Brief Information of the Compound and Protein
Compound Name
AB-460
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PubChem ID
CID: 11189588
SID: 16270620
Canonical SMILES
CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3cc4ccccc4cn3)cc2)no1
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Compound Formula C24H23N5O3
Compound Structure
Protein Name
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P07333
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Kd = 8.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 8.5 nM