| Compound ID |
Compound Name |
Compound Formula |
|
CP0496300
|
5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C18H20ClF2N5O3S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0532954
|
4-[[2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-4-methoxy-3-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H15F8N3O6
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0553678
|
2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)-5-(trifluoromethyl)pyridine-3-carboxamide
Show/Hide
|
C19H20F5N5O3S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0575405
|
4-[[2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-3-methyl-4-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H15F8N3O5
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0573432
|
6-(cyclopropylmethyl)-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C21H25F2N5O3S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0335842
|
6-(4-ethoxyphenyl)-N-(3-methylphenyl)pyrazine-2-carboxamide
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0535118
|
5-(cyclopropylmethyl)-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C21H25F2N5O3S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0575406
|
4-[[4-chloro-2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-3-methoxybenzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C22H15ClF5N3O6
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0552963
|
4-[[4-chloro-2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-3-methylbenzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C22H15ClF5N3O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0565869
|
2-(4,4-difluoroazepan-1-yl)-5,6-dimethyl-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C19H23F2N5O3S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0532955
|
4-[[2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-3-methoxy-4-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H15F8N3O6
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0552972
|
4-[[3-chloro-2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-4-methoxybenzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C22H15ClF5N3O6
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0471396
|
4-[[2-fluoro-4-methoxy-6-[2-methoxy-4-(trifluoromethoxy)phenoxy]-3-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H16F7N3O6
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0053372
|
N-(3,5-dimethylphenyl)-6-(4-ethoxyphenyl)pyrazine-2-carboxamide
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|
C21H21N3O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0269891
|
6-(4-ethoxyphenyl)-N-[(2-methylphenyl)methyl]pyrazine-2-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0574259
|
(1S)-1-(6-tert-butyl-1H-benzimidazol-2-yl)butan-1-amine
Show/Hide
|
C15H23N3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0535120
|
4-[[2-chloro-6-[2-methoxy-4-(trifluoromethoxy)phenoxy]-3-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C22H14ClF6N3O5
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0535121
|
4-[[2-bromo-6-[2-methoxy-4-(trifluoromethoxy)phenoxy]-3-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C22H14BrF6N3O5
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0552962
|
4-[[3-chloro-2-fluoro-6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C21H13ClF5N3O5
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0535117
|
5-chloro-6-cyclobutyl-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C21H24ClF2N5O3S
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0540099
|
2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)-5-(trifluoromethoxy)pyridine-3-carboxamide
Show/Hide
|
C18H18F5N5O4S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0311517
|
6-(4-chlorophenyl)-N-(3,5-dimethylphenyl)pyrazine-2-carboxamide
Show/Hide
|
C19H16ClN3O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0556979
|
6-cyclopropyl-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C20H23F2N5O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0573433
|
4-[[6-[3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy]-2-methyl-3-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H16F7N3O5
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0575404
|
2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C18H21F2N5O3S
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0564209
|
5-chloro-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C17H18ClF2N5O3S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0542817
|
4-[[6-[2-methoxy-4-(trifluoromethoxy)phenoxy]-2-methyl-3-(trifluoromethyl)benzoyl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H17F6N3O5
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0558741
|
2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)-5-(trifluoromethyl)pyridine-3-carboxamide
Show/Hide
|
C18H18F5N5O3S
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0540098
|
5-chloro-6-cyclopropyl-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C20H22ClF2N5O3S
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0351025
|
N-(3-methylphenyl)-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C19H14F3N3O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0565587
|
2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)-6-(trifluoromethyl)pyridine-3-carboxamide
Show/Hide
|
C18H18F5N5O3S
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0542809
|
6-chloro-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C17H18ClF2N5O3S
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0269892
|
6-(4-chlorophenyl)-N-(3-methylphenyl)pyrazine-2-carboxamide
Show/Hide
|
C18H14ClN3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0335843
|
6-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)pyrazine-2-carboxamide
Show/Hide
