Brief Information of the Compound and Protein
Compound Name
5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
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PubChem ID
CID: 11395681
SID: 16490508
Canonical SMILES
CN1CCN(Cc2ccc(N3CCCCC3)c(NC(=O)c3ccc(o3)C#N)c2)CC1
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Compound Formula C23H29N5O2
Compound Structure
Protein Name
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P07333
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1010 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 80 nM