Brief Information of the Compound and Protein
Compound Name
2-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1,3-benzothiazole-5-carboxylic acid
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Canonical SMILES
OC(=O)c1ccc2sc(nc2c1)N1CCC(F)(COCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)CC1
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Compound Formula C27H24Cl2FN3O4S
Compound Structure
Protein Name
Bile acid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 330 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 4290 nM