Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(4-(5-amino-6-(2,6-dichlorobenzyloxy)pyrazin-2-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone
    Show/Hide
 PubChem ID
CID: 46880843
Canonical SMILES
Nc1ncc(nc1OCc1c(Cl)cccc1Cl)-c1ccc(cc1)C(=O)N1CCC[C@H]1CN1CCCC1
    Show/Hide
Compound Formula C27H29Cl2N5O2
Compound Structure
Protein Name
 Protein Info 
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P07333
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS