]-5-methylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C24H31Cl2FN6OS
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0232506
|
5,6-dichloro-1-[1-[4-(2-cyanopropan-2-yl)phenyl]piperidin-4-yl]-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C28H34Cl2N6O
|
1
|
| 1 |
IC50 = 31.6 nM
|
|
|
|
CP0482170
|
5,6-dichloro-1-[1-(4-cyclohexylphenyl)piperidin-4-yl]-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C30H39Cl2N5O
|
1
|
| 1 |
IC50 = 31.6 nM
|
|
|
|
CP0564635
|
4-[(3S,4S)-1-(2,4-dichlorophenyl)sulfonyl-4-hydroxypyrrolidin-3-yl]oxybenzonitrile
Show/Hide
|
C17H14Cl2N2O4S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0113739
|
7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H38BrF3N4O
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0547180
|
3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H36F6N4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0350860
|
2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
Show/Hide
|
C26H28F3N3O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0391694
|
3-[(4-morpholin-4-ylpiperidin-1-yl)methyl]-N-[(1S)-1-phenylethyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C35H37F3N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0436512
|
7-methoxy-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C37H38F6N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0535887
|
N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H39F3N4O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0564636
|
4-[(3S,4S)-1-(2,4-dichlorophenyl)sulfonyl-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl]sulfonylbenzonitrile
Show/Hide
|
C18H16Cl2N2O6S2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0385304
|
1-[1-(4-tert-butylphenyl)piperidin-4-yl]-5,6-dichloro-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C28H37Cl2N5O
|
1
|
| 1 |
IC50 = 50.1 nM
|
|
|
|
CP0402970
|
3,5-dimethoxy-N-[4-phenyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]benzamide;dihydrochloride
Show/Hide
|
C25H31Cl2N3O3S
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0436514
|
6-bromo-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H35BrF6N4O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0465745
|
7-bromo-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H35BrF6N4O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0421038
|
1-tert-butyl-N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-5-methylpyrazole-4-carboxamide;hydrochloride
Show/Hide
|
C21H33ClN6OS
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0076959
|
N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C36H39F3N4O
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0499671
|
7-ethoxy-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C39H43F3N4O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0535245
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-oxazole-5-carboxamide;dihydrochloride
Show/Hide
|
C23H29Cl2N5O2S
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0434016
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-3,5-dimethoxybenzamide
Show/Hide
|
C21H28N4O3S
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0455166
|
3,5-dimethoxy-N-[5-(1-methylpiperidin-4-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C24H27N3O3S
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0482560
|
N-[5-[3-(dimethylamino)propyl]-4-phenyl-1,3-thiazol-2-yl]-3,5-dimethoxybenzamide;dihydrochloride
Show/Hide
|
C23H29Cl2N3O3S
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0434014
|
3,5-dimethoxy-N-[5-(3-morpholin-4-ylpropyl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C25H29N3O4S
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0465746
|
3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1S)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H36F6N4O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0431570
|
3,5-dimethoxy-N-[4-phenyl-5-(3-piperidin-1-ylpropyl)-1,3-thiazol-2-yl]benzamide;dihydrochloride
Show/Hide
|
C26H33Cl2N3O3S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0482171
|
5,6-dichloro-N,N-dimethyl-1-[1-(4-methylphenyl)piperidin-4-yl]-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C25H31Cl2N5O
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0491041
|
5,6-dichloro-N,N-dimethyl-1-[1-(3-methylphenyl)piperidin-4-yl]-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C25H31Cl2N5O
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0391692
|
N-[(1S)-2-methyl-1-phenylpropyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C38H43F3N4O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0473294
|
3,5-dimethoxy-N-[5-(4-methylpiperazin-1-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide;dihydrochloride
Show/Hide
|
C23H28Cl2N4O3S
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0560788
|
4-[(3R,4S)-1-(2,4-dichlorophenyl)sulfonyl-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl]sulfonylbenzonitrile
Show/Hide
|
C18H16Cl2N2O6S2
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0410163
|
N-[(1S)-1-phenylpropyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H41F3N4O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0465618
|
5,6-dichloro-N,N-dimethyl-1-(1-phenylpiperidin-4-yl)-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C24H29Cl2N5O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0436513
|
2-(3-chlorophenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C35H39ClN4O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0402971
|
N-[4-cyclopropyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-3,5-dimethoxybenzamide
Show/Hide
|
C20H26N4O3S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0535239