|
C19H16ClN3O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0565868
|
5-cyclobutyl-2-(4,4-difluoropiperidin-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C21H25F2N5O3S
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0051021
|
5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
Show/Hide
|
C19H16ClNO4
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0053369
|
6-(4-cyanophenyl)-N-(3,5-dimethylphenyl)pyrazine-2-carboxamide
Show/Hide
|
C20H16N4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0540097
|
5-(2-cyclopropylethynyl)-2-(4,4-difluoropiperidin-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
Show/Hide
|
C22H23F2N5O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0029321
|
PF-6305591
Show/Hide
|
C15H22N4O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0105457
|
N-[(2-methylphenyl)methyl]-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0479081
|
4-[2-[(1R,2R)-1-amino-2-methoxypropyl]-3H-benzimidazol-5-yl]-3-fluorobenzonitrile
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0243027
|
N-[(2-morpholin-4-ylpyridin-3-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C22H20F3N5O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0311516
|
6-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]pyrazine-2-carboxamide
Show/Hide
|
C19H15Cl2N3O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0126707
|
N-(3,5-dimethylphenyl)-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0517642
|
(1R,2R)-1-(6-tert-butyl-1H-benzimidazol-2-yl)-2-methoxypropan-1-amine
Show/Hide
|
C15H23N3O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0344137
|
6-(4-chlorophenyl)-N-[(2-methylphenyl)methyl]pyrazine-2-carboxamide
Show/Hide
|
C19H16ClN3O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0373945
|
[5-(4-tert-butylphenyl)furan-2-yl]-(4-cyclohexylpiperazin-1-yl)methanone
Show/Hide
|
C25H34N2O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0105456
|
6-(4-chlorophenyl)-N-[(2-pyrrolidin-1-ylpyridin-3-yl)methyl]pyrazine-2-carboxamide
Show/Hide
|
C21H20ClN5O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0557297
|
(3R,5R)-5-(6-tert-butyl-1H-benzimidazol-2-yl)pyrrolidin-3-ol
Show/Hide
|
C15H21N3O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0960339
|
(S)-2-(benzyloxy)-1-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)ethan-1-amin
Show/Hide
|
C19H18F3N3O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0088920
|
6-(4-chlorophenyl)-N-[(2-morpholin-4-ylpyridin-3-yl)methyl]pyrazine-2-carboxamide
Show/Hide
|
C21H20ClN5O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0532497
|
(1R,2R)-1-amino-1-(6-propan-2-yl-1H-benzimidazol-2-yl)propan-2-ol
Show/Hide
|
C13H19N3O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0557298
|
6-tert-butyl-2-[(2R)-pyrrolidin-2-yl]-1H-benzimidazole
Show/Hide
|
C15H21N3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0401986
|
(2R,3S)-3-amino-3-(6-tert-butylimidazo[1,2-a]pyridin-2-yl)-2-methylpropanamide
Show/Hide
|
C15H22N4O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0658605
|
3-((5-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)methyl)oxetan-3-amine
Show/Hide
|
C14H14F3N3O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0269893
|
6-(4-cyanophenyl)-N-(3-isopropoxyphenyl)pyrazine-2-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0864600
|
2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H14F3N3O
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0401991
|
(1R,2R)-1-amino-1-(6-tert-butyl-1H-benzimidazol-2-yl)propan-2-ol
Show/Hide
|
C14H21N3O
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0569862
|
(2R)-2-amino-2-(6-tert-butyl-1H-benzimidazol-2-yl)propan-1-ol
Show/Hide
|
C14H21N3O
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0201658
|
5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carboxamide
Show/Hide
|
C19H14N2O2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0894512
|
(S)-1-methoxy-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C14H16F3N3O2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0574258
|
(1R,2R)-1-amino-1-[6-(pentafluoro-lambda6-sulfanyl)-1H-benzimidazol-2-yl]propan-2-ol
Show/Hide
|
C10H12F5N3OS
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0340548
|
N-[(2-chloropyridin-3-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
Show/Hide
|
C18H12ClF3N4O2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0554879
|
(2R)-2-amino-2-(6-tert-butyl-1H-benzimidazol-2-yl)ethanol
Show/Hide
|
C13H19N3O
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0456548
|
US9452986, 62
Show/Hide
|
C21H19F3N4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0553561
|
(3R)-3-amino-3-(6-tert-butyl-1H-benzimidazol-2-yl)propanamide
Show/Hide
|
C14H20N4O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0354725
|
6-(4-cyanophenyl)-N-[(2-methylphenyl)methyl]pyrazine-2-carboxamide
Show/Hide
|
C20H16N4O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0408245
|
N-[6-amino-5-(2,3,5-trichlorophenyl)pyridin-2-yl]acetamide
Show/Hide
|
C13H10Cl3N3O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0345857
|
6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide
Show/Hide
|
C13H10Cl3N3O
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 2600 nM
|
|
|
|
CP0348995
|
N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C17H16ClN5O2
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 700 nM
|
|
|
|
CP0465851
|
US9452986, 512
Show/Hide
|
C21H17F3N4O3
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0401989
|
(1R,2R)-1-amino-1-(6-tert-butyl-1H-benzimidazol-2-yl)-3-methylbutan-2-ol
Show/Hide
|
C16H25N3O
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0211545
|
(R)-N-(1-((3-benzyl-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-1-oxo-3-(2-(trifluoromethyl)phenyl)propan-2-yl)-2-(trifluoromethoxy)benzamide
