| Compound ID |
Compound Name |
Compound Formula |
|
CP0954078
|
8-hydroxy-5-(1-hydroxy-2-(4-(4-hydroxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H25ClN2O4
|
1
|
| 1 |
EC50 = 0.01072 nM
|
|
|
|
CP0958106
|
5-(2-(4-(4-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H26Cl2N2O3
|
1
|
| 1 |
EC50 = 0.01259 nM
|
|
|
|
CP0944327
|
8-hydroxy-5-(1-hydroxy-2-(4-m-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O3
|
1
|
| 1 |
EC50 = 0.01288 nM
|
|
|
|
CP0943065
|
8-hydroxy-5-(1-hydroxy-2-(4-(3-hydroxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H25ClN2O4
|
1
|
| 1 |
EC50 = 0.01349 nM
|
|
|
|
CP0887725
|
8-hydroxy-5-(1-hydroxy-2-(4-(2-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 = 0.01479 nM
|
|
|
|
CP0423780
|
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(3-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C21H27ClN2O5
|
1
|
| 1 |
EC50 = 0.01622 nM
|
|
|
|
CP0964080
|
8-hydroxy-5-(1-hydroxy-2-(2-methyl-4-p-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O3
|
1
|
| 1 |
EC50 = 0.0166 nM
|
|
|
|
CP0868555
|
8-hydroxy-5-(1-hydroxy-2-(4-o-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O3
|
1
|
| 1 |
EC50 = 0.01738 nM
|
|
|
|
CP0951005
|
8-hydroxy-5-(1-hydroxy-2-(2-methyl-4-o-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O3
|
1
|
| 1 |
EC50 = 0.01778 nM
|
|
|
|
CP0966209
|
(R)-5-(2-(4-(4-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H26Cl2N2O3
|
1
|
| 1 |
EC50 = 0.01778 nM
|
|
|
|
CP0887723
|
8-hydroxy-5-(1-hydroxy-2-(4-(3-hydroxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 = 0.0182 nM
|
|
|
|
CP0954079
|
5-(2-(4-(2-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H26Cl2N2O3
|
1
|
| 1 |
EC50 = 0.0182 nM
|
|
|
|
CP0965873
|
8-hydroxy-5-(1-hydroxy-2-(4-(4-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 = 0.0182 nM
|
|
|
|
CP0958798
|
8-hydroxy-5-(1-hydroxy-2-(2-methyl-4-m-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O3
|
1
|
| 1 |
EC50 = 0.0195 nM
|
|
|
|
CP0887724
|
5-(2-(3-(3,5-difluorophenyl)propylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C20H21ClF2N2O3
|
1
|
| 1 |
EC50 = 0.02138 nM
|
|
|
|
CP0958765
|
8-hydroxy-5-(1-hydroxy-2-(4-(3-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 = 0.02138 nM
|
|
|
|
CP0958764
|
8-hydroxy-5-(1-hydroxy-2-(4-(2-methoxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O4
|
1
|
| 1 |
EC50 = 0.02239 nM
|
|
|
|
CP0958800
|
(R)-5-(2-(4-(3-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H26Cl2N2O3
|
1
|
| 1 |
EC50 = 0.02239 nM
|
|
|
|
CP0887726
|
5-(2-(4-(3-fluorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H24ClFN2O3
|
1
|
| 1 |
EC50 = 0.02344 nM
|
|
|
|
CP0542110
|
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(2-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C22H29ClN2O5
|
1
|
| 1 |
EC50 = 0.02399 nM
|
|
|
|
CP0868554
|
5-(2-(3-(3-fluorophenyl)propylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C20H22ClFN2O3
|
1
|
| 1 |
EC50 = 0.02455 nM
|
|
|
|
CP0468963
|
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(4-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C21H27ClN2O5
|
1
|
| 1 |
EC50 = 0.0257 nM
|
|
|
|
CP0868557
|
8-hydroxy-5-(1-hydroxy-2-(4-(3-methoxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O4
|
1
|
| 1 |
EC50 = 0.0263 nM
|
|
|
|
CP0423781
|
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(3-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C22H29ClN2O5
|
1
|
| 1 |
EC50 = 0.02754 nM
|
|
|
|
CP0956215
|
5-(2-(4-(4-fluorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H24ClFN2O3
|
1
|
| 1 |
EC50 = 0.02818 nM
|
|
|
|
CP0957369
|
8-hydroxy-5-(1-hydroxy-2-(3-(3-(trifluoromethyl)phenyl)propylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H22ClF3N2O3
|
1
|
| 1 |
EC50 = 0.02818 nM
|
|
|
|
CP0526865
|
6-hydroxy-8-[1-hydroxy-2-[[4-(2-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C22H29ClN2O5
|
1
|
| 1 |
EC50 = 0.02884 nM
|
|
|
|
CP0887728
|
8-hydroxy-5-((R)-1-hydroxy-2-((R)-4-(2-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 = 0.02884 nM
|
|
|
|
CP0526867
|
6-hydroxy-8-[1-hydroxy-2-[[4-(3-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C21H27ClN2O5
|
1
|
| 1 |
EC50 = 0.0309 nM
|
|
|
|
CP0943067
|
8-hydroxy-5-(1-hydroxy-2-(4-(4-methoxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O4
|
1
|
| 1 |
EC50 = 0.0309 nM
|
|
|
|
CP0468962
|
6-hydroxy-8-[1-hydroxy-2-[(2-methyl-4-phenylbutan-2-yl)amino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 0.03236 nM
|
|
|
|
CP0960790
|
5-(2-(4-(4-chlorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H24Cl2N2O3
|
1
|
| 1 |
EC50 = 0.03311 nM
|
|
|
|
CP0962608
|
5-(2-(4-(2-chlorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H24Cl2N2O3
|
1
|
| 1 |
EC50 = 0.03388 nM
|
|
|
|
CP0473096
|
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(4-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C22H29ClN2O5
|
1
|
| 1 |
EC50 = 0.03548 nM
|
|
|
|
CP0930983
|
8-hydroxy-5-(1-hydroxy-2-(4-(4-hydroxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 = 0.03631 nM
|
|
|
|
CP0868573
|
8-hydroxy-5-(1-hydroxy-2-(3-m-tolylpropylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
EC50 = 0.03802 nM
|
|
|
|
CP0951004
|
8-hydroxy-5-(1-hydroxy-2-(4-p-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C22H27ClN2O3
|
1
|
| 1 |
EC50 = 0.03802 nM
|
|
|
|
CP0530797
|
6-hydroxy-8-[1-hydroxy-2-[[4-(4-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C21H27ClN2O5
|
1
|
| 1 |
EC50 = 0.03981 nM
|
|
|
|
CP0479011
|
8-hydroxy-5-[1-hydroxy-2-[3-(3-methoxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H24N2O4
|
1
|
| 1 |
EC50 = 0.04074 nM
|
|
|
|
CP0482749
|
8-hydroxy-5-[1-hydroxy-2-[(2-methyl-4-phenylbutan-2-yl)amino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
EC50 = 0.04074 nM
|
|
|
|
CP0455840
|
8-hydroxy-5-[1-hydroxy-2-[3-(2-methoxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H24N2O4
|
1
|
| 1 |
EC50 = 0.04266 nM
|
|
|
|
CP0065062
|
1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol
Show/Hide
|
C25H37NO4
|
5
|
| 1 |
EC50 = 0.04467 nM
|
|
|
| 2 |
EC50 = 0.07762 nM
|
|
|
| 3 |
EC50 = 0.1349 nM
|
|
|
| 4 |
EC50 = 0.33 nM
|
|
|
| 5 |
Ki = 2.4 nM
|
|
|
|
CP0943066
|
8-hydroxy-5-(1-hydroxy-2-(4-(3,4,5-trimethoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C24H31ClN2O6
|
1
|
| 1 |
EC50 = 0.04467 nM
|
|
|
|
CP0967149
|
5-(2-(3-(4-fluorophenyl)propylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C20H22ClFN2O3
|
1
|
| 1 |
EC50 = 0.04677 nM
|
|
|
|
CP0435689
|
8-hydroxy-5-[1-hydroxy-2-[3-(2-hydroxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
EC50 = 0.04898 nM
|
|
|
|
CP0468960
|
6-hydroxy-8-[1-hydroxy-2-[[4-(4-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C22H29ClN2O5
|
1
|
| 1 |
EC50 = 0.04898 nM
|
|
|
|
CP0525486
|
6-hydroxy-8-[1-hydroxy-2-[[4-(3-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C22H29ClN2O5
|
1
|
| 1 |
EC50 = 0.04898 nM
|
|
|
|
CP0534393
|
8-hydroxy-5-[1-hydroxy-2-[3-(4-hydroxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
EC50 = 0.05012 nM
|
|
|
|
CP0435688
|
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-3,5,5-trimethylhexanamide
Show/Hide
|
C29H39N3O4
|
1
|
| 1 |
EC50 = 0.05129 nM
|
|
|
|
CP0652587
|
SID50085961
Show/Hide
|
C11H18ClNO3
|
1
|
| 1 |
EC50 = 0.05495 nM
|
|
|
|
CP0959115
|
8-hydroxy-5-(1-hydroxy-2-(3-o-tolylpropylamino)ethyl)quinolin-2(1H)-one Hydrochloride
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
EC50 = 0.05754 nM
|
|
|
|
CP0479007
|
8-hydroxy-5-[(1R)-1-hydroxy-2-[(2-methyl-4,4-diphenylbutan-2-yl)amino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C28H30N2O3