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-4-phenylthiophene-2-carboxamide
Show/Hide
|
C23H26N4OS2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0441174
|
7-methoxy-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C38H41F3N4O2
|
1
|
| 1 |
IC50 = 250 nM
|
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CP0446877
|
4-(pentafluoro-lambda6-sulfanyl)-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
Show/Hide
|
C20H24F5N3O3S2
|
1
|
| 1 |
IC50 = 260 nM
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CP0577953
|
3,5-dimethoxy-N-[5-(4-methylpiperazin-1-yl)-4-pyridin-3-yl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C22H25N5O3S
|
1
|
| 1 |
IC50 = 290 nM
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CP0402969
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3,5-dimethoxy-N-[4-phenyl-5-(piperidin-1-ylmethyl)-1,3-thiazol-2-yl]benzamide;hydrochloride
Show/Hide
|
C24H28ClN3O3S
|
1
|
| 1 |
IC50 = 310 nM
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CP0391698
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2-(4-chlorophenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C35H39ClN4O
|
1
|
| 1 |
IC50 = 320 nM
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CP0513148
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2-fluoro-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H23F4N3O3S
|
1
|
| 1 |
IC50 = 380 nM
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CP0458444
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4-tert-butyl-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
Show/Hide
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C24H33N3O3S
|
1
|
| 1 |
IC50 = 390 nM
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CP0454760
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N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[4-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C36H39F3N4O
|
1
|
| 1 |
IC50 = 400 nM
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CP0101210
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2-nitro-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H23F3N4O5S
|
2
|
| 1 |
IC50 = 420 nM
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|
| 2 |
IC50 = 570 nM
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CP0441176
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2-(3-methylphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O
|
1
|
| 1 |
IC50 = 500 nM
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|
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CP0465743
|
N-benzyl-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C35H37F3N4O
|
1
|
| 1 |
IC50 = 500 nM
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|
|
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CP0534800
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-2,4-bis(trifluoromethyl)benzamide
Show/Hide
|
C22H23F6N3O3S
|
1
|
| 1 |
IC50 = 540 nM
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|
|
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CP0478419
|
5,6-dichloro-N,N-dimethyl-1-(4-piperidin-1-ylphenyl)-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C24H29Cl2N5O
|
1
|
| 1 |
IC50 = 631 nM
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|
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CP0409612
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H24F3N3O3S
|
1
|
| 1 |
IC50 = 710 nM
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|
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CP0459375
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-1,5-dimethylpyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C18H28Cl2N6OS
|
1
|
| 1 |
IC50 = 730 nM
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|
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CP0409611
|
N-[4-(4-cyclopentylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C23H26F3N3O3S
|
1
|
| 1 |
IC50 = 800 nM
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|
|
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CP0488040
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-5-phenylfuran-2-carboxamide
Show/Hide
|
C23H26N4O2S
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
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CP0575328
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-5-methyl-1-(oxan-4-yl)pyrazole-4-carboxamide;dihydrochloride
Show/Hide
|
C22H34Cl2N6O2S
|
1
|
| 1 |
IC50 = 880 nM
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|
|
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CP0392470
|
N-[4-[4-(diethylamino)piperidin-1-yl]sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C23H28F3N3O3S
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
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CP0404307
|
4-(3-chloropyridin-2-yl)-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
Show/Hide
|
C25H27ClN4O3S
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
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CP0461936
|
2-amino-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H25F3N4O3S
|
1
|
| 1 |
IC50 = 930 nM
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|
|
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CP0482173
|
1-(1-benzylpiperidin-4-yl)-5,6-dichloro-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C25H31Cl2N5O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0391696
|
N-(2-phenylpropan-2-yl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H41F3N4O
|
1
|
| 1 |
IC50 = 1000 nM
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|
|
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CP0486550
