| Compound ID |
Compound Name |
Compound Formula |
|
CP0086292
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethylpiperidin-4-yl)oxypyridine-2-carboxamide
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|
C27H34N6O4
|
2
|
| 1 |
IC50 = 6.9 nM
|
|
|
| 2 |
Kd = 0.8 nM
|
|
|
|
CP0120915
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C31H42N6O4
|
2
|
| 1 |
IC50 = 10.5 nM
|
|
|
| 2 |
Kd = 1.57 nM
|
|
|
|
CP0538574
|
3-(5-methoxy-6-(4-methoxybenzyloxy)pyridin-3-yloxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
Show/Hide
|
C22H22N6O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0086291
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1,2,2,6,6-pentamethylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C30H40N6O4
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
Kd = 1 nM
|
|
|
|
CP0005166
|
BMS-354825
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|
C22H26ClN7O2S
|
1
|
| 1 |
IC50 = 18.3 nM
|
|
|
|
CP0460969
|
3-((5-methoxy-6-(4-methoxybenzyloxy)pyridin-3-yl)methoxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
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|
C23H24N6O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0340622
|
(S)-(4-(5-amino-6-(2,6-dichlorobenzylamino)pyrazin-2-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C27H30Cl2N6O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0460968
|
3-(3-methoxy-4-(4-methoxybenzyloxy)benzyloxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
Show/Hide
|
C24H25N5O4
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0244577
|
(S)-(4-(5-amino-6-(2,6-dichlorobenzyloxy)pyrazin-2-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone
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|
C27H29Cl2N5O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0321403
|
5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide
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|
C22H26N4O2
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0382796
|
3-((4-methoxy-5-(4-methoxybenzyloxy)pyridin-2-yl)methoxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
Show/Hide
|
C23H24N6O4
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0302228
|
4-cyano-N-(2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
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|
C17H18N4O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0336739
|
5-cyano-N-(5-((2,3-dihydroxypropoxy)methyl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C21H25N3O5
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0109216
|
4-nitro-N-(2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
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|
C16H18N4O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0513780
|
5-cyano-N-(5-(hydroxymethyl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
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|
C18H19N3O3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0370316
|
N-[2-[4-(2-hydroxyethyl)piperidin-1-yl]phenyl]-5-nitrofuran-2-carboxamide
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|
C18H21N3O5
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0086098
|
5-cyano-N-[5-(hydroxymethyl)-2-(4-methylpiperidin-1-yl)phenyl]furan-2-carboxamide
Show/Hide
|
C19H21N3O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0526494
|
N-[2-(4-methylpiperidin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
Show/Hide
|
C17H19N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0354096
|
5-cyano-N-(5-(methylsulfonamidomethyl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
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|
C19H22N4O4S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0369265
|
5-cyano-N-(5-formyl-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0244639
|
3-N-[(2,6-dichlorophenyl)methyl]-5-(1-methylpyrazol-4-yl)pyrazine-2,3-diamine
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|
C15H14Cl2N6
|
1
|
| 1 |
IC50 = 345 nM
|
|
|
|
CP0368685
|
5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C16H17N3O4
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0109217
|
N-[2-(4-hydroxypiperidin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
Show/Hide
|
C16H17N3O5
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0370313
|
5-cyano-N-(2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0177260
|
5-cyano-N-(5-cyano-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0370312
|
5-cyano-N-(5-methoxy-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C18H19N3O3
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0177258
|
5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 1010 nM
|
|
|
|
CP0109218
|
N-[2-(4-methylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
Show/Hide
|
C16H18N4O4
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0302229
|
N-[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]-5-nitrofuran-2-carboxamide
Show/Hide
|
C17H19N3O5
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0358260
|
3-(2,6-dichlorobenzyloxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
Show/Hide
|
C15H13Cl2N5O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0364325
|
3-(2-chlorobenzyloxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
Show/Hide
|
C15H14ClN5O
|
1
|
| 1 |
IC50 = 1990 nM
|
|
|
|
CP0541657
|
N-[2-(azepin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
Show/Hide
|
C17H13N3O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0109220
|
N-[2-(3-methylpiperidin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
Show/Hide
|
C17H19N3O4
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0370310
|
5-cyano-furan-2-carboxylic acid (5-guanidinomethyl-2-piperidin-1-yl-phenyl)-amide
Show/Hide
|
C19H22N6O2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0315539
|
5-cyano-N-(5-hydroxy-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0177261
|
N-[5-(aminomethyl)-2-piperidin-1-ylphenyl]-5-cyanofuran-2-carboxamide
Show/Hide
|
C18H20N4O2
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0275670
|
4-[[[2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C22H26N6O3S
|
1
|
| 1 |
IC50 = 5060 nM
|
|
|
|
CP0169053
|
4-[[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C17H17BrF3N7O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0496364
|
4-[[[2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C17H18F3N7O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0551444
|
N-[3-[[4-[(4-sulfamoylphenyl)methylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C22H25N7O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0340908
|
3-(2-cyanofuran-5-carboxamido)-4-(piperidin-1-yl)benzoic acid
Show/Hide
|
C18H17N3O4
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
|
CP0518142
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-piperidin-4-yloxypyridine-2-carboxamide
Show/Hide
|
C25H30N6O4
|
1
|
| 1 |
Kd = 0.6 nM
|
|
|
|
CP0523502
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[(1-ethylpiperidin-4-yl)methyl]pyridine-2-carboxamide
Show/Hide
|
C28H36N6O3
|
1
|
| 1 |
Kd = 1 nM
|
|
|
|
CP0481760
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-tert-butylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C29H38N6O4
|
1
|
| 1 |
Kd = 1.12 nM
|
|
|
|
CP0523443
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-propan-2-ylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C28H36N6O4
|
1
|
| 1 |
Kd = 1.2 nM
|
|
|
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CP0441092
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-cyclopropylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C28H34N6O4
|
1
|
| 1 |
Kd = 1.28 nM
|
|
|
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CP0499589
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-methylpyridine-2-carboxamide
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
Kd = 1.6 nM
|
|
|
|
CP0381932
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C29H38N6O4
|
1
|
| 1 |
Kd = 1.8 nM
|
|
|
|
CP0458957
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-piperidin-4-yloxypyridine-2-carboxamide
Show/Hide
|
C25H30N6O4
|
1
|
| 1 |
Kd = 1.8 nM
|
|
|
|
CP0458958
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-methylpyridine-2-carboxamide
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
Kd = 2 nM
|
|
|
|
CP0523444
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-(1-ethylpiperidin-4-yl)oxypyridine-2-carboxamide
Show/Hide
|
C27H34N6O4
|
1
|
| 1 |
Kd = 3 nM
|
|
|
|
CP0523442
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethylpiperidin-4-yl)pyridine-2-carboxamide
Show/Hide
|
C27H34N6O3
|
1
|
| 1 |
Kd = 3.1 nM
|
|
|
|
CP0441094
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxypyridine-2-carboxamide
Show/Hide
|
C27H31F3N6O4
|
1
|
| 1 |
Kd = 3.4 nM
|
|
|
|
CP0381929
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[(4-methylpiperazin-1-yl)methyl]pyridine-2-carboxamide
Show/Hide
|
C26H33N7O3
|
1
|
| 1 |
Kd = 4.9 nM
|
|
|
|
CP0127888
|
AB-460
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
Kd = 8.5 nM
|
|
|
|
CP0113988
|
CEP-32496
Show/Hide
|
C24H22F3N5O5
|
1
|
| 1 |
Kd = 9 nM
|
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|
