| Compound ID |
Compound Name |
Compound Formula |
|
CP0575628
|
6-[3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-3-fluoro-8-azabicyclo[3.2.1]octan-8-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C32H31F4N3O5
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0560061
|
6-[3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-3-fluoro-8-azabicyclo[3.2.1]octan-8-yl]-1-ethylindole-3-carboxylic acid
Show/Hide
|
C33H33F4N3O5
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0556789
|
6-[3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-3-fluoro-8-azabicyclo[3.2.1]octan-8-yl]-1-benzothiophene-3-carboxylic acid
Show/Hide
|
C31H28F4N2O5S
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0361692
|
6-[4-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzothiophene-3-carboxylic acid
Show/Hide
|
C29H26F4N2O5S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0444792
|
6-[4-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C30H29F4N3O5
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0444793
|
6-[4-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-ethylindole-3-carboxylic acid
Show/Hide
|
C31H31F4N3O5
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0093217
|
3-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H22Cl2F3N3O4
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 9 nM
|
|
|
|
CP0494729
|
propan-2-yl 2-cyano-6-(3-fluorobenzoyl)-4,4-dimethyl-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C22H22FN3O3
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0575626
|
2-[4-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C28H24F5N3O5S
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0205327
|
5-[(1R,2R)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]-1-propan-2-ylpyrazole-3-carboxylic acid
Show/Hide
|
C29H26Cl3N3O4
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0177105
|
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C28H27Cl2N3O4
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0528450
|
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-ethylindole-2-carboxylic acid
Show/Hide
|
C30H30Cl2FN3O4
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0373756
|
propan-2-yl 2-cyano-6-(4-fluorobenzoyl)-4,4-dimethyl-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C22H22FN3O3
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0560040
|
6-[4-[[3-(2-chloro-6-fluorophenyl)-5-cyclopropyl-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C29H28ClF2N3O4
|
1
|
| 1 |
EC50 = 5.2 nM
|
|
|
|
CP0534085
|
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C29H28Cl2FN3O4
|
1
|
| 1 |
EC50 = 5.8 nM
|
|
|
|
CP0035667
|
3-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H24Cl2F3N3O4
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
EC50 = 80 nM
|
|
|
|
CP0195439
|
4-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H22Cl2F3N3O4
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
EC50 = 30 nM
|
|
|
|
CP0234484
|
5-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]-1-propan-2-ylpyrazole-3-carboxylic acid
Show/Hide
|
C29H26Cl3N3O4
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0388303
|
propan-2-yl 2-cyano-6-(3,4-difluorobenzoyl)-4,4-dimethyl-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C22H21F2N3O3
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0494730
|
propan-2-yl 2-cyano-6-(cyclohexanecarbonyl)-4,4-dimethyl-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0564199
|
2-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C28H22Cl2FN3O3S
|
1
|
| 1 |
EC50 = 7.1 nM
|
|
|
|
CP0361691
|
6-[4-[[3-(2-chloro-6-fluorophenyl)-5-cyclopropyl-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-ethylindole-3-carboxylic acid
Show/Hide
|
C30H30ClF2N3O4
|
1
|
| 1 |
EC50 = 7.6 nM
|
|
|
|
CP0397108
|
propan-2-yl 2-cyano-4,4-dimethyl-6-[3-(trifluoromethyl)benzoyl]-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
EC50 = 8.5 nM
|
|
|
|
CP0177108
|
2-[3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-3-fluoro-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C30H26F5N3O5S
|
1
|
| 1 |
EC50 = 8.7 nM
|
|
|
|
CP0568396
|
2-[4-[(E)-2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]ethenyl]piperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C27H22Cl2FN3O3S
|
1
|
| 1 |
EC50 = 10.5 nM
|
|
|
|
CP0233703
|
4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)-N-(methylsulfonyl)benzamide
Show/Hide
|
C29H27Cl2F3N4O5S
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
EC50 = 221 nM
|
|
|
|
CP0444796
|
2-[4-[[3-(2-chloro-6-fluorophenyl)-5-cyclopropyl-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C27H23ClF3N3O4S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0397105
|
propan-2-yl 6-(3-chlorobenzoyl)-2-cyano-4,4-dimethyl-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C22H22ClN3O3
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0089615
|
3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
Show/Hide
|
C28H22Cl3NO4
|
5
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 26 nM
|
|
|
| 3 |
EC50 = 30 nM
|
|
|
| 4 |
EC50 = 35 nM
|
|
|
| 5 |
EC50 = 70 nM
|
|
|
|
CP0573619
|
2-[2-[5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C29H23F4N3O3S
|
1
|
| 1 |
EC50 = 13.8 nM
|
|
|
|
CP0065418
|
5-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]pyridine-3-carboxylic acid
Show/Hide
|
C28H21Cl3N2O4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0419306
|
6-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]-1-methylindazole-3-carboxylic acid
Show/Hide
|
C31H24Cl3N3O4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0060594
|
WAY-362450
Show/Hide
|
C25H24F2N2O3
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
EC50 = 16 nM
|
|
|
|
CP0035660
|
4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H24Cl2F3N3O4
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
EC50 = 90 nM
|
|
|
|
CP0140040
|
CHEMBL3822859
Show/Hide
|
C30H24Cl3NO4
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0430979
|
propan-2-yl 2-cyano-4,4-dimethyl-6-(thiophene-2-carbonyl)-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C20H21N3O3S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0288384
|
3-(4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)phenyl)propanoic acid
Show/Hide
|
C30H28Cl2F3N3O4
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
EC50 = 35 nM
|
|
|
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CP0035669
|
2-(4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)phenoxy)acetic acid
Show/Hide
|
C29H26Cl2F3N3O5
|
2
|
| 1 |
EC50 = 19 nM
|
|
|
| 2 |
EC50 = 214 nM
|
|
|
|
CP0093218
|
3-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)-N-(methylsulfonyl)benzamide
Show/Hide
|
C29H27Cl2F3N4O5S
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
EC50 = 279 nM
|
|
|
|
CP0177104
|
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzofuran-3-carboxylic acid
Show/Hide
|
C28H25Cl2FN2O5
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0444707
|
2-[4-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]ethyl]piperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C27H24Cl2FN3O3S
|
1
|
| 1 |
EC50 = 21.4 nM
|
|
|
|
CP0452273
|
propan-2-yl 1,1-dimethyl-3-[4-(morpholin-4-ylmethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
|
C30H35N3O4
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0569838
|
2-[2-[5-cyclopropyl-3-(3,5-dichloropyridin-4-yl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C27H21Cl2FN4O3S
|
1
|
| 1 |
EC50 = 24.6 nM
|
|
|
|
CP0468004
|
3-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxycyclobutyl]benzoic acid
Show/Hide
|
C30H24Cl3NO5
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0564620
|
CHEMBL5202191
Show/Hide
|
C35H44FN3O4
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0579166
|
ethyl 4-[3-[cyclohexanecarbonyl-[[4-(2-methoxy-1,3-oxazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]-1,3-thiazole-2-carboxylate
Show/Hide
|
C32H39N3O5S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0568285
|
methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
|
C31H39N3O4
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0191249
|
3-[(1R,2R)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoic acid
Show/Hide
|
C29H22Cl3NO4
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0575801
|
US11254663, Example 119
Show/Hide
|
C32H38FN5O3
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0444709
|
6-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]pyridine-3-carboxylic acid
Show/Hide
|
C26H23Cl2N3O3
|
1
|
| 1 |
EC50 = 30.5 nM
|
|
|
|
CP0093216
|
3-((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)methoxy)benzoic acid
Show/Hide
|
C27H19Cl2F3N2O5
|
2
|
| 1 |
EC50 = 33 nM