|
1-[1-(4-tert-butylbenzoyl)piperidin-4-yl]-5,6-dichloro-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C29H37Cl2N5O2
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
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CP0392471
|
N-[4-[4-[ethyl(methyl)amino]piperidin-1-yl]sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H26F3N3O3S
|
1
|
| 1 |
IC50 = 1280 nM
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|
|
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CP0519869
|
N-[4-[(4-propan-2-yl-1,4-diazepan-1-yl)sulfonyl]phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H26F3N3O3S
|
1
|
| 1 |
IC50 = 1320 nM
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|
|
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CP0509505
|
2-(4-methylphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O
|
1
|
| 1 |
IC50 = 1580 nM
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|
|
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CP0560409
|
4-[(3R,4R)-1-(2,4-dichlorophenyl)sulfonyl-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl]sulfonylbenzonitrile
Show/Hide
|
C18H16Cl2N2O6S2
|
1
|
| 1 |
IC50 = 1585 nM
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|
|
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CP0549519
|
3,5-dimethoxy-N-[5-[3-(4-methylpiperazin-1-yl)propyl]-4-phenyl-1,3-thiazol-2-yl]benzamide;trihydrochloride
Show/Hide
|
C26H35Cl3N4O3S
|
1
|
| 1 |
IC50 = 1700 nM
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|
|
|
CP0552543
|
3,5-dimethoxy-N-[5-(4-methylpiperazin-1-yl)-4-pyridin-2-yl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C22H25N5O3S
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0076960
|
2-phenyl-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C35H40N4O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0391695
|
N-[(1R)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C36H39F3N4O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0410162
|
2-phenyl-N-[(1R)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C35H40N4O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0392472
|
N-[4-[4-(dimethylamino)piperidin-1-yl]sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H24F3N3O3S
|
1
|
| 1 |
IC50 = 2110 nM
|
|
|
|
CP0457708
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H24F3N3O3S
|
1
|
| 1 |
IC50 = 2170 nM
|
|
|
|
CP0315551
|
2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide
Show/Hide
|
C14H22Cl2N2O2S
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0522696
|
5,6-dichloro-N,N-dimethyl-1-[1-(phenylcarbamoyl)piperidin-4-yl]-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C25H30Cl2N6O2
|
1
|
| 1 |
IC50 = 2510 nM
|
|
|
|
CP0410130
|
3-[[4-(dimethylamino)piperidin-1-yl]methyl]-N-[(1S)-1-phenylethyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C33H35F3N4O
|
1
|
| 1 |
IC50 = 2510 nM
|
|
|
|
CP0391693
|
N-[(1S)-1-phenylethyl]-3-[(4-piperazin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C35H38F3N5O
|
1
|
| 1 |
IC50 = 3160 nM
|
|
|
|
CP0540867
|
N-[4-cyclobutyl-5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]-1-methyl-5-phenylpyrazole-3-carboxamide
Show/Hide
|
C23H28N6OS
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0427435
|
5,6-dichloro-1-[1-(4-chlorophenyl)sulfonylpiperidin-4-yl]-N,N-dimethyl-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C24H28Cl3N5O3S
|
1
|
| 1 |
IC50 = 3980 nM
|
|
|
|
CP0399852
|
2-(3-methoxyphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O2
|
1
|
| 1 |
IC50 = 3980 nM
|
|
|
|
CP0404306
|
N-[4-(dimethylsulfamoyl)phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C16H15F3N2O3S
|
1
|
| 1 |
IC50 = 4220 nM
|
|
|
|
CP0450624
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C25H28N4O3S
|
1
|
| 1 |
IC50 = 4930 nM
|
|
|
|
CP0482172
|
5,6-dichloro-N,N-dimethyl-1-[(1-phenylpiperidin-4-yl)methyl]-2-(propan-2-ylamino)benzimidazole-4-carboxamide
Show/Hide
|
C25H31Cl2N5O
|
1
|
| 1 |
IC50 = 5010 nM
|
|
|
|
CP0391697
|
2-(4-methoxyphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O2
|
1
|
| 1 |
IC50 = 5010 nM
|
|
|
|
CP0523314
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
Show/Hide
|
C20H25N3O3S
|
1
|
| 1 |
IC50 = 8530 nM
|
|
|
|
CP0465617
|
2-[4-[4-[5,6-dichloro-4-(dimethylcarbamoyl)-2-(propan-2-ylamino)benzimidazol-1-yl]piperidin-1-yl]phenyl]-2-methylpropanoic acid
Show/Hide
|
C28H35Cl2N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0404308
|
N-[4-(4-propan-2-ylpiperazine-1-carbonyl)phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H24F3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471665
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H24F3N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0534267
|
3,5-dimethoxy-N-[5-(4-methylpiperazin-1-yl)-4-pyridin-4-yl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C22H25N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0465744
|
N-[(1S)-1-phenylethyl]-3-(piperidin-1-ylmethyl)-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C31H30F3N3O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0465747
|
3-[(4-cyclohexylpiperidin-1-yl)methyl]-N-[(1S)-1-phenylethyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H40F3N3O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0420135
|
N-[(1R)-2-amino-2-oxo-1-phenylethyl]-N-[(1R)-1-(3,5-difluorophenyl)ethyl]benzamide
Show/Hide
|
C23H20F2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0375248
|
4-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-[[4-(trifluoromethoxy)phenyl]methyl]sulfamoyl]benzoic acid
Show/Hide
|
C21H13ClF6N2O5S
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
