Brief Information of the Compound and Protein
Compound Name
2-[6-[(E)-2-[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]ethenyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
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PubChem ID
CID: 142582280
Canonical SMILES
OC(=O)c1cc(F)c2nc(sc2c1)N1CC2C(C1)C2\C=C\c1c(onc1-c1c(Cl)cccc1Cl)C1CC1
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Compound Formula C27H20Cl2FN3O3S
Compound Structure
Protein Name
Bile acid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 609 nM