|
|
|
| 2 |
EC50 = 151 nM
|
|
|
|
CP0131381
|
3-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoic acid
Show/Hide
|
C29H22Cl3NO4
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0550462
|
CHEMBL5182534
Show/Hide
|
C35H41F4N3O4
|
2
|
| 1 |
EC50 = 34 nM
|
|
|
| 2 |
EC50 = 42 nM
|
|
|
|
CP0457518
|
propan-2-yl 2-cyano-6-(4-cyanobenzoyl)-4,4-dimethyl-1,5-dihydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
|
C23H22N4O3
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0552428
|
6-[4-[[5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C30H29F4N3O4
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0560190
|
6-[4-[[3-(2-chlorophenyl)-5-cyclopropyl-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C29H29ClFN3O4
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0269600
|
4-((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)methoxy)benzoic acid
Show/Hide
|
C27H19Cl2F3N2O5
|
2
|
| 1 |
EC50 = 38 nM
|
|
|
| 2 |
EC50 = 95 nM
|
|
|
|
CP0573001
|
N-[[4-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(2-ethoxypyrimidin-5-yl)phenyl]-3-fluorobicyclo[1.1.1]pentane-1-carboxamide
Show/Hide
|
C33H40FN5O3
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0205326
|
4-[(1R,2R)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]-N-methylsulfonylbenzamide
Show/Hide
|
C30H25Cl3N2O5S
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0223207
|
4-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]-N-methylsulfonylbenzamide
Show/Hide
|
C30H25Cl3N2O5S
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0543710
|
N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]cyclohexanecarboxamide
Show/Hide
|
C32H39N5O3
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0426925
|
propan-2-yl 3-(3,4-difluorobenzoyl)-9-fluoro-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
|
C25H23F3N2O3
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0549038
|
6-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-1-methylindole-3-carboxylic acid
Show/Hide
|
C30H27Cl2N3O3
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0550455
|
US11254663, Example 157
Show/Hide
|
C32H38FN5O3
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0131383
|
4-[(1R,2R)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoic acid
Show/Hide
|
C29H22Cl3NO4
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0570891
|
6-[4-[[5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzothiophene-3-carboxylic acid
Show/Hide
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C29H26F4N2O4S
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1
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| 1 |
EC50 = 47 nM
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CP0571533
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2-[2-[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
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C29H23F4N3O4S
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1
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| 1 |
EC50 = 49.5 nM
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CP0191251
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CHEMBL3822477
Show/Hide
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C32H26Cl3N3O5
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1
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| 1 |
EC50 = 50 nM
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CP0545451
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6-[2-[5-cyclopropyl-3-(3,5-dichloropyridin-4-yl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-(trifluoromethyl)quinoline-2-carboxylic acid
Show/Hide
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C30H23Cl2F3N4O3
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3
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| 1 |
EC50 = 53 nM
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| 2 |
EC50 = 53.1 nM
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| 3 |
EC50 = 351 nM
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CP0181876
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5-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]pyridine-2-carboxylic acid
Show/Hide
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C28H21Cl3N2O4
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1
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| 1 |
EC50 = 57 nM
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CP0578326
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methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-(3-methyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
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C29H37N3O4
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1
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| 1 |
EC50 = 57 nM
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CP0270328
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3-(1-(6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)ethoxy)benzoic acid
Show/Hide
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C28H21Cl2F3N2O5
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2
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| 1 |
EC50 = 58 nM
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| 2 |
EC50 = 107 nM
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CP0570355
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(5-ethoxy-1,2-oxazol-3-yl)phenyl]cyclohexanecarboxamide
Show/Hide
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C32H40N4O4
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1
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| 1 |
EC50 = 59 nM
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CP0553908
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6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-ethylindole-3-carboxylic acid
Show/Hide
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C30H30Cl2FN3O4
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1
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| 1 |
EC50 = 60 nM
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CP0093219
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3-(((3-chloro-5-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)pyridin-2-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
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C27H24Cl3N3O4
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2
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| 1 |
EC50 = 61 nM
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| 2 |
EC50 = 100 nM
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CP0324046
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4-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxycyclobutyl]benzoic acid
Show/Hide
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C30H24Cl3NO5
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1
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| 1 |
EC50 = 63 nM
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CP0549042
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6-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]quinoline-2-carboxylic acid
Show/Hide
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C30H25Cl2N3O3
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1
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| 1 |
EC50 = 63 nM
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CP0177106
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6-[4-[[5-cyclopropyl-3-(2-fluorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
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C29H29F2N3O4
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1
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| 1 |
EC50 = 65 nM
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CP0564621
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methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-[4-(dimethylamino)phenyl]-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
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C34H44N2O3
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1
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| 1 |
EC50 = 66 nM
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CP0575452
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N-[[4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]-3-fluorobicyclo[1.1.1]pentane-1-carboxamide
Show/Hide
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C32H38FN5O3
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1
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| 1 |
EC50 = 70 nM