Show/Hide
|
C32H25F6N5O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0962274
|
2-methyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-1-amine
Show/Hide
|
C14H16F3N3O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0109894
|
N-[6-amino-5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]-3-methyl-1,2-oxazole-4-carboxamide
Show/Hide
|
C17H13F3N4O3
|
2
|
| 1 |
IC50 = 260 nM
|
|
|
| 2 |
IC50 = 530 nM
|
|
|
|
CP0929049
|
(S)-1-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H14F3N3O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0309163
|
(R)-tert-butyl 1-((3-benzyl-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-1-oxo-3-(2-(trifluoromethyl)phenyl)propan-2-ylcarbamate
Show/Hide
|
C29H30F3N5O3
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0218570
|
1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
Show/Hide
|
C15H15ClN2O2
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0309165
|
(R)-tert-butyl 3-(2-chloro-5-fluorophenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate
Show/Hide
|
C30H31ClFN5O3
|
1
|
| 1 |
IC50 = 295 nM
|
|
|
|
CP0401147
|
[5-(4-chlorophenyl)furan-2-yl]-(4-cyclohexylpiperazin-1-yl)methanone
Show/Hide
|
C21H25ClN2O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0538412
|
6-(4-chlorophenyl)-N-[(3-morpholin-4-ylpyridin-4-yl)methyl]pyrazine-2-carboxamide
Show/Hide
|
C21H20ClN5O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0961986
|
(R)-1-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H14F3N3O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0456546
|
US9452986, 47
Show/Hide
|
C24H23F3N4O2
|
1
|
| 1 |
IC50 = 334 nM
|
|
|
|
CP0909521
|
(R)-2-(benzyloxy)-1-(5-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)ethanamine
Show/Hide
|
C19H18F3N3O2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0309167
|
(R)-N-(1-((3-benzyl-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-1-oxo-3-(2-(trifluoromethyl)phenyl)propan-2-yl)-3,3-dimethylbutanamide
Show/Hide
|
C30H32F3N5O2
|
1
|
| 1 |
IC50 = 361 nM
|
|
|
|
CP0309166
|
(R)-N-(1-((3-benzyl-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-1-oxo-3-(2-(trifluoromethyl)phenyl)propan-2-yl)-2-(trifluoromethyl)benzamide
Show/Hide
|
C32H25F6N5O2
|
1
|
| 1 |
IC50 = 366 nM
|
|
|
|
CP0481134
|
US9452986, 431
Show/Hide
|
C20H17F3N4O3
|
1
|
| 1 |
IC50 = 382 nM
|
|
|
|
CP0848853
|
(R)-4-methyl-1-(5-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)pentan-2-amine
Show/Hide
|
C16H20F3N3O
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0155891
|
(R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2,3,6-trifluorophenyl)propan-2-ylcarbamate
Show/Hide
|
C30H30F3N5O3
|
1
|
| 1 |
IC50 = 446 nM
|
|
|
|
CP0202067
|
(R)-N-(1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2,3,6-trifluorophenyl)propan-2-yl)-1-(trifluoromethyl)cyclopropanecarboxamide
Show/Hide
|
C30H25F6N5O2
|
1
|
| 1 |
IC50 = 446 nM
|
|
|
|
CP0456545
|
US9452986, 45
Show/Hide
|
C22H19F3N4O3
|
1
|
| 1 |
IC50 = 468 nM
|
|
|
|
CP0477008
|
US9452986, 64
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 491 nM
|
|
|
|
CP0294421
|
(R)-tert-butyl 3-(2-chlorophenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate
Show/Hide
|
C30H32ClN5O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0515373
|
N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-3-methyl-1,2-oxazole-4-carboxamide
Show/Hide
|
C17H15ClN4O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0512965
|
US9452986, 46
Show/Hide
|
C22H20F2N4O3
|
1
|
| 1 |
IC50 = 501 nM
|
|
|
|
CP0561723
|
(4S)-4-[[(2S)-6-amino-2-[[(2S)-5-carbamimidamido-2-[[(1R,4S,7S,13S,16R,21R,24S,27S,30S,33S,36S,39S,42R,45S,48S,51S,54S,57S,60R,65R,68S,71S,74S)-27,51,74-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-21-[[(2S)-2-[[(2S)-2-aminopent-4-ynoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-68-[(5-bromo-1H-indol-3-yl)methyl]-33-butyl-4,54-bis(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-45-(carboxymethyl)-39-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-30,36-bis(1H-indol-3-ylmethyl)-57-methyl-7,71-bis(2-methylpropyl)-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,67,70,73,76,81-tricosaoxo-18,19,62,63,78,79-hexathia-2,5,8,11,14,23,26,29,32,35,38,41,44,47,50,53,56,59,66,69,72,75,82-tricosazatricyclo[40.34.4.216,60]dooctacontane-65-carbonyl]amino]pentanoyl]amino]hexanoyl]amino]-5-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C162H245BrN48O40S6
|
1
|
| 1 |
IC50 = 509 nM
|
|
|
|
CP0528947
|
(1R,2R)-1-amino-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]propan-2-ol
Show/Hide
|
C11H12F3N3O
|
1
|
| 1 |
IC50 = 534 nM
|
|
|
|
CP0532496
|
4-[2-[(1S,2S)-1-amino-2-hydroxypropyl]-3H-benzimidazol-5-yl]benzonitrile
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
IC50 = 579 nM
|
|
|
|
CP0540710
|
(2R)-2-amino-2-[6-(1-methylcyclopropyl)-1H-benzimidazol-2-yl]ethanol
Show/Hide
|
C13H17N3O
|
1
|
| 1 |
IC50 = 593 nM
|
|
|
|
CP0179132
|
2-(6-tert-butyl-1H-benzimidazol-2-yl)propan-2-amine
Show/Hide
|
C14H21N3
|
1
|
| 1 |
IC50 = 607 nM
|
|
|
|
CP0861344
|
3-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)piperidine
Show/Hide
|
C15H16F3N3O
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0519174
|
US9452986, 2
Show/Hide
|
C20H16F3N3O4S
|
1
|
| 1 |
IC50 = 648 nM
|
|
|
|
CP0547193
|
N-[6-amino-5-(2,3,5-trichlorophenyl)pyridin-2-yl]-3-methyl-1,2-oxazole-4-carboxamide
Show/Hide
|
C16H11Cl3N4O2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0478076
|
US9452986, 344
Show/Hide
|
C18H11F6N3O2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0863975
|
(R)-1-(5-(4-chlorophenyl)-1H-imidazol-2-yl)-4-methylpentan-2-amine
Show/Hide
|
C15H20ClN3
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0155892
|