|
1
|
| 1 |
EC50 = 0.06457 nM
|
|
|
|
CP0956216
|
5-(2-(4-(3-chlorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H24Cl2N2O3
|
1
|
| 1 |
EC50 = 0.07244 nM
|
|
|
|
CP0539325
|
8-hydroxy-5-[1-hydroxy-2-(3-phenylpropylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
EC50 = 0.07413 nM
|
|
|
|
CP0558032
|
8-hydroxy-5-[1-hydroxy-2-[3-(4-methoxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H24N2O4
|
1
|
| 1 |
EC50 = 0.07413 nM
|
|
|
|
CP0567326
|
5-[2-[[4,4-bis(4-fluorophenyl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C28H28F2N2O3
|
1
|
| 1 |
EC50 = 0.07586 nM
|
|
|
|
CP0455839
|
5-[(1R)-2-[[4,4-bis(4-fluorophenyl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C28H28F2N2O3
|
1
|
| 1 |
EC50 = 0.08128 nM
|
|
|
|
CP0958102
|
8-hydroxy-5-(1-hydroxy-2-(3-(3,4,5-trimethoxyphenyl)propylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C23H29ClN2O6
|
1
|
| 1 |
EC50 = 0.08318 nM
|
|
|
|
CP0451157
|
BI 1744
Show/Hide
|
C21H26N2O5
|
1
|
| 1 |
EC50 = 0.0871 nM
|
|
|
|
CP0887727
|
8-hydroxy-5-(1-hydroxy-2-(3-p-tolylpropylamino)ethyl)quinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
EC50 = 0.0955 nM
|
|
|
|
CP0398266
|
[1-[3-[3-[2-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]anilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O6
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0065922
|
4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
Show/Hide
|
C13H21NO3
|
1
|
| 1 |
EC50 = 0.11 nM
|
|
|
|
CP0445804
|
[1-[3-[5-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]pentylamino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C37H45N5O6
|
1
|
| 1 |
EC50 = 0.1259 nM
|
|
|
|
CP0468959
|
8-[2-[3-(3,5-difluorophenyl)propylamino]-1-hydroxyethyl]-6-hydroxy-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H21ClF2N2O4
|
1
|
| 1 |
EC50 = 0.1288 nM
|
|
|
|
CP0534398
|
8-hydroxy-5-[1-hydroxy-2-[3-(4-phenylphenyl)propylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C26H26N2O3
|
1
|
| 1 |
EC50 = 0.1318 nM
|
|
|
|
CP0468961
|
6-hydroxy-8-[(1R)-1-hydroxy-2-[(2-methyl-4,4-diphenylbutan-2-yl)amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C27H31ClN2O4
|
1
|
| 1 |
EC50 = 0.1413 nM
|
|
|
|
CP0455838
|
8-hydroxy-5-[1-hydroxy-2-(4-phenylbutylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
EC50 = 0.1514 nM
|
|
|
|
CP0379313
|
[1-[2-[[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-2,5-dimethylbenzoyl]amino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O6
|
1
|
| 1 |
EC50 = 0.1585 nM
|
|
|
|
CP0413266
|
[1-[3-[[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]cyclohexyl]amino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C39H47N5O6
|
1
|
| 1 |
EC50 = 0.1585 nM
|
|
|
|
CP0537196
|
8-hydroxy-5-[1-hydroxy-2-(2-phenoxyethylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O4
|
1
|
| 1 |
EC50 = 0.1622 nM
|
|
|
|
CP0530795
|
6-hydroxy-8-[1-hydroxy-2-[3-(3-hydroxyphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H23ClN2O5
|
1
|
| 1 |
EC50 = 0.1738 nM
|
|
|
|
CP0531759
|
8-[(1R)-2-[[4,4-bis(4-fluorophenyl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]-6-hydroxy-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C27H29ClF2N2O4
|
1
|
| 1 |
EC50 = 0.1738 nM
|
|
|
|
CP0066323
|
CAS_73573-87-2
Show/Hide
|
C19H24N2O4
|
2
|
| 1 |
EC50 = 0.19 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0442108
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-2-methylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O6
|
1
|
| 1 |
EC50 = 0.1995 nM
|
|
|
|
CP0550007
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-3-methylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O6
|
1
|
| 1 |
EC50 = 0.1995 nM
|
|
|
|
CP0068209
|
4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride
Show/Hide
|
C11H17NO3
|
8
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
EC50 = 0.2138 nM
|
|
|
| 3 |
EC50 = 0.3162 nM
|
|
|
| 4 |
EC50 = 5.954 nM
|
|
|
| 5 |
EC50 = 87 nM
|
|
|
| 6 |
EC50 = 120 nM
|
|
|
| 7 |
Ki = 2.44 nM
|
|
|
| 8 |
Ki = 192 nM
|
|
|
|
CP0468956
|
6-hydroxy-8-[1-hydroxy-2-[3-(2-hydroxyphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H23ClN2O5
|
1
|
| 1 |
EC50 = 0.2138 nM
|
|
|
|
CP0482750
|
8-hydroxy-5-[1-hydroxy-2-[(2-methyl-4,4-diphenylbutan-2-yl)amino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C28H30N2O3
|
1
|
| 1 |
EC50 = 0.2188 nM
|
|
|
|
CP0537197
|
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-4-methylpentanamide
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
EC50 = 0.2239 nM
|
|
|
|
CP0088670
|
Batefenterol
Show/Hide
|
C40H42ClN5O7
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0384251
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-3-methoxy-2-methylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O7
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0384252
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-3-methoxyanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O7
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0398520
|
[1-[3-[2-chloro-4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]anilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C39H40ClN5O6
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0413169
|
[1-[2-[[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O6
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0550009
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]anilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C39H41N5O6
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0542089
|
6-hydroxy-8-[1-hydroxy-2-(4-phenylbutylamino)ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H25ClN2O4
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0387977
|
(R,R)-(-)-fenoterol
Show/Hide
|
C17H21NO4
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
Kd = 347 nM
|
|
|
|
CP0436392
|
(R,R)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylamino-propane
Show/Hide
|
C18H23NO4
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
Kd = 479 nM
|
|
|
|
CP0557256
|
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]benzamide
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
EC50 = 0.302 nM
|
|
|
|
CP0441217
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-5-methoxy-2-methylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O7
|
1
|
| 1 |
EC50 = 0.3162 nM
|
|
|
|
CP0468954
|
6-hydroxy-8-[1-hydroxy-2-(3-phenylpropylamino)ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H23ClN2O4
|
1
|
| 1 |
EC50 = 0.3162 nM
|
|
|
|
CP0381761
|
(R)-1-(8-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)octyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C37H46N4O5
|
2
|
| 1 |
EC50 = 0.32 nM
|
|
|
| 2 |
Ki = 3.4 nM
|
|
|
|
CP0116358
|
(R)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)nonyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C38H48N4O5
|
3
|
| 1 |
EC50 = 0.36 nM
|
|
|
| 2 |
EC50 = 0.3981 nM
|
|
|
| 3 |
Ki = 3.5 nM
|
|
|
|
CP0468957
|
6-hydroxy-8-[1-hydroxy-2-[3-(2-methoxyphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H25ClN2O5
|
1
|
| 1 |
EC50 = 0.3802 nM
|
|
|
|
CP0550008
|
[1-[3-[2-chloro-4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-3-methoxyanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H42ClN5O7
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0389036
|
5-[(1R)-1-hydroxy-2-[[(2R)-1-naphthalen-2-ylpropan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C21H23NO3
|
2
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
Ki = 410 nM
|
|
|
|
CP0542109
|