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CP0197641
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4-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoic acid
Show/Hide
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C29H22Cl3NO4
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1
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| 1 |
EC50 = 76 nM
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CP0181869
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3-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxyazetidin-1-yl]benzoic acid
Show/Hide
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C29H23Cl3N2O5
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1
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| 1 |
EC50 = 86 nM
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CP0046292
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1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morpholin-4-ylpropoxy)phenyl]carbonyl}-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H38FN3O5
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1
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| 1 |
EC50 = 88 nM
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CP0424372
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3-[(1S,2S)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoic acid
Show/Hide
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C29H22Cl3NO4
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1
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| 1 |
EC50 = 90 nM
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CP0197639
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3-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclobutyl]benzoic acid
Show/Hide
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C30H24Cl3NO4
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1
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| 1 |
EC50 = 92 nM
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CP0564549
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-methoxyphenyl)phenyl]cyclohexanecarboxamide
Show/Hide
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C34H41N3O3
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1
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| 1 |
EC50 = 92 nM
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CP0564619
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]-3-fluorobicyclo[1.1.1]pentane-1-carboxamide
Show/Hide
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C31H34FN5O3
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1
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| 1 |
EC50 = 93 nM
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CP0575799
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(2-methoxypyridin-4-yl)phenyl]cyclohexanecarboxamide
Show/Hide
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C33H40N4O3
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1
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| 1 |
EC50 = 95 nM
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CP0560188
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6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzothiophene-3-carboxylic acid
Show/Hide
|
C28H25Cl2FN2O4S
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1
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| 1 |
EC50 = 96 nM
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CP0290323
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propan-2-yl 8-fluoro-1,1-dimethyl-3-[4-(2-morpholin-4-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
|
C31H36FN3O5
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1
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| 1 |
EC50 = 99 nM
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CP0573395
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6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]naphthalene-2-carboxylic acid
Show/Hide
|
C30H27Cl2FN2O4
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1
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| 1 |
EC50 = 100 nM
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CP0046293
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propan-2-yl 1,1-dimethyl-3-[4-(3-morpholin-4-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H39N3O5
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1
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| 1 |
EC50 = 101 nM
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CP0093213
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4-((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-ylamino)methyl)benzoic acid
Show/Hide
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C27H22Cl2F3N3O4
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2
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| 1 |
EC50 = 101 nM
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| 2 |
EC50 = 398 nM
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CP0191250
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3-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-methoxycyclobutyl]benzoic acid
Show/Hide
|
C31H26Cl3NO5
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1
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| 1 |
EC50 = 102 nM
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CP0569416
|
US11254663, Example 440
Show/Hide
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C34H41FN4O3
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1
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| 1 |
EC50 = 104 nM
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CP0270326
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4-(((3-chloro-5-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)pyridin-2-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
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C27H24Cl3N3O4
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2
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| 1 |
EC50 = 107 nM
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| 2 |
EC50 = 120 nM
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CP0191263
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5-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxycyclobutyl]-1-propan-2-ylpyrazole-3-carboxylic acid
Show/Hide
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C30H28Cl3N3O5
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1
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| 1 |
EC50 = 110 nM
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CP0140039
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4-[[3-chloro-4-[2-[6-(2H-tetrazol-5-yl)pyridin-3-yl]cyclopropyl]phenoxy]methyl]-5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazole
Show/Hide
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C28H21Cl3N6O2
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1
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| 1 |
EC50 = 111 nM
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CP0564618
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methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-(4-cyclopropylphenyl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
|
C35H43NO3
|
1
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| 1 |
EC50 = 111 nM
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CP0569151
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N-[[4-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(2-ethoxypyrimidin-5-yl)phenyl]-3-hydroxy-3-methylcyclobutane-1-carboxamide
Show/Hide
|
C33H43N5O4
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1
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| 1 |
EC50 = 111 nM
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CP0195442
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4-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(ethyl)amino)methyl)benzoic acid
Show/Hide
|
C29H24Cl2F3N3O4
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2
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| 1 |
EC50 = 113 nM
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| 2 |
EC50 = 180 nM
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CP0543712
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]oxane-4-carboxamide
Show/Hide
|
C31H37N5O4
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1
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| 1 |
EC50 = 114 nM
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CP0543708