(R)-tert-butyl 3-(2,6-difluorophenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate
Show/Hide
|
C30H31F2N5O3
|
1
|
| 1 |
IC50 = 685 nM
|
|
|
|
CP0486237
|
US9452986, 49
Show/Hide
|
C21H18F2N4O2
|
1
|
| 1 |
IC50 = 702 nM
|
|
|
|
CP0554857
|
(2R)-2-amino-2-(6-butan-2-yl-1H-benzimidazol-2-yl)ethanol
Show/Hide
|
C13H19N3O
|
1
|
| 1 |
IC50 = 708 nM
|
|
|
|
CP0905252
|
2-(4-(4-chlorophenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C12H14ClN3
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0401988
|
2-[2-[(1R,2R)-1-amino-2-hydroxypropyl]-3H-benzimidazol-5-yl]-2-methylpropanenitrile
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
IC50 = 728 nM
|
|
|
|
CP0456544
|
US9452986, 33
Show/Hide
|
C20H17F3N4O3
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0382606
|
(3S)-3-(6-tert-butyl-1H-benzimidazol-2-yl)-3-(methylamino)propanamide
Show/Hide
|
C15H22N4O
|
1
|
| 1 |
IC50 = 742 nM
|
|
|
|
CP0564612
|
N-[6-amino-5-(2,3,5-trichlorophenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C16H12Cl3N5O
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0561639
|
US9452986, 48
Show/Hide
|
C20H16F3N3O3
|
1
|
| 1 |
IC50 = 774 nM
|
|
|
|
CP0865893
|
(R)-1-fluoro-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H13F4N3O
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0195326
|
(R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethyl)phenyl)propan-2-ylcarbamate
Show/Hide
|
C31H32F3N5O3
|
1
|
| 1 |
IC50 = 793 nM
|
|
|
|
CP0553560
|
(3S)-3-amino-3-(6-tert-butyl-1H-benzimidazol-2-yl)-2,2-dimethylpropanamide
Show/Hide
|
C16H24N4O
|
1
|
| 1 |
IC50 = 797 nM
|
|
|
|
CP0035485
|
(R)-tert-butyl 3-(3-fluoro-2-(trifluoromethyl)phenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate
Show/Hide
|
C31H31F4N5O3
|
1
|
| 1 |
IC50 = 806 nM
|
|
|
|
CP0423890
|
US9452986, 70
Show/Hide
|
C23H20F4N4O2
|
1
|
| 1 |
IC50 = 821 nM
|
|
|
|
CP0155888
|
(R)-N-(1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethyl)phenyl)propan-2-yl)-2-(trifluoromethoxy)benzamide
Show/Hide
|
C34H27F6N5O3
|
1
|
| 1 |
IC50 = 825 nM
|
|
|
|
CP0444979
|
US9452986, 57
Show/Hide
|
C20H18F2N4O3
|
1
|
| 1 |
IC50 = 870 nM
|
|
|
|
CP0336824
|
(R)-tert-butyl 3-(2-fluorophenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate
Show/Hide
|
C30H32FN5O3
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0389200
|
N-[6-amino-5-(2,5-dichlorophenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C16H13Cl2N5O
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0423919
|
US9452986, 44
Show/Hide
|
C22H19F3N4O3
|
1
|
| 1 |
IC50 = 937 nM
|
|
|
|
CP0195328
|
(R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethoxy)phenyl)propan-2-ylcarbamate
Show/Hide
|
C31H32F3N5O4
|
1
|
| 1 |
IC50 = 985 nM
|
|
|
|
CP0519247
|
5-[2-[(1R,2R)-1-amino-2-methoxypropyl]-3H-benzimidazol-5-yl]pyridine-2-carbonitrile
Show/Hide
|
C17H17N5O
|
1
|
| 1 |
IC50 = 998 nM
|
|
|
|
CP0457715
|
(R)-5-(4-chlorophenyl)-N-(1-(4-(3-(4-(cyclopropanecarbonyl)phenoxy)propyl)piperazin-1-yl)-1-oxopropan-2-yl)furan-2-carboxamide
Show/Hide
|
C31H34ClN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0905253
|
2-(4-(4-methoxyphenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H17N3O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0465852
|
US9452986, 521
Show/Hide
|
C21H17F3N4O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0445002
|
US9452986, 580
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 1140 nM
|
|
|
|
CP0555038
|
US9452986, 61
Show/Hide
|
C25H25F3N4O3
|
1
|
| 1 |
IC50 = 1140 nM
|
|
|
|
CP0423841
|
US9452986, 63
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0481234
|
US9452986, 66
Show/Hide
|
C19H15F3N4O2
|
1
|
| 1 |
IC50 = 1180 nM
|
|
|
|
CP0211544
|
(R)-tert-butyl 3-(4-fluoro-2-(trifluoromethyl)phenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate
Show/Hide
|
C31H31F4N5O3
|
1
|
| 1 |
IC50 = 1242 nM
|
|
|
|
CP0512986
|
US9452986, 301
Show/Hide
|
C20H15F4N3O3
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0478094
|
US9452986, 36
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
IC50 = 1420 nM
|
|
|
|
CP0211546
|
N-[(2R)-1-[(3-benzylimidazo[4,5-b]pyridin-2-yl)methylamino]-1-oxo-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C29H30F3N5O2
|
1
|
| 1 |
IC50 = 1458 nM
|
|
|
|
CP0423840
|
US9452986, 56
Show/Hide
|
C19H16F3N3O3
|
1
|
| 1 |
IC50 = 1490 nM
|
|
|
|
CP0486238
|
US9452986, 59
Show/Hide
|
C20H14F5N3O2
|
1
|
| 1 |
IC50 = 1530 nM
|
|
|
|
CP0423913
|
US9452986, 1
Show/Hide
|
C20H17F3N4O2
|
1
|
| 1 |
IC50 = 1550 nM
|
|
|
|
CP0929050
|
(S)-2-amino-3-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propanamide
Show/Hide
|
C13H13F3N4O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0952991
|
(S)-1-(4-(4-chlorophenyl)-1H-imidazol-2-yl)-4-methylpentan-2-amine
Show/Hide
|
C15H20ClN3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0425831
|
US9452986, 621
Show/Hide
|
C21H16F6N4O2
|
1
|
| 1 |
IC50 = 1650 nM
|
|
|
|
CP0456541
|
US9452986, 11
Show/Hide
|
C25H25F3N4O3
|
1
|
| 1 |
IC50 = 1690 nM
|
|
|
|
CP0478075
|
US9452986, 73
Show/Hide
|
C21H17F3N4O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0478074
|
US9452986, 67
Show/Hide
|
C22H22F2N4O2
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0195065
|
(R)-N-(1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethyl)phenyl)propan-2-yl)-1-(trifluoromethyl)cyclopropanecarboxamide
Show/Hide
|
C31H27F6N5O2
|
1
|
| 1 |
IC50 = 1782 nM
|
|
|
|
CP0488606
|
US9452986, 31
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 1860 nM
|
|
|
|
CP0202068
|
(R)-N-(3-(2,6-difluorophenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-yl)-1-(trifluoromethyl)cyclopropanecarboxamide
Show/Hide
|
C30H26F5N5O2
|
1
|
| 1 |
IC50 = 1869 nM
|
|
|
|
CP0544378
|
US9452986, 74
Show/Hide
|
C21H17F3N4O3
|