6-hydroxy-8-[1-hydroxy-2-[3-(3-methoxyphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H25ClN2O5
|
1
|
| 1 |
EC50 = 0.4266 nM
|
|
|
|
CP0418735
|
[1-[3-[3-chloro-4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]anilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C39H40ClN5O6
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0481431
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-2-methoxyanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O7
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0550010
|
[1-[2-[[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]benzoyl]amino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C39H41N5O6
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0479009
|
N-[4-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-2-methylpropanamide
Show/Hide
|
C24H29N3O4
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0534396
|
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-2-methylpropanamide
Show/Hide
|
C24H29N3O4
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0531757
|
6-hydroxy-8-[1-hydroxy-2-[(2-methyl-4,4-diphenylbutan-2-yl)amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C27H31ClN2O4
|
1
|
| 1 |
EC50 = 0.6166 nM
|
|
|
|
CP0547363
|
6-hydroxy-8-[1-hydroxy-2-[3-(3-methylphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H25ClN2O4
|
1
|
| 1 |
EC50 = 0.6918 nM
|
|
|
|
CP0468955
|
8-[2-[3-(4-fluorophenyl)propylamino]-1-hydroxyethyl]-6-hydroxy-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H22ClFN2O4
|
1
|
| 1 |
EC50 = 0.7413 nM
|
|
|
|
CP0010653
|
2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)
Show/Hide
|
C28H30N2O2
|
3
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
EC50 = 0.82 nM
|
|
|
| 3 |
Ki = 61 nM
|
|
|
|
CP0398267
|
[1-[3-[2-chloro-4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-5-methoxy-N-methylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H44ClN5O7
|
1
|
| 1 |
EC50 = 0.7943 nM
|
|
|
|
CP0418739
|
[1-[3-[3-[2-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]-4-methoxyanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O7
|
1
|
| 1 |
EC50 = 0.7943 nM
|
|
|
|
CP0531758
|
8-[2-[[4,4-bis(4-fluorophenyl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]-6-hydroxy-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C27H29ClF2N2O4
|
1
|
| 1 |
EC50 = 0.7943 nM
|
|
|
|
CP0571424
|
6-hydroxy-8-[1-hydroxy-2-[3-(4-hydroxyphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H23ClN2O5
|
1
|
| 1 |
EC50 = 0.8913 nM
|
|
|
|
CP0465673
|
(1R,2R,4S,5R,7S)-7-(2-Hydroxy-2,2-di-thiophen-2-yl-acetoxy)-9-{9-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-quinolin-5-yl)-ethylamino]-nonyl}-9-methyl-3-oxa-9-azonia-tricyclo[3.3.1.0*2,4*]nonane
Show/Hide
|
C38H48N3O7S2+
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
Ki = 36 nM
|
|
|
|
CP0571052
|
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-3-methylbutanamide
Show/Hide
|
C25H31N3O4
|
1
|
| 1 |
EC50 = 0.9333 nM
|
|
|
|
CP0526864
|
6-hydroxy-8-[1-hydroxy-2-[3-(4-methoxyphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H25ClN2O5
|
1
|
| 1 |
EC50 = 0.9333 nM
|
|
|
|
CP0405122
|
(R)-1-(7-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)heptyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C36H44N4O5
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0907537
|
(+/-)1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)nonyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C38H48N4O5
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0398269
|
[1-[3-[5-[2-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]-2-methoxyanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O7
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0392882
|
8-hydroxy-5-[(1S)-2-hydroxy-1-[2-(4-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O4
|
1
|
| 1 |
EC50 = 1.26 nM
|
|
|
|
CP0497884
|
(R)-1-(3-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)propyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C32H36N4O5
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0468958
|
6-hydroxy-8-[1-hydroxy-2-[3-[3-(trifluoromethyl)phenyl]propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H22ClF3N2O4
|
1
|
| 1 |
EC50 = 1.349 nM
|
|
|
|
CP0398268
|
[1-[2-[[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-3-methoxybenzoyl]amino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C40H43N5O7
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0514105
|
8-hydroxy-5-[2-hydroxy-1-(2-phenylethylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O3
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0542088
|
6-hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)ethylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C19H23ClN2O5
|
1
|
| 1 |
EC50 = 1.622 nM
|
|
|
|
CP0390139
|
5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)butan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C19H25NO4
|
2
|
| 1 |
EC50 = 1.63 nM
|
|
|
| 2 |
Ki = 420 nM
|
|
|
|
CP0432458
|
5-[1-[2-(2-chlorophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C19H19ClN2O3
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0459152
|
8-hydroxy-5-[2-hydroxy-1-[2-(3-methoxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0426737
|
(R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylaminopropane
Show/Hide
|
C18H23NO4
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Kd = 1950 nM
|
|
|
|
CP0547362
|
6-hydroxy-8-[1-hydroxy-2-[3-(4-methylphenyl)propylamino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C20H25ClN2O4
|
1
|
| 1 |
EC50 = 2.239 nM
|
|
|
|
CP0468953
|
6-hydroxy-8-[1-hydroxy-2-(2-phenylethylamino)ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C18H21ClN2O4
|
1
|
| 1 |
EC50 = 2.399 nM
|
|
|
|
CP0459150
|
5-[1-[2-(3-chlorophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C19H19ClN2O3
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0534395
|
N-[4-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-3,5,5-trimethylhexanamide
Show/Hide
|
C29H39N3O4
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0465671
|
(R)-1-(9-(2-(3-formamido-4-hydroxyphenyl)-2-hydroxyethylamino)nonyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C36H48N4O5
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
Ki = 21 nM
|
|
|
|
CP0383608
|
(R,S)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol
Show/Hide
|
C21H23NO3
|
2
|
| 1 |
EC50 = 2.7 nM
|
|
|
| 2 |
Kd = 339 nM
|
|
|
|
CP0443563
|
5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-hydroxyphenyl)butan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C18H23NO4
|
2
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
Ki = 1270 nM
|
|
|
|
CP0432459
|
8-hydroxy-5-[2-hydroxy-1-[2-(4-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O4
|
1
|
| 1 |
EC50 = 3.162 nM
|
|
|
|
CP0405121
|
2-((3S)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)nonyl)pyrrolidin-3-yl)-2,2-diphenylacetamide
Show/Hide
|
C38H48N4O4
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
|
CP0389037
|
5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxynaphthalen-1-yl)propan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C22H25NO4
|
2
|
| 1 |
EC50 = 3.9 nM
|
|
|
| 2 |
Ki = 280 nM
|
|
|
|
CP0380830
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-N,2-dimethylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O6
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0459151
|
N-[4-[2-[[2-hydroxy-1-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]phenyl]-2-phenylacetamide
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0415410
|