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methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-(4-morpholin-4-ylphenyl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
|
C36H46N2O4
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1
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| 1 |
EC50 = 118 nM
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CP0569486
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2-[6-[(E)-2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]ethenyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C27H20Cl2FN3O3S
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1
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| 1 |
EC50 = 120 nM
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CP0444794
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2-[4-[[3-(2-chlorophenyl)-5-cyclopropyl-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
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C27H24ClF2N3O4S
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1
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| 1 |
EC50 = 140 nM
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CP0562192
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6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzothiophene-2-carboxylic acid
Show/Hide
|
C28H25Cl2FN2O4S
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1
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| 1 |
EC50 = 140 nM
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CP0543709
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methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-(4-methoxyphenyl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
|
C33H41NO4
|
1
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| 1 |
EC50 = 142 nM
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CP0577892
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]-4,4-difluorocyclohexane-1-carboxamide
Show/Hide
|
C32H37F2N5O3
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1
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| 1 |
EC50 = 149 nM
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CP0569417
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N-[[4-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(2-ethoxypyrimidin-5-yl)phenyl]-3-hydroxy-3-(trifluoromethyl)cyclobutane-1-carboxamide
Show/Hide
|
C33H40F3N5O4
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1
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| 1 |
EC50 = 152 nM
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CP0578821
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methyl (E)-3-[3-[[4-[4-(azetidin-1-yl)phenyl]-1-bicyclo[2.2.2]octanyl]methyl-(cyclohexanecarbonyl)amino]phenyl]prop-2-enoate
Show/Hide
|
C35H44N2O3
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1
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| 1 |
EC50 = 152 nM
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CP0289782
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2-(4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)phenoxy)ethanol
Show/Hide
|
C29H28Cl2F3N3O4
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2
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| 1 |
EC50 = 155 nM
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| 2 |
EC50 = 1150 nM
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CP0568868
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N-[[4-[5-(difluoromethyl)-1,2,4-oxadiazol-3-yl]-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(2-ethoxypyrimidin-5-yl)phenyl]-3-fluorobicyclo[1.1.1]pentane-1-carboxamide
Show/Hide
|
C30H32F3N5O3
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1
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| 1 |
EC50 = 170 nM
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CP0444791
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4-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]benzoic acid
Show/Hide
|
C26H25Cl2FN2O4
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1
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| 1 |
EC50 = 180 nM
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CP0560192
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2-[4-[[5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C28H24F5N3O4S
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1
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| 1 |
EC50 = 180 nM
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CP0194602
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4-((1-(6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)ethyl)(methyl)amino)benzoic acid
Show/Hide
|
C29H24Cl2F3N3O4
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2
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| 1 |
EC50 = 182 nM
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| 2 |
EC50 = 208 nM
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CP0197637
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4-[(1S,2S)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoic acid
Show/Hide
|
C29H22Cl3NO4
|
1
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| 1 |
EC50 = 186 nM
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CP0310573
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4-(1-(6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)ethoxy)benzoic acid
Show/Hide
|
C28H21Cl2F3N2O5
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2
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| 1 |
EC50 = 189 nM
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| 2 |
EC50 = 611 nM
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CP0514346
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propan-2-yl 1,1-dimethyl-3-[4-[3-(4-methylpiperazin-1-yl)propoxy]benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
|
C33H42N4O4
|
1
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| 1 |
EC50 = 194 nM
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CP0195445
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4-(1-(6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)ethylamino)benzoic acid
Show/Hide
|
C28H22Cl2F3N3O4
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2
|
| 1 |
EC50 = 202 nM
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| 2 |
EC50 = 333 nM
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CP0549037
|
2-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]nonan-7-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C28H24Cl2FN3O3S
|
1
|
| 1 |
EC50 = 202 nM
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CP0361928
|
6-[2-[5-cyclopropyl-3-(3,5-dichloropyridin-4-yl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]quinoline-2-carboxylic acid
Show/Hide
|
C29H24Cl2N4O3
|
1
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| 1 |
EC50 = 206 nM
|
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CP0288386
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4-((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)carbamoyl)benzoic acid
Show/Hide
|
C28H22Cl2F3N3O5
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2
|
| 1 |
EC50 = 208 nM
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| 2 |
EC50 = 316 nM
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CP0197638
|
2-[[4-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoyl]amino]acetic acid
Show/Hide
|
C31H25Cl3N2O5
|
1
|
| 1 |
EC50 = 209 nM
|
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CP0093214
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2-(3-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzamido)ethyl dihydrogen phosphate
Show/Hide
|
C30H30Cl2F3N4O7P
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2
|
| 1 |
EC50 = 216 nM
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| 2 |
EC50 = 457 nM
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CP0197640
|
CHEMBL3823688
Show/Hide
|
C32H28Cl3NO5
|
1
|
| 1 |
EC50 = 220 nM
|
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CP0517090
|
2-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-1,3-dioxa-8-azaspiro[4.5]decan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
|
C27H22Cl2FN3O5S
|
1
|
| 1 |
EC50 = 227 nM
|
|
|
|
CP0575800
|
US11254663, Example 10
Show/Hide
|
C30H33F2N5O3
|
1
|
| 1 |
EC50 = 228 nM
|
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CP0553909
|
6-[4-[[5-cyclopropyl-3-(2-fluorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzothiophene-3-carboxylic acid
Show/Hide
|
C28H26F2N2O4S
|
1
|
| 1 |
EC50 = 230 nM
|
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CP0569192
|
N-[[4-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-1-bicyclo[2.2.2]octanyl]methyl]-3-fluoro-N-[3-(4-hydroxypiperidin-1-yl)phenyl]bicyclo[1.1.1]pentane-1-carboxamide
Show/Hide
|
C30H37F3N4O3
|
1
|
| 1 |
EC50 = 232 nM
|
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CP0060593
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propan-2-yl 1,1-dimethyl-3-[4-(2-morpholin-4-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H37N3O5
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1
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| 1 |
EC50 = 249 nM
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CP0552430
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2-[4-[[5-cyclopropyl-3-(2-fluorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
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C27H24F3N3O4S
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1
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| 1 |
EC50 = 270 nM
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CP0383870
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propan-2-yl 3-[4-[3-(dimethylamino)propoxy]benzoyl]-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C30H37N3O4
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1
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| 1 |
EC50 = 271 nM
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CP0397106
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propan-2-yl 2-cyano-6-(3,4-difluorobenzoyl)-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
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C22H23F2N3O3
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1
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| 1 |
EC50 = 280 nM
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CP0387463
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propan-2-yl 1,1-dimethyl-3-[4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H40N4O4
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1
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| 1 |
EC50 = 287 nM
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CP0568284
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methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-(4-pyrrolidin-1-ylphenyl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]prop-2-enoate
Show/Hide
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C36H46N2O3
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1
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| 1 |
EC50 = 299 nM
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CP0570890
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2-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1,3-benzothiazole-5-carboxylic acid
Show/Hide
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C27H24Cl2FN3O4S
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1
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| 1 |
EC50 = 330 nM
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CP0417880
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propan-2-yl 1,1-dimethyl-3-[3-(pyrrolidin-1-ylmethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C30H35N3O3
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1
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| 1 |
EC50 = 340 nM
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CP0492781
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propan-2-yl 8-fluoro-1,1-dimethyl-3-[4-(2-morpholin-4-ylethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H36FN3O4
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1
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| 1 |
EC50 = 342 nM
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CP0444710
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5-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]pyridine-2-carboxylic acid
Show/Hide
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C26H23Cl2N3O3
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1
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| 1 |
EC50 = 342 nM
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CP0502625
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propan-2-yl 1,1-dimethyl-3-[4-(3-pyrrolidin-1-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H39N3O4
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1
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| 1 |
EC50 = 362 nM
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CP0387462
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propan-2-yl 1,1-dimethyl-3-[3-[(4-methylpiperazin-1-yl)methyl]benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H38N4O3
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1
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| 1 |
EC50 = 368 nM
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CP0223209
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3-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-(2-hydroxyethoxy)cyclobutyl]benzoic acid
Show/Hide
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C32H28Cl3NO6
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1
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| 1 |
EC50 = 377 nM
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CP0093212
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4-(6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-ylcarbamoyl)benzoic acid
Show/Hide
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C27H20Cl2F3N3O5
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2
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| 1 |
EC50 = 385 nM
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| 2 |
EC50 = 474 nM
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CP0508408
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3-[[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-naphthalen-1-ylcarbamoyl]benzoic acid
Show/Hide
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C37H27Cl3N2O5
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1
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| 1 |
EC50 = 410 nM
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CP0502626
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propan-2-yl 1,1-dimethyl-3-[4-(3-piperidin-1-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C33H41N3O4
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1
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| 1 |
EC50 = 424 nM
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CP0510111
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propan-2-yl 3-[4-[2-(dimethylamino)ethoxy]benzoyl]-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C29H35N3O4
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1
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| 1 |
EC50 = 439 nM
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CP0177102
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5-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]pyridine-2-carboxylic acid
Show/Hide
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C25H24Cl2FN3O4
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1
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| 1 |
EC50 = 440 nM
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CP0522070
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propan-2-yl 8-fluoro-1,1-dimethyl-3-[4-(morpholin-4-ylmethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C30H34FN3O4
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1
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| 1 |
EC50 = 447 nM
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CP0363603
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6-[2-[5-cyclopropyl-3-(2,6-dichloro-4-fluorophenyl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]quinoline-2-carboxylic acid
Show/Hide
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C30H24Cl2FN3O3
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1
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| 1 |
EC50 = 522 nM
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CP0426926
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propan-2-yl 1,1-dimethyl-3-[3-(piperidin-1-ylmethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H37N3O3
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1
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| 1 |
EC50 = 534 nM
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CP0195438
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3-(2,6-dichlorophenyl)-5-isopropyl-4-((4-methylquinolin-2-yloxy)methyl)isoxazole
Show/Hide
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C23H20Cl2N2O2
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2
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| 1 |
EC50 = 536 nM
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| 2 |
EC50 = 878 nM
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CP0269599
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3-((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)carbamoyl)benzoic acid
Show/Hide
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C28H22Cl2F3N3O5
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2
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| 1 |
EC50 = 537 nM
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| 2 |
EC50 = 571 nM
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CP0578350
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ethyl 2-[3-[cyclohexanecarbonyl-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]-1,3-oxazole-4-carboxylate
Show/Hide
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C33H40N4O5
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1
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| 1 |
EC50 = 538 nM
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CP0197643
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5-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxyazetidin-1-yl]pyridine-3-carboxylic acid
Show/Hide
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C28H22Cl3N3O5
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1
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| 1 |
EC50 = 552 nM
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CP0502377
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propan-2-yl 1,1-dimethyl-3-[4-(2-morpholin-4-ylethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H37N3O4
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1
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| 1 |
EC50 = 602 nM
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CP0093221
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2-((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)methoxy)benzoic acid
Show/Hide
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C27H19Cl2F3N2O5
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2
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| 1 |
EC50 = 611 nM
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| 2 |
EC50 = 1710 nM
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CP0513952
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propan-2-yl 3-[3-[3-(dimethylamino)propoxy]benzoyl]-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C30H37N3O4
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1
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| 1 |
EC50 = 617 nM
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CP0400560
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propan-2-yl 2-cyano-6-(4-fluorobenzoyl)-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
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C22H24FN3O3
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1
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| 1 |
EC50 = 640 nM
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CP0507676
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propan-2-yl 1,1-dimethyl-3-[4-(2-pyrrolidin-1-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H37N3O4
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1
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| 1 |
EC50 = 698 nM
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CP0049016
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(4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethyl-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
Show/Hide
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C26H44O4
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1
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| 1 |
EC50 = 710 nM
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CP0177103
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2-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
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C27H23Cl2F2N3O4S
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1
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| 1 |
EC50 = 740 nM
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CP0552429
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6-[4-[[5-cyclopropyl-3-[3-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
Show/Hide
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C30H29F4N3O5
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1
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| 1 |
EC50 = 770 nM
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CP0492783
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propan-2-yl 1,1-dimethyl-3-[3-(3-morpholin-4-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H39N3O5
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1
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| 1 |
EC50 = 796 nM
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CP0433368
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3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)(2-phenylethyl)amido]benzoic acid
Show/Hide
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C35H29Cl3N2O5
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1
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| 1 |
EC50 = 840 nM
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CP0387465
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propan-2-yl 1,1-dimethyl-3-[3-(2-morpholin-4-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H37N3O5
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1
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| 1 |
EC50 = 855 nM
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CP0502611
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propan-2-yl 1,1-dimethyl-3-[3-(2-piperidin-1-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H39N3O4
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1
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| 1 |
EC50 = 894 nM
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CP0361689
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3-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1H-indazole-6-carboxylic acid
Show/Hide
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C27H25Cl2FN4O4
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1
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| 1 |
EC50 = 910 nM
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CP0550453
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ethyl 4-[3-[cyclohexanecarbonyl-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]amino]phenyl]-1,3-thiazole-2-carboxylate
Show/Hide
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C33H40N4O4S
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1
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| 1 |
EC50 = 919 nM
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CP0195441
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2-(4-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzamido)ethanesulfonic acid
Show/Hide
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C30H27Cl2F3N4O6S
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2
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| 1 |
EC50 = 925 nM
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| 2 |
EC50 = 1420 nM
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CP0288383
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3-(2,6-dichlorophenyl)-5-isopropyl-4-((4-methyl-5-nitropyridin-2-yloxy)methyl)isoxazole
Show/Hide
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C19H17Cl2N3O4
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2
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| 1 |
EC50 = 1000 nM
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| 2 |
EC50 = 1140 nM
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CP0514345
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propan-2-yl 1,1-dimethyl-3-[3-[3-(4-methylpiperazin-1-yl)propoxy]benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C33H42N4O4
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1
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| 1 |
EC50 = 1023 nM
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CP0492782
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propan-2-yl 1,1-dimethyl-3-[4-(2-piperidin-1-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H39N3O4
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1
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| 1 |
EC50 = 1066 nM
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CP0569332
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]-1,1-dioxothiane-4-carboxamide
Show/Hide
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C31H37N5O5S
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1
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| 1 |
EC50 = 1092 nM
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CP0389742
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3-[butyl-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]benzoyl]amino]benzoic acid
Show/Hide
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C31H29Cl3N2O5
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1
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| 1 |
EC50 = 1100 nM
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CP0502893
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propan-2-yl 1,1-dimethyl-3-[3-(3-piperidin-1-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C33H41N3O4
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1
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| 1 |
EC50 = 1121 nM
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CP0035664
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4-((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-methylpyridin-3-yl)(methyl)carbamoyl)benzoic acid
Show/Hide
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C28H25Cl2N3O5
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2
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| 1 |
EC50 = 1190 nM
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| 2 |
EC50 = 2030 nM
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CP0573236
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6-[4-[[5-cyclopropyl-3-[3-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-benzothiophene-3-carboxylic acid
Show/Hide
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C29H26F4N2O5S
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1
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| 1 |
EC50 = 1240 nM
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CP0405459
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3-[(E)-2-(4-{[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-2-chlorophenyl)ethenyl]benzoic acid
Show/Hide
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C29H24Cl3NO4
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1
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| 1 |
EC50 = 1300 nM
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CP0465554
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3-[(4-{[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-2-chlorobenzene)amido]benzoic acid
Show/Hide
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C28H23Cl3N2O5
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1
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| 1 |
EC50 = 1300 nM
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CP0473949
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propan-2-yl 6-(3-chlorobenzoyl)-2-cyano-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
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C22H24ClN3O3
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1
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| 1 |
EC50 = 1300 nM
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CP0510764
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propan-2-yl 2-cyano-6-(3-fluorobenzoyl)-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
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C22H24FN3O3
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1
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| 1 |
EC50 = 1300 nM
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CP0510112
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propan-2-yl 1,1-dimethyl-3-[3-(2-pyrrolidin-1-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C31H37N3O4
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1
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| 1 |
EC50 = 1317 nM
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CP0579314
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2-[3-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
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C27H22Cl2FN3O5S
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1
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| 1 |
EC50 = 1359 nM
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CP0223208
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2-[[4-[2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]cyclopropyl]benzoyl]amino]ethanesulfonic acid
Show/Hide
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C31H27Cl3N2O6S
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1
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| 1 |
EC50 = 1372 nM
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CP0387464
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propan-2-yl 3-[3-[2-(dimethylamino)ethoxy]benzoyl]-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C29H35N3O4
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1
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| 1 |
EC50 = 1386 nM
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CP0439111
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propan-2-yl 1,1-dimethyl-3-[3-(morpholin-4-ylmethyl)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C30H35N3O4
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1
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| 1 |
EC50 = 1579 nM
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CP0387466
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propan-2-yl 1,1-dimethyl-3-[3-(3-pyrrolidin-1-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H39N3O4
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1
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| 1 |
EC50 = 1603 nM
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CP0569150
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N-[[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1-bicyclo[2.2.2]octanyl]methyl]-N-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]-1-methylpiperidine-4-carboxamide
Show/Hide
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C32H40N6O3
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1
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| 1 |
EC50 = 1638 nM
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CP0400561
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propan-2-yl 2-cyano-6-(cyclohexanecarbonyl)-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
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C22H31N3O3
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1
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| 1 |
EC50 = 1900 nM
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CP0405449
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3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)(propyl)amido]benzoic acid
Show/Hide
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C30H27Cl3N2O5
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1
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| 1 |
EC50 = 2100 nM
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CP0374446
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3-[benzyl(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)amido]benzoic acid
Show/Hide
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C34H27Cl3N2O5
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1
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| 1 |
EC50 = 2500 nM
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CP0490914
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4-[benzyl-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]benzoyl]amino]benzoic acid
Show/Hide
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C34H27Cl3N2O5
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1
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| 1 |
EC50 = 2600 nM
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CP0520514
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propan-2-yl 2-cyano-4,4-dimethyl-6-[3-(trifluoromethyl)benzoyl]-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
Show/Hide
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C23H24F3N3O3
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1
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| 1 |
EC50 = 2700 nM
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CP0444795
|
2-[4-[[5-cyclopropyl-3-[3-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
