Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-N-(1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethyl)phenyl)propan-2-yl)-1-(trifluoromethyl)cyclopropanecarboxamide
    Show/Hide
 PubChem ID
CID: 44447277
Canonical SMILES
FC(F)(F)c1ccccc1C[C@@H](NC(=O)C1(CC1)C(F)(F)F)C(=O)NCc1nc2cccnc2n1C1(CC1)c1ccccc1
    Show/Hide
Compound Formula C31H27F6N5O2
Compound Structure
Protein Name
 Protein Info 
Sodium channel protein type 10 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated sodium channel
Uniprot ID
Q9Y5Y9
Gene Name
SCN10A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1782 nM
   TI
   LI
   LO
   TS