General Information of the Compound
| Compound ID |
CP0485785
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| Compound Name |
8-fluoro-2-(4-methylpiperazin-1-yl)-3-(4-propan-2-ylphenyl)quinazolin-4-one
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| Structure |
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| Formula |
C22H25FN4O
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| Molecular Weight |
380.467
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| Canonical SMILES |
CC(C)c1ccc(cc1)-n1c(nc2c(F)cccc2c1=O)N1CCN(C)CC1
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| InChI |
InChI=1S/C22H25FN4O/c1-15(2)16-7-9-17(10-8-16)27-21(28)18-5-4-6-19(23)20(18)24-22(27)26-13-11-25(3)12-14-26/h4-10,15H,11-14H2,1-3H3
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| InChIKey |
RYOQWKWQZYVRRB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound