Brief Information of the Compound and Protein
Compound Name
5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-hydroxyphenyl)butan-2-yl]amino]ethyl]benzene-1,3-diol
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PubChem ID
CID: 53380559
SID: 125303140
Canonical SMILES
CC[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
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Compound Formula C18H23NO4
Compound Structure
Protein Name
Beta-2 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Adrenergic receptor
Uniprot ID
P07550
Gene Name
ADRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 2.8 nM
   TI
   LI
   LO
   TS
2
Ki = 1270 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 1.44 nM
   TI
   LI
   LO
   TS