1
|
| 1 |
IC50 = 1880 nM
|
|
|
|
CP0456549
|
US9452986, 68
Show/Hide
|
C21H20F2N4O2
|
1
|
| 1 |
IC50 = 1890 nM
|
|
|
|
CP0478073
|
US9452986, 55
Show/Hide
|
C22H22F2N4O2
|
1
|
| 1 |
IC50 = 2080 nM
|
|
|
|
CP0893624
|
2-(4-(3-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H14F3N3O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0929051
|
(R)-1-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)-4-methylpentan-2-amine
Show/Hide
|
C14H18ClN3O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0425767
|
US9452986, 622
Show/Hide
|
C19H14F5N3O2
|
1
|
| 1 |
IC50 = 2280 nM
|
|
|
|
CP0481135
|
US9452986, 505
Show/Hide
|
C21H16F3N3O3
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0380551
|
N-[6-amino-5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C17H14F3N5O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0519175
|
US9452986, 10
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
IC50 = 2530 nM
|
|
|
|
CP0532498
|
(1R,2R)-2-methoxy-1-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]propan-1-amine
Show/Hide
|
C12H14F3N3O2
|
1
|
| 1 |
IC50 = 2567 nM
|
|
|
|
CP0964950
|
(R)-4-(2-(2-amino-4-methylpentyl)-1H-imidazol-4-yl)benzonitrile
Show/Hide
|
C16H20N4
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0425766
|
US9452986, 417
Show/Hide
|
C21H17F5N4O2
|
1
|
| 1 |
IC50 = 2750 nM
|
|
|
|
CP0561640
|
US9452986, 58
Show/Hide
|
C20H15F3N4O3
|
1
|
| 1 |
IC50 = 2840 nM
|
|
|
|
CP0456552
|
US9452986, 619
Show/Hide
|
C21H16F5N3O3
|
1
|
| 1 |
IC50 = 2910 nM
|
|
|
|
CP0195066
|
(R)-1-methyl-N-(1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethyl)phenyl)propan-2-yl)cyclopropanecarboxamide
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C31H30F3N5O2
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1
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| 1 |
IC50 = 2975 nM
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CP0442662
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N-[6-amino-5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]benzamide
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C19H14F3N3O2
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1
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| 1 |
IC50 = 3200 nM
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CP0962275
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(S)-2-(1H-imidazol-4-yl)-1-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)ethan-1-amine
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C15H14F3N5O
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1
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| 1 |
IC50 = 3200 nM
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CP0488605
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US9452986, 20
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C21H16F6N4O2
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1
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| 1 |
IC50 = 3230 nM
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CP0929052
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(S)-1-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)-4-methylpentan-2-amine
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C14H18ClN3O
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1
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| 1 |
IC50 = 3400 nM
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CP0456550
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US9452986, 436
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C18H12F5N3O2
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1
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| 1 |
IC50 = 3420 nM
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CP0444977
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US9452986, 22
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C19H16F3N3O3
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1
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| 1 |
IC50 = 3540 nM
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CP0456551
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US9452986, 603
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C21H17F5N4O2
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1
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| 1 |
IC50 = 3670 nM
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CP0535948
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US9452986, 623
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C23H20F3N3O3
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1
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| 1 |
IC50 = 3700 nM
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CP0456543
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US9452986, 25
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C21H17F5N4O2
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1
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| 1 |
IC50 = 3830 nM
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CP0423946
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US9452986, 72
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C21H17F5N4O2
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1
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| 1 |
IC50 = 3840 nM
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CP0110199
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4-[2-(2-amino-3H-benzimidazol-5-yl)-4-chlorophenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C21H13ClF2N6O3S2
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1
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| 1 |
IC50 = 3850 nM
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CP0456547
