Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride
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 PubChem ID
CID: 3779
SID: 14748912
Canonical SMILES
CC(C)NCC(O)c1ccc(O)c(O)c1
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Compound Formula C11H17NO3
Compound Structure
Protein Name
 Protein Info 
Beta-2 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P07550
Gene Name
ADRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  9
1
EC50 = 0.1585 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.84 nM
   TI
   LI
   LO
   TS
3
EC50 = 2 nM
   TI
   LI
   LO
   TS
4
EC50 = 3 nM
   TI
   LI
   LO
   TS
5
EC50 = 13 nM
   TI
   LI
   LO
   TS
6
EC50 = 39.81 nM
   TI
   LI
   LO
   TS
7
Kd = 740 nM
   TI
   LI
   LO
   TS
8
Ki = 46 nM
   TI
   LI
   LO
   TS
9
Ki = 676.08 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
EC50 = 0.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.2138 nM
   TI
   LI
   LO
   TS
3
EC50 = 0.3162 nM
   TI
   LI
   LO
   TS
4
EC50 = 5.954 nM
   TI
   LI
   LO
   TS
5
EC50 = 87 nM
   TI
   LI
   LO
   TS
6
EC50 = 120 nM
   TI
   LI
   LO
   TS
7
Ki = 2.44 nM
   TI
   LI
   LO
   TS
8
Ki = 192 nM
   TI
   LI
   LO
   TS
CL000246 NCI-H292
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 50 nM
2 Kd = 251.19 nM