Brief Information of the Compound and Protein
Compound Name
5-cyclobutyl-2-(4,4-difluoropiperidin-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)pyridine-3-carboxamide
    Show/Hide
PubChem ID
CID: 146525815
Canonical SMILES
Cc1nc(N2CCC(F)(F)CC2)c(cc1C1CCC1)C(=O)Nc1ccnc(c1)S(N)(=O)=O
    Show/Hide
Compound Formula C21H25F2N5O3S
Compound Structure
Protein Name
Sodium channel protein type 10 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated sodium channel
Uniprot ID
Q9Y5Y9
Gene Name
SCN10A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 6.5 nM
   TI
   LI
   LO
   TS