5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-methoxynaphthalen-1-yl)propan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C22H25NO4
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 320 nM
|
|
|
|
CP0432941
|
(R,S)-(-)-fenoterol
Show/Hide
|
C17H21NO4
|
2
|
| 1 |
EC50 = 4.7 nM
|
|
|
| 2 |
Kd = 3715 nM
|
|
|
|
CP0487585
|
8-[2-[2-(4-fluorophenyl)ethylamino]-1-hydroxyethyl]-6-hydroxy-4H-1,4-benzoxazin-3-one;hydrochloride
Show/Hide
|
C18H20ClFN2O4
|
1
|
| 1 |
EC50 = 4.898 nM
|
|
|
|
CP0392878
|
8-hydroxy-5-[2-hydroxy-1-[6-(4-phenylbutoxy)hexylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C27H36N2O4
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0432469
|
8-hydroxy-5-[2-hydroxy-1-[2-(2-methoxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0399132
|
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O5
|
2
|
| 1 |
EC50 = 6.2 nM
|
|
|
| 2 |
EC50 = 22 nM
|
|
|
|
CP0401112
|
5-hydroxy-8-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
2
|
| 1 |
EC50 = 7 nM
|
|
|
| 2 |
EC50 = 13 nM
|
|
|
|
CP0415409
|
(S,R)-(+)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylaminopropane
Show/Hide
|
C18H23NO4
|
1
|
| 1 |
EC50 = 7.2 nM
|
|
|
|
CP0486213
|
5-[(1R)-1-hydroxy-2-[[(2S)-1-naphthalen-2-ylpropan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C21H23NO3
|
2
|
| 1 |
EC50 = 7.6 nM
|
|
|
| 2 |
Ki = 510 nM
|
|
|
|
CP0438244
|
1-(biphenyl-2-yl)-3-(1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)nonyl)piperidin-4-yl)urea
Show/Hide
|
C38H49N5O4
|
2
|
| 1 |
EC50 = 8.4 nM
|
|
|
| 2 |
Ki = 115 nM
|
|
|
|
CP0478741
|
(S,R)-(+)-fenoterol
Show/Hide
|
C17H21NO4
|
3
|
| 1 |
EC50 = 8.5 nM
|
|
|
| 2 |
Kd = 10233 nM
|
|
|
| 3 |
Ki = 1828.1 nM
|
|
|
|
CP0480368
|
(3R)-3-(biphenyl-2-ylcarbamoyloxy)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)nonyl)-1-azoniabicyclo[2.2.2]octane
Show/Hide
|
C40H51N4O5+
|
2
|
| 1 |
EC50 = 8.9 nM
|
|
|
| 2 |
Ki = 123 nM
|
|
|
|
CP0436152
|
8-hydroxy-5-[1-hydroxy-2-(3-naphthalen-2-ylpropylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C24H24N2O3
|
1
|
| 1 |
EC50 = 9.12 nM
|
|
|
|
CP0392879
|
8-hydroxy-5-[2-hydroxy-1-[2-(2-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O4
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0471845
|
8-hydroxy-5-[2-hydroxy-1-(3-phenylpropylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0411419
|
5-[(1R)-1-hydroxy-2-[2-(4-methoxyphenyl)ethylamino]ethyl]benzene-1,3-diol
Show/Hide
|
C17H21NO4
|
2
|
| 1 |
EC50 = 10.19 nM
|
|
|
| 2 |
Ki = 2670 nM
|
|
|
|
CP0437060
|
(R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol
Show/Hide
|
C21H23NO3
|
2
|
| 1 |
EC50 = 12.5 nM
|
|
|
| 2 |
Kd = 240 nM
|
|
|
|
CP0508401
|
8-hydroxy-5-[2-hydroxy-1-(4-phenylbutylamino)ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
|
CP0381762
|
(R)-1-(9-(2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)nonyl)piperidin-4-yl biphenyl-2-ylcarbamate
Show/Hide
|
C36H49N3O5
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
Ki = 61 nM
|
|
|
|
CP0382024
|
5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-hydroxyphenyl)butan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C18H23NO4
|
2
|
| 1 |
EC50 = 16.6 nM
|
|
|
| 2 |
Ki = 5760 nM
|
|
|
|
CP0568302
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
|
C12H19BrClFN2O
|
1
|
| 1 |
EC50 = 19.42 nM
|
|
|
|
CP0473783
|
8-hydroxy-5-[2-hydroxy-1-[2-(4-methoxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0390136
|
(S,S)-(+)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylamino-propane
Show/Hide
|
C18H23NO4
|
1
|
| 1 |
EC50 = 33.2 nM
|
|
|
|
CP0389100
|
5-[1-[2-(4-chlorophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C19H19ClN2O3
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0418740
|
[1-[3-[4-[[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]methyl]-3-methoxy-N-methylanilino]-3-oxopropyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
Show/Hide
|
C41H45N5O7
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0392883
|
8-hydroxy-5-[2-hydroxy-1-[(2-methyl-1-phenylpropan-2-yl)amino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0514103
|
N-[4-[2-[[2-hydroxy-1-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]phenyl]benzamide
Show/Hide
|
C26H25N3O4
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0514104
|
N-[4-[2-[[2-hydroxy-1-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]phenyl]-2-methylpropanamide
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0462135
|
1-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]-3-phenylurea
Show/Hide
|
C26H28N4O3
|
1
|
| 1 |
EC50 = 52.21 nM
|
|
|
|
CP0970203
|
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol hydrochloride
Show/Hide
|
C13H19Cl2F3N2O
|
1
|
| 1 |
EC50 = 60.92 nM
|
|
|
|
CP0579213
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-(cyclopentylamino)ethanol;hydrochloride
Show/Hide
|
C13H19BrClFN2O
|
1
|
| 1 |
EC50 = 72.69 nM
|
|
|
|
CP0514102
|
5-[1-[2-(4-aminophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C19H21N3O3
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
|
CP0559126
|
N-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]-2-phenylacetamide
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
EC50 = 83.14 nM
|
|
|
|
CP0579365
|
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(cyclopentylamino)ethanol;hydrochloride
Show/Hide
|
C14H19BrClF3N2O
|
1
|
| 1 |
EC50 = 83.15 nM
|
|
|
|
CP0570407
|
2-amino-3-bromo-5-[1-(butylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
Show/Hide
|
C13H19BrClN3O
|
1
|
| 1 |
EC50 = 99.47 nM
|
|
|
|
CP0570404
|
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(butylamino)ethanol;hydrochloride
Show/Hide
|
C13H19Cl2F3N2O
|
1
|
| 1 |
EC50 = 102.8 nM
|
|
|
|
CP0467734
|
N-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]benzamide
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
EC50 = 117.8 nM
|
|
|
|
CP0384609
|
4-[(1R)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
2
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
EC50 = 210 nM
|
|
|
|
CP0576023
|
2-amino-3-bromo-5-[1-(cyclopentylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
Show/Hide
|
C14H19BrClN3O
|
1
|
| 1 |
EC50 = 142.3 nM
|
|
|
|
CP0578582
|
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[(2-methyl-1-phenylpropan-2-yl)amino]ethanol;hydrochloride
Show/Hide
|
C19H23Cl2F3N2O
|
1
|
| 1 |
EC50 = 143.8 nM
|
|
|
|
CP0422512
|
5-[(1S)-1-hydroxy-2-[2-(4-methoxyphenyl)ethylamino]ethyl]benzene-1,3-diol
Show/Hide
|
C17H21NO4
|
2
|
| 1 |
EC50 = 210 nM
|
|
|
| 2 |
Ki > 100000 nM
|
|
|
|
CP0570405
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-(propan-2-ylamino)ethanol;hydrochloride
Show/Hide
|
C11H17BrClFN2O
|
1
|
| 1 |
EC50 = 237.2 nM
|
|
|
|
CP0389099
|
8-hydroxy-5-[2-hydroxy-1-[4-(4-phenylbutoxy)butylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C25H32N2O4
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0384600
|
4-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
2
|
| 1 |
EC50 = 260 nM
|
|
|
| 2 |
EC50 = 5100 nM
|
|
|
|
CP0392554
|
N-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]-2-phenylacetamide
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
EC50 = 280.8 nM
|
|
|
|
CP0427807
|
N-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]benzamide
Show/Hide
|
C26H30N2O3
|
1
|
| 1 |
EC50 = 294.5 nM
|
|
|
|
CP0432487
|
5-[1-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C24H28N2O3
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0481819
|
8-hydroxy-5-[2-hydroxy-1-[2-(1H-indol-3-yl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0537346