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US9452986, 52
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C20H15F4N3O2
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1
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| 1 |
IC50 = 3850 nM
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CP0531515
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US9452986, 19
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C20H17F3N4O2
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1
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| 1 |
IC50 = 3960 nM
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CP0415096
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N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpropanamide
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C16H18ClN3O2
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1
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| 1 |
IC50 = 4000 nM
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CP0563172
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US9452986, 51
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C20H15F4N3O2
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1
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| 1 |
IC50 = 4060 nM
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CP0545164
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US9452986, 28
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C22H21F3N4O3
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1
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| 1 |
IC50 = 4220 nM
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CP0493421
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US9452986, 65
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C20H18F3N3O4S
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1
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| 1 |
IC50 = 4230 nM
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CP0561280
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US9452986, 6
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C23H21F3N4O3
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1
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| 1 |
IC50 = 4610 nM
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CP0516716
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N-[6-amino-5-(2-chlorophenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
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C16H14ClN5O
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1
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| 1 |
IC50 = 4900 nM
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CP0456542
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US9452986, 18
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C19H14F3N3O3
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1
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| 1 |
IC50 = 5340 nM
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CP0519401
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N-[6-amino-5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]-3-methyltriazole-4-carboxamide
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C16H13F3N6O2
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1
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| 1 |
IC50 = 7000 nM
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CP0433578
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N-[6-amino-5-(5-chloro-2-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
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C17H16ClN5O2
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1
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| 1 |
IC50 = 7400 nM
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CP0010999
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4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
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C18H12Cl2FN5O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0168191
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4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C19H13ClN6O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0247315
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4-[4-chloro-2-[2-(1-ethylazetidin-3-yl)pyrazol-3-yl]phenoxy]-3-cyano-N-(1,3-thiazol-4-yl)benzenesulfonamide
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C24H21ClN6O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0017968
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3-cyano-4-[2-[2-[(2-piperidin-4-ylethylamino)methyl]pyridin-4-yl]-4-[3-(trifluoromethyl)phenyl]phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C35H32F3N7O3S2
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1
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| 1 |
IC50 >= 10000 nM
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CP0451444
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US9452986, 53
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C23H19F5N4O2
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1
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| 1 |
IC50 = 11000 nM
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CP0515378
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6-amino-5-(2,5-dichlorophenyl)-N-methylpyridine-2-carboxamide
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C13H11Cl2N3O
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1
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| 1 |
IC50 = 12000 nM
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CP0478093
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US9452986, 14
