General Information of the Compound
| Compound ID |
CP0381929
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| Compound Name |
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[(4-methylpiperazin-1-yl)methyl]pyridine-2-carboxamide
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| Structure |
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| Formula |
C26H33N7O3
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| Molecular Weight |
491.596
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| Canonical SMILES |
CN1CCN(Cc2ccc(nc2)C(=O)Nc2ccc(NC(=O)Nc3cc(on3)C(C)(C)C)cc2)CC1
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| InChI |
InChI=1S/C26H33N7O3/c1-26(2,3)22-15-23(31-36-22)30-25(35)29-20-8-6-19(7-9-20)28-24(34)21-10-5-18(16-27-21)17-33-13-11-32(4)12-14-33/h5-10,15-16H,11-14,17H2,1-4H3,(H,28,34)(H2,29,30,31,35)
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| InChIKey |
YBJQFWOWWBZCJS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02032, Macrophage colony-stimulating factor 1 receptor
Protein ID: PT01008, Macrophage colony-stimulating factor 1 receptor
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3