|
N-[4-[2-[[2-hydroxy-1-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]phenyl]pentanamide
Show/Hide
|
C24H29N3O4
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0542414
|
8-hydroxy-5-[(1R)-2-hydroxy-1-[2-(4-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O4
|
1
|
| 1 |
EC50 = 328 nM
|
|
|
|
CP0574569
|
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(3-ethoxypropylamino)ethanol;hydrochloride
Show/Hide
|
C14H21Cl2F3N2O2
|
1
|
| 1 |
EC50 = 345.4 nM
|
|
|
|
CP0423699
|
N-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]benzenesulfonamide
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
EC50 = 353.1 nM
|
|
|
|
CP0579205
|
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(3-ethoxypropylamino)ethanol;hydrochloride
Show/Hide
|
C14H21BrClF3N2O2
|
1
|
| 1 |
EC50 = 370.1 nM
|
|
|
|
CP0569397
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-[(4-fluorophenyl)methylamino]ethanol;hydrochloride
Show/Hide
|
C15H16BrClF2N2O
|
1
|
| 1 |
EC50 = 398.8 nM
|
|
|
|
CP0569182
|
2-amino-3-bromo-5-[1-(3-ethoxypropylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
Show/Hide
|
C14H21BrClN3O2
|
1
|
| 1 |
EC50 = 440.2 nM
|
|
|
|
CP0415406
|
5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)pentan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C20H27NO4
|
2
|
| 1 |
EC50 = 462 nM
|
|
|
| 2 |
Ki = 7600 nM
|
|
|
|
CP0399136
|
8-hydroxy-5-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O5
|
2
|
| 1 |
EC50 = 510 nM
|
|
|
| 2 |
EC50 = 840 nM
|
|
|
|
CP0419868
|
5-hydroxy-8-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
2
|
| 1 |
EC50 = 580 nM
|
|
|
| 2 |
EC50 = 1000 nM
|
|
|
|
CP0579214
|
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(cyclopentylamino)ethanol;hydrochloride
Show/Hide
|
C14H19Cl2F3N2O
|
1
|
| 1 |
EC50 = 586.8 nM
|
|
|
|
CP0392880
|
5-[1-(2,2-diphenylethylamino)-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Show/Hide
|
C25H24N2O3
|
1
|
| 1 |
EC50 = 630.96 nM
|
|
|
|
CP0548003
|
N-[4-[2-[[2-hydroxy-1-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]phenyl]-3-methylbutanamide
Show/Hide
|
C24H29N3O4
|
1
|
| 1 |
EC50 = 630.96 nM
|
|
|
|
CP0399131
|
4-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
2
|
| 1 |
EC50 = 650 nM
|
|
|
| 2 |
EC50 = 2600 nM
|
|
|
|
CP0399135
|
4-[2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO4
|
1
|
| 1 |
EC50 = 720 nM
|
|
|
|
CP0462136
|
8-hydroxy-5-[2-hydroxy-1-[2-(3-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C19H20N2O4
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
|
|
CP0578584
|
2-amino-3-bromo-5-[1-(tert-butylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
Show/Hide
|
C13H19BrClN3O
|
1
|
| 1 |
EC50 = 852.9 nM
|
|
|
|
CP0427808
|
N-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]benzenesulfonamide
Show/Hide
|
C25H30N2O4S
|
1
|
| 1 |
EC50 = 954.3 nM
|
|
|
|
CP0382040
|
5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)butan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
|
C19H25NO4
|
2
|
| 1 |
EC50 = 1010 nM
|
|
|
| 2 |
Ki = 20100 nM
|
|
|
|
CP0550313
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-(3-ethoxypropylamino)ethanol;hydrochloride
Show/Hide
|
C13H21BrClFN2O2
|
1
|
| 1 |
EC50 = 1177 nM
|
|
|
|
CP0399134
|
4-[(1S)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
2
|
| 1 |
EC50 = 1400 nM
|
|
|
| 2 |
EC50 = 2200 nM
|
|
|
|
CP0467735
|
1-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]-3-phenylthiourea
Show/Hide
|
C26H31N3O2S
|
1
|
| 1 |
EC50 = 1419 nM
|
|
|
|
CP0569396
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-(butylamino)ethanol;hydrochloride
Show/Hide
|
C12H19BrClFN2O
|
1
|
| 1 |
EC50 = 1513 nM
|
|
|
|
CP0550314
|
2-(4-amino-3-bromo-5-fluorophenyl)-2-(cyclohexylamino)ethanol;hydrochloride
Show/Hide
|
C14H21BrClFN2O
|
1
|
| 1 |
EC50 = 1643 nM
|
|
|
|
CP0568301
|
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
|
C13H19BrClF3N2O
|
1
|
| 1 |
EC50 = 1855 nM
|
|
|
|
CP0545023
|
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(cyclohexylamino)ethanol;hydrochloride
Show/Hide
|
C15H21BrClF3N2O
|
1
|
| 1 |
EC50 = 2990 nM
|
|
|
|
CP0576022
|
2-(4-amino-3-nitrophenyl)-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
|
C12H20ClN3O3
|
1
|
| 1 |
EC50 = 3115 nM
|
|
|
|
CP0568229
|
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(butylamino)ethanol;hydrochloride
Show/Hide
|
C13H19BrClF3N2O
|
1
|
| 1 |
EC50 = 3163 nM
|
|
|
|
CP0578760
|
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(propan-2-ylamino)ethanol;hydrochloride
Show/Hide
|
C12H17BrClF3N2O
|
1
|
| 1 |
EC50 = 3349 nM
|
|
|
|
CP0462134
|
N-[4-[2-[[(2S)-3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]ethyl]phenyl]benzamide
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
EC50 = 6058 nM
|
|
|
|
CP0412172
|
5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)pentan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
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C20H27NO4
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2
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| 1 |
EC50 = 6100 nM
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| 2 |
Ki > 100000 nM
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CP0434094
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5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)-3-methylbutan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
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C20H27NO4
|
2
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| 1 |
EC50 = 6100 nM
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| 2 |
Ki > 100000 nM
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CP0579204
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2-(4-amino-3-fluoro-5-methylsulfonylphenyl)-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
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C13H22ClFN2O3S
|
1
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| 1 |
EC50 = 7239 nM
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CP0471977
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N-[[3-[(2S)-2-hydroxy-3-[2-[4-(phenylsulfamoylamino)phenyl]ethylamino]propoxy]phenyl]methyl]acetamide
Show/Hide
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C26H32N4O5S
|
1
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| 1 |
EC50 = 8433 nM
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CP0577936
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2-amino-3-bromo-5-[1-(cyclohexylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
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C15H21BrClN3O
|
1
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| 1 |
EC50 = 9241 nM
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CP0471844
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N-[[3-[(2S)-2-hydroxy-3-[2-[4-(phenylcarbamoylamino)phenyl]ethylamino]propoxy]phenyl]methyl]acetamide
Show/Hide
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C27H32N4O4
|
1
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| 1 |
EC50 = 9842 nM
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CP0058454
|
BA-679-BR
Show/Hide
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C19H22NO4S2+
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1
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| 1 |
EC50 > 10000 nM
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CP0543540
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2-[4-amino-3-(benzenesulfonyl)-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
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C19H24ClF3N2O3S
|
1
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| 1 |
EC50 > 10000 nM
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CP0570406
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2-(4-amino-3-bromo-5-fluorophenyl)-2-[(4-methoxyphenyl)methylamino]ethanol;hydrochloride
Show/Hide
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C16H19BrClFN2O2
|
1
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| 1 |
EC50 = 10000 nM
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CP0571821
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2-[4-amino-3-(benzenesulfonyl)-5-fluorophenyl]-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
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C18H24ClFN2O3S
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1
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| 1 |
EC50 > 10000 nM
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CP0579202
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2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]ethanol;hydrochloride
Show/Hide
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C22H27Cl2F3N2O
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1
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| 1 |
EC50 > 10000 nM
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CP0579206
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2-(4-amino-3-bromo-5-fluorophenyl)-2-(benzylamino)ethanol;hydrochloride
Show/Hide
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C15H17BrClFN2O
|
1
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| 1 |
EC50 = 10000 nM
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CP0579212
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2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(cyclohexylamino)ethanol;hydrochloride
Show/Hide
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C15H21Cl2F3N2O
|
1
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| 1 |
EC50 > 10000 nM
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CP0579364
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2-[4-amino-3-methylsulfonyl-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol;hydrochloride
Show/Hide
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C14H22ClF3N2O3S
|
1
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| 1 |
EC50 > 10000 nM
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CP0467736
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N-[4-[2-[[(2S)-3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]ethyl]phenyl]-2-phenylacetamide
Show/Hide
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C28H33N3O4
|
1
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| 1 |
EC50 = 15930 nM
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CP0440999
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N-[[3-[(2S)-3-[2-[4-(benzenesulfonamido)phenyl]ethylamino]-2-hydroxypropoxy]phenyl]methyl]acetamide
Show/Hide
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C26H31N3O5S
|
1
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| 1 |
EC50 = 23490 nM
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CP0426736
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5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)-3-methylbutan-2-yl]amino]ethyl]benzene-1,3-diol
Show/Hide
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C20H27NO4
|
2
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| 1 |
EC50 = 26200 nM
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| 2 |
Ki > 100000 nM
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CP0399133
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4-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
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C26H31NO4
|
1
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| 1 |
EC50 = 47000 nM
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CP0489921
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(2S)-1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
Show/Hide
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C15H23NO2
|
4
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| 1 |
IC50 = 0.7244 nM
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| 2 |
IC50 = 2.291 nM
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| 3 |
Kd = 0.8913 nM
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| 4 |
Ki = 0.9333 nM
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CP0062567
|
ALPRENOLOL,(+)
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C15H23NO2
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2
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| 1 |
IC50 = 1.148 nM
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| 2 |
IC50 = 5.495 nM
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CP0435169
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(2S)-1-[2-[3-[4-[[[1-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]propyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
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C36H55N9O4
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3
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| 1 |
IC50 = 1.202 nM
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| 2 |
IC50 = 2.884 nM
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| 3 |
Ki = 0.4365 nM
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CP0431930
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4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]ethyl]butanamide
Show/Hide
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C34H54N4O6
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4
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| 1 |
IC50 = 1.549 nM
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| 2 |
IC50 = 6.607 nM
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| 3 |
Kd = 1.288 nM
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| 4 |
Ki = 0.7586 nM
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CP0535807
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1,3-bis[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butyl]urea
Show/Hide
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C33H54N4O5
|
3
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| 1 |
IC50 = 1.585 nM
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| 2 |
IC50 = 1.778 nM
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| 3 |
Ki = 0.3802 nM
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CP0446703
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1,3-bis[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]urea
Show/Hide
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C31H50N4O5
|
4
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| 1 |
IC50 = 1.585 nM
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| 2 |
IC50 = 7.586 nM
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| 3 |
Kd = 1.905 nM
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| 4 |
Ki = 1.175 nM
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CP0552468
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1,3-bis[5-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]pentyl]urea
Show/Hide
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C35H58N4O5
|
1
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| 1 |
IC50 = 1.738 nM
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CP0435168
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(2S)-1-[2-[2-[4-[[[1-[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C34H51N9O4
|
3
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| 1 |
IC50 = 2.042 nM
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| 2 |
IC50 = 4.677 nM
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| 3 |
Ki = 0.8913 nM
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CP0440669
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1,3-bis[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethyl]urea
Show/Hide
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C29H46N4O5
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3
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| 1 |
IC50 = 2.188 nM
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| 2 |
IC50 = 16.22 nM
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| 3 |
Ki = 3.467 nM
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CP0476338
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(2S)-1-[2-[8-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]octyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
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C32H52N2O4
|
3
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| 1 |
IC50 = 2.344 nM
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| 2 |
IC50 = 5.248 nM
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| 3 |
Ki = 0.7943 nM
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CP0304390
|
(2R)-1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
Show/Hide
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C15H23NO2
|
3
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| 1 |
IC50 = 2.344 nM
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| 2 |
IC50 = 75.86 nM
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| 3 |
Ki = 18.2 nM
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CP0476337
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(2S)-1-[2-[6-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]hexyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C30H48N2O4
|
3
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| 1 |
IC50 = 3.236 nM
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| 2 |
IC50 = 3.802 nM
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| 3 |
Ki = 0.955 nM
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CP0431928
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3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoylamino]ethyl]propanamide
Show/Hide
|
C32H50N4O6
|
3
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| 1 |
IC50 = 3.311 nM
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| 2 |
IC50 = 75.86 nM
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| 3 |
Ki = 11.75 nM
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CP0540412
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(2S)-1-[2-[10-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]decyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C34H56N2O4
|
3
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| 1 |
IC50 = 3.802 nM
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| 2 |
IC50 = 13.8 nM
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| 3 |
Ki = 1.514 nM
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CP0554718
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N-[2-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]ethyl]-4-(2-methoxyphenyl)butanamide
Show/Hide
|
C29H43N3O5
|
1
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| 1 |
IC50 = 3.89 nM
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CP0508123
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N-[2-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]ethyl]-4-phenylbutanamide
Show/Hide
|
C28H41N3O4
|
1
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| 1 |
IC50 = 5.888 nM
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CP0446702
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(2S)-1-[2-[[4-[[[1-[[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]methyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]methyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C32H47N9O4
|
3
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| 1 |
IC50 = 6.31 nM
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| 2 |
IC50 = 64.57 nM
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| 3 |
Ki = 15.49 nM
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CP0508127
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4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[3-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]propyl]butanamide
Show/Hide
|
C35H56N4O6
|
1
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| 1 |
IC50 = 6.457 nM
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CP0476339
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(2S)-1-[2-[12-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]dodecyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C36H60N2O4
|
3
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| 1 |
IC50 = 6.918 nM
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| 2 |
IC50 = 25.7 nM
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| 3 |
Ki = 1.148 nM
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CP0535826
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3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[3-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoylamino]propyl]propanamide
Show/Hide
|
C33H52N4O6
|
1
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| 1 |
IC50 = 8.318 nM
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CP0554722
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4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[4-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]butyl]butanamide
Show/Hide
|
C36H58N4O6
|
1
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| 1 |
IC50 = 11.22 nM
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CP0435167
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(2S)-1-[2-[4-[[[1-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C30H43N9O4
|
3
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| 1 |
IC50 = 12.02 nM
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| 2 |
IC50 = 169.82 nM
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| 3 |
Ki = 38.9 nM
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CP0476809
|
1-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]-3-[3-(2-methoxyphenyl)propyl]urea
Show/Hide
|
C26H39N3O4
|
1
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| 1 |
IC50 = 13.8 nM
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CP0508121
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1-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]-3-(3-phenylpropyl)urea
Show/Hide
|
C25H37N3O3
|
1
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| 1 |
IC50 = 14.13 nM
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CP0113242
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(2S)-1-[2-[2-[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenoxy]ethoxy]ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C28H44N2O7
|
1
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| 1 |
IC50 = 46.77 nM
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CP0535795
|
N-[2-(butanoylamino)ethyl]-4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
Show/Hide
|
C22H37N3O4
|
1
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| 1 |
