General Information of the Compound
| Compound ID |
CP0458957
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| Compound Name |
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-piperidin-4-yloxypyridine-2-carboxamide
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| Structure |
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| Formula |
C25H30N6O4
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| Molecular Weight |
478.553
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| Canonical SMILES |
CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3cc(OC4CCNCC4)ccn3)cc2)no1
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| InChI |
InChI=1S/C25H30N6O4/c1-25(2,3)21-15-22(31-35-21)30-24(33)29-17-6-4-16(5-7-17)28-23(32)20-14-19(10-13-27-20)34-18-8-11-26-12-9-18/h4-7,10,13-15,18,26H,8-9,11-12H2,1-3H3,(H,28,32)(H2,29,30,31,33)
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| InChIKey |
PSABAQPTDYJLPZ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02032, Macrophage colony-stimulating factor 1 receptor
Protein ID: PT01008, Macrophage colony-stimulating factor 1 receptor
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3