Show/Hide
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C28H24F5N3O5S
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1
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| 1 |
EC50 = 2730 nM
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CP0514348
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propan-2-yl 1,1-dimethyl-3-[3-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Show/Hide
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C32H40N4O4
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1
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| 1 |
EC50 = 2870 nM
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CP0400276
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3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)amido]benzoic acid
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C27H21Cl3N2O5
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1
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| 1 |
EC50 = 3000 nM
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CP0400158
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3-[[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]benzoyl]-naphthalen-1-ylamino]benzoic acid
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C37H27Cl3N2O5
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1
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| 1 |
EC50 = 3000 nM
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CP0525696
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3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)(methyl)amido]benzoic acid
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C28H23Cl3N2O5
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1
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| 1 |
EC50 = 3100 nM
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CP0373755
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propan-2-yl 2-cyano-4,4-dimethyl-6-(oxane-4-carbonyl)-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
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C21H29N3O4
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1
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| 1 |
EC50 = 3300 nM
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CP0524029
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propan-2-yl 6-(4-chlorobenzoyl)-2-cyano-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
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C22H24ClN3O3
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1
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| 1 |
EC50 = 4100 nM
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CP0473884
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propan-2-yl 2-cyano-6-(4-cyanobenzoyl)-4,4-dimethyl-1,5,7,8-tetrahydropyrrolo[2,3-d]azepine-8-carboxylate
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C23H24N4O3
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1
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| 1 |
EC50 = 5700 nM
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CP0400042
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3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]-N-propylbenzamide
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C31H29Cl3N2O3
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1
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| 1 |
EC50 = 9000 nM
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CP0433367
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3-[benzyl-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]carbamoyl]benzoic acid
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C34H27Cl3N2O5
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1
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| 1 |
EC50 > 10000 nM
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CP0177107
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6-[4-[[5-cyclopropyl-3-[4-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
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C30H29F4N3O5
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1
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| 1 |
EC50 = 16770 nM
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CP0444708
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2-[3-[(E)-2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]ethenyl]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
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C29H24Cl2FN3O3S
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1
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| 1 |
EC50 > 20000 nM
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CP0002372
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(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
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C24H40O4
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1
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| 1 |
EC50 = 27000 nM
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CP0533065
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Isoxazole derivative, 11b
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C42H35Cl3N2O3
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1
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| 1 |
EC50 = 35100 nM
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CP0573407
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2-[4-[[5-cyclopropyl-3-[4-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
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C28H24F5N3O5S
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1
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| 1 |
EC50 = 44660 nM
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CP0115182
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DEOXYCHOLATE
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C24H40O4
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1
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| 1 |
EC50 = 50000 nM
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CP0253751
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3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4-phenylphenyl)-1,2-oxazol-4-yl]methoxy}benzene)amido]benzoic acid
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C36H23Cl3N2O5
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1
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| 1 |
IC50 = 3700 nM
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CP0253752
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3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(naphthalen-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)amido]benzoic acid
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C34H21Cl3N2O5
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1
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| 1 |
IC50 = 4000 nM
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CP0077405
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(Z)-Gugglesterone
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C21H28O2
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1
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| 1 |
IC50 = 12000 nM
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CP0373552
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3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-phenyl-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
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C31H20Cl3NO4
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1
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| 1 |
IC50 = 15800 nM
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CP0436777
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3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(naphthalen-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
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C35H22Cl3NO4
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1
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| 1 |
IC50 = 22200 nM
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CP0436741
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3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4-phenylphenyl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
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C37H24Cl3NO4
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1
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| 1 |
IC50 = 33900 nM
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