IC50 = 64.57 nM
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CP0541127
|
(2S)-1-[2-[2-[2-[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenoxy]ethoxy]ethoxy]ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Show/Hide
|
C30H48N2O8
|
1
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| 1 |
IC50 = 74.13 nM
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CP0508122
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1-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]-3-propylurea
Show/Hide
|
C19H33N3O3
|
1
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| 1 |
IC50 = 85.11 nM
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CP0535827
|
4-[2-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[4-[2-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]ethyl]butanamide
Show/Hide
|
C34H54N4O6
|
1
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| 1 |
IC50 = 213.8 nM
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CP0435173
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2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetyl]amino]ethyl]acetamide
Show/Hide
|
C30H46N4O6
|
3
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| 1 |
IC50 = 213.8 nM
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| 2 |
IC50 = 2630.27 nM
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| 3 |
Ki = 467.74 nM
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CP0377739
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[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-(dithiolan-3-yl)pentanoate
Show/Hide
|
C27H33NO2S2
|
1
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| 1 |
IC50 > 10000 nM
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CP0041757
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1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Show/Hide
|
C24H26N2O4
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1
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| 1 |
Kd = 0.195 nM
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CP0383607
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(S,R)-(+)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol
Show/Hide
|
C21H23NO3
|
1
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| 1 |
Kd = 1778 nM
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CP0527243
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(R,R)-4
Show/Hide
|
C17H22N2O3
|
1
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| 1 |
Kd = 1862 nM
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CP0491618
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(S,S)-(+)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol
Show/Hide
|
C21H23NO3
|
1
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| 1 |
Kd = 2512 nM
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CP0383613
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(R,R)-(-)-5-{2-[2-(4-aminophenyl)-1-methylethylamino]-1-hydroxyethyl}-1,3-benzenediol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Kd = 2951 nM
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CP0539115
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(S,R)-2
Show/Hide
|
C18H23NO4
|
1
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| 1 |
Kd = 5248 nM
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CP0539408
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(R,S)-4
Show/Hide
|
C17H22N2O3
|
1
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| 1 |
Kd = 6026 nM
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CP0412061
|
(R,S)-(-)-5-{2-[2-(4-aminophenyl)-1-methylethylamino]-1-hydroxyethyl}-1,3-benzenediol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Kd = 7943 nM
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CP0518630
|
(R,R)- 6
Show/Hide
|
C15H25NO3
|
1
|
| 1 |
Kd = 9333 nM
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CP0394134
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(R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-benzenediol
Show/Hide
|
C16H19NO3
|
1
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| 1 |
Kd = 10471 nM
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|
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CP0555568
|
(S,S)- 2
Show/Hide
|
C18H23NO4
|
1
|
| 1 |
Kd = 15849 nM
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CP0496886
|
(S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-benzenediol
Show/Hide
|
C16H19NO3
|
1
|
| 1 |
Kd = 20417 nM
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CP0383611
|
(S,R)-(+)-5-{2-[2-(4-aminophenyl)-1-methylethylamino]-1-hydroxyethyl}-1,3-benzenediol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Kd = 22909 nM
|
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|
|
CP0044680
|
(S,S)-(+)-fenoterol
Show/Hide
|
C17H21NO4
|
2
|
| 1 |
Kd = 27542 nM
|
|
|
| 2 |
Ki = 3372.87 nM
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CP0394137
|
(S,S)-(+)-5-{2-[2-(4-aminophenyl)-1-methylethylamino]-1-hydroxyethyl}-1,3-benzenediol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Kd = 28840 nM
|
|
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CP0561012
|
(S,S)- 4
Show/Hide
|
C17H22N2O3
|
1
|
| 1 |
Kd = 28840 nM
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|
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CP0483037
|
(S,R)- 4
Show/Hide
|
C17H22N2O3
|
1
|
| 1 |
Kd = 30903 nM
|
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CP0539839
|
(R,S)-6
Show/Hide
|
C15H25NO3
|
1
|
| 1 |
Kd = 31623 nM
|
|
|
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CP0526427
|
(S,S)-6
Show/Hide
|
C15H25NO3
|
1
|
| 1 |
Kd = 56234 nM
|
|
|
|
CP0516281
|
(S,R)- 6
Show/Hide
|
C15H25NO3
|
1
|
| 1 |
Kd = 100000 nM
|
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|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
2
|
| 1 |
Ki = 0.46 nM
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|
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| 2 |
Ki = 3.69 nM
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CP0041553
|
5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamino)ethyl)benzene-1,3-diol
Show/Hide
|
C17H21NO4
|
1
|
| 1 |
Ki = 126 nM
|
|
|
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CP0116478
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1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C24H30N2O
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1
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| 1 |
Ki = 9549.93 nM
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CP0635067
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2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
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C8H9Cl2N3
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1
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| 1 |
Ki > 10000 nM
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CP0232093
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1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C22H27N3O
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1
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| 1 |
Ki = 35481.34 nM
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CP0232092
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1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C21H32N2O
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1
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| 1 |
Ki = 43651.58 nM
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