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C20H18F2N4O2
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1
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| 1 |
IC50 = 15100 nM
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CP0478061
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US9452986, 529
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C23H21F3N4O3
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1
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| 1 |
IC50 > 20000 nM
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CP0478072
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US9452986, 620
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C22H22F3N4O2+
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1
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| 1 |
IC50 > 20000 nM
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CP0512959
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US9452986, 23
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C22H18F5N3O2
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1
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| 1 |
IC50 > 20000 nM
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CP0382292
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6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-3-carboxamide
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C13H10Cl3N3O
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1
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| 1 |
IC50 = 24000 nM
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CP0254953
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5-chloro-2-fluoro-4-[2-pyridazin-4-yl-4-(trifluoromethyl)phenoxy]-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Show/Hide
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C19H10ClF4N5O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0539653
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N-[6-amino-5-(2-chloro-4-fluorophenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
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C16H13ClFN5O
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1
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| 1 |
IC50 = 31000 nM
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CP0444626
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6-amino-5-(2-chlorophenyl)-N-methylpyridine-2-carboxamide
Show/Hide
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C13H12ClN3O
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1
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| 1 |
IC50 > 32000 nM
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CP0444627
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6-amino-5-(4-chlorophenyl)-N-methylpyridine-2-carboxamide
Show/Hide
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C13H12ClN3O
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1
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| 1 |
IC50 > 32000 nM
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CP0484352
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6-amino-5-(3,5-dichlorophenyl)-N-methylpyridine-2-carboxamide
Show/Hide
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C13H11Cl2N3O
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1
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| 1 |
IC50 > 32000 nM
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CP0547191
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6-amino-5-(3-chlorophenyl)-N-methylpyridine-2-carboxamide
Show/Hide
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C13H12ClN3O
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1
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| 1 |
IC50 > 32000 nM
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CP0076327
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1-(2,6-dimethylphenoxy)-2-propanolamine
Show/Hide
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C11H17NO
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1
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| 1 |
IC50 = 56000 nM
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CP0002226
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6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine
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C9H7Cl2N5
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2
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| 1 |
IC50 = 96000 nM
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| 2 |
IC50 = 98000 nM
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CP0865892
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2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-ol
Show/Hide
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C13H13F3N2O2
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1
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| 1 |
IC50 > 1000 nM
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CP0909522
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1-(2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-yl)urea
Show/Hide
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C14H15F3N4O2
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1
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| 1 |
IC50 > 1000 nM
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CP0909523
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2-(4-phenyl-1H-imidazol-2-yl)propan-2-amine
Show/Hide
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C12H15N3
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1
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| 1 |
IC50 > 1000 nM
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CP0929053
