Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_73573-87-2
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 PubChem ID
CID: 3410
SID: 14875897
Canonical SMILES
COc1ccc(CC(C)NCC(O)c2ccc(O)c(NC=O)c2)cc1
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Compound Formula C19H24N2O4
Compound Structure
Protein Name
 Protein Info 
Beta-2 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P07550
Gene Name
ADRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000612 BEAS-2B
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2.512 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 0.5012 nM
   TI
   LI
   LO
   TS
2
Ki = 2.6 nM
   TI
   LI
   LO
   TS
3
Ki = 23 nM
   TI
   LI
   LO
   TS
4
Ki = 26 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.4 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 0.19 nM
   TI
   LI
   LO
   TS
2
Ki = 33 nM
   TI
   LI
   LO
   TS
CL000246 NCI-H292
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 0.5012 nM
   TI
   LI
   LO
   TS
2
EC50 = 1 nM
   TI
   LI
   LO
   TS
3
EC50 = 2.512 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 2.512 nM
2 Ki = 2.6 nM