Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BMS-354825
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 PubChem ID
CID: 3062316
SID: 12015788
Canonical SMILES
Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
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Compound Formula C22H26ClN7O2S
Compound Structure
Protein Name
 Protein Info 
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P07333
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000121 FDC-P1
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 7.4 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.57 nM
2 IC50 = 5.012 nM
3 Kd = 0.58 nM