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2-(tert-butyl)-4-(4-(trifluoromethoxy)phenyl)-1H-imidazole
Show/Hide
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C14H15F3N2O
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1
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| 1 |
IC50 > 1000 nM
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CP0944263
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1,3-difluoro-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
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C13H12F5N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0954783
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N-(2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-yl)acetamide
Show/Hide
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C15H16F3N3O2
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1
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| 1 |
IC50 > 1000 nM
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CP0960340
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2-(5-(4-(methylsulfonyl)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
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C13H17N3O2S
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1
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| 1 |
IC50 > 1000 nM
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CP0396347
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(4S)-4-[[(2S)-6-amino-2-[[(2S)-5-carbamimidamido-2-[[(1R,4S,7S,13S,16R,21R,24S,27S,30S,33S,36S,39S,42R,45S,48S,51S,54S,57S,60R,65R,68S,71S,74S)-27,51,74-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-21-[[(2S)-2-[[(2S)-2-aminopent-4-ynoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-33-butyl-4,54-bis(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-45-(carboxymethyl)-39-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-30,36,68-tris(1H-indol-3-ylmethyl)-57-methyl-7,71-bis(2-methylpropyl)-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,67,70,73,76,81-tricosaoxo-18,19,62,63,78,79-hexathia-2,5,8,11,14,23,26,29,32,35,38,41,44,47,50,53,56,59,66,69,72,75,82-tricosazatricyclo[40.34.4.216,60]dooctacontane-65-carbonyl]amino]pentanoyl]amino]hexanoyl]amino]-5-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
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C162H246N48O40S6
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1
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| 1 |
IC50 > 1000 nM
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CP0445933
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(4S)-4-amino-5-[[(2S)-1-[[(1R,4S,7S,13S,16R,21R,24S,27S,30S,33S,36S,39S,42R,45S,48S,51S,54S,57S,60R,65R,68S,71S,74S)-65-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-27,74-bis(4-aminobutyl)-24-(3-amino-3-oxopropyl)-68-[(5-bromo-1H-indol-3-yl)methyl]-33-butyl-4,54-bis(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-45-(carboxymethyl)-39-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-30,36-bis(1H-indol-3-ylmethyl)-51,57-dimethyl-7,71-bis(2-methylpropyl)-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,67,70,73,76,81-tricosaoxo-18,19,62,63,78,79-hexathia-2,5,8,11,14,23,26,29,32,35,38,41,44,47,50,53,56,59,66,69,72,75,82-tricosazatricyclo[40.34.4.216,60]dooctacontan-21-yl]amino]-1-oxopent-4-yn-2-yl]amino]-5-oxopentanoic acid
Show/Hide
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C155H236BrN47O41S6
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1
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| 1 |
IC50 > 1000 nM
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CP0517643
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1-(6-tert-butyl-1H-benzimidazol-2-yl)butan-1-ol
Show/Hide
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C15H22N2O
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1
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| 1 |
IC50 > 1000 nM
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CP0532494
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(2S)-2-amino-2-(6-tert-butylquinoxalin-2-yl)ethanol;hydrochloride
Show/Hide
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C14H20ClN3O
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1
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| 1 |
IC50 > 1000 nM
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CP0532495
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(2R)-2-amino-2-(6-tert-butylquinoxalin-2-yl)ethanol;hydrochloride
Show/Hide
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C14H20ClN3O
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1
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| 1 |
IC50 > 1000 nM
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CP0553538
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(2S)-2-amino-2-(7-tert-butylquinoxalin-2-yl)ethanol;hydrochloride
Show/Hide
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C14H20ClN3O
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1
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| 1 |
IC50 > 1000 nM
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CP0569861
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(2R)-2-amino-2-(7-tert-butylquinoxalin-2-yl)ethanol
Show/Hide
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C14H19N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0319111
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4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C18H13ClFN5O3S2
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1
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| 1 |
IC50 > 3000 nM
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