Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)
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 PubChem ID
CID: 444031
SID: 14856314
Canonical SMILES
NC(=O)C([C@@H]1CCN(CCc2ccc3OCCc3c2)C1)(c1ccccc1)c1ccccc1
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Compound Formula C28H30N2O2
Compound Structure
Protein Name
 Protein Info 
Beta-2 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P07550
Gene Name
ADRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 0.7943 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.82 nM
   TI
   LI
   LO
   TS
3
Ki = 61 nM
   TI
   LI
   LO
   TS
CL000246 NCI-H292
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 15.9 nM