Brief Information of the Compound and Protein
Compound Name
2-[2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]-1,3-dioxa-8-azaspiro[4.5]decan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
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PubChem ID
CID: 138591733
Canonical SMILES
OC(=O)c1cc(F)c2nc(sc2c1)N1CCC2(COC(O2)c2c(onc2-c2c(Cl)cccc2Cl)C2CC2)CC1
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Compound Formula C27H22Cl2FN3O5S
Compound Structure
Protein Name
Bile acid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 227 nM
   TI
   LI
   LO
   TS