Brief Information of the Cell Line and Protein
Cell Line ID: CL000040 , THP-1
Synonyms
THP1
THP 1
THPI
THP-1(ATCC)
THP-1-O
O-THP-1
Tohoku Hospital Pediatrics-1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0006
Protein ID: PT03614 , NACHT, LRR and PYD domains-containing protein 3
Gene Name NLRP3
Organism Homo sapiens, Human
Protein Classification Unclassified protein
Uniprot ID Q96P20
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000040  Protein ID: PT03614
 
Compound ID Compound Name Compound Formula
CP0527211
1-[N-cyano-S-(3-fluoro-4-methylphenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H21FN4O2S
 2
1
IC50 = 5.3 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0416514
1-[N-cyano-S-(4-methylphenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H22N4O2S
 2
1
IC50 = 6.8 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0060767
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea
   Show/Hide
C20H24N2O5S
 2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0540778
1-[N-cyano-S-(3-cyanophenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H19N5O2S
 2
1
IC50 = 11.7 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0574940
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-(4-methylphenyl)sulfonylurea
   Show/Hide
C20H22N2O3S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0547568
1-(N-cyano-S-phenylsulfonimidoyl)-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C20H20N4O2S
 2
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0559008
1-(N-cyano-S-pyridin-2-ylsulfonimidoyl)-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C19H19N5O2S
 2
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0362703
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C18H19N3O3S2
 3
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
2
IC50 = 26 nM
   TI
   LI
   LO
   TS
3
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0554912
sodium;N-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-N'-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylcarbamimidate
   Show/Hide
C20H23N2NaO5S
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0554913
ethyl (2R)-2-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoylamino)-3-pyrimidin-2-ylpropanoate
   Show/Hide
C22H26N4O3
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0540749
1-[N-cyano-S-(4-cyanophenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H19N5O2S
 2
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0547567
1-(benzenesulfonyl)-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C19H20N2O3S
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0437547
1-(N-cyano-S-pyridin-3-ylsulfonimidoyl)-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C19H19N5O2S
 2
1
IC50 = 36.3 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0544788
1-[[7-(dimethylamino)-2,1,3-benzothiadiazol-4-yl]sulfonyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H23N5O3S2
 1
1
IC50 = 49 nM
   TI
   LI
   LO
   TS
CP0543672
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[[(6S)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-3-yl]sulfonyl]urea
   Show/Hide
C20H25N5O4S
 1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
CP0542770
N-(3-hydroxyphenyl)-2-(1H-indol-6-yl)acetamide
   Show/Hide
C16H14N2O2
 3
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
2
IC50 = 77 nM
   TI
   LI
   LO
   TS
3
IC50 = 98 nM
   TI
   LI
   LO
   TS
CP0570752
1-[[7-(dimethylamino)-2,1,3-benzoxadiazol-4-yl]sulfonyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H23N5O4S
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0576034
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(7-methylsulfanyl-2,1,3-benzoxadiazol-4-yl)sulfonyl]urea
   Show/Hide
C20H20N4O4S2
 1
1
IC50 = 61 nM
   TI
   LI
   LO
   TS
CP0568547
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-thiophen-2-ylethenyl]sulfonylurea
   Show/Hide
C19H20N2O3S2
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0571837
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-(4-methyl-1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C19H21N3O3S2
 1
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
CP0563777
1-[(E)-2-[4-(ethylsulfonylmethyl)-1,3-thiazol-2-yl]ethenyl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H25N3O5S3
 1
1
IC50 = 79 nM
   TI
   LI
   LO
   TS
CP0553221
1-[(E)-2-[4-(ethylsulfanylmethyl)-1,3-thiazol-2-yl]ethenyl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H25N3O3S3
 1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS
CP0575911
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-thiophen-3-ylethenyl]sulfonylurea
   Show/Hide
C19H20N2O3S2
 1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
CP0578938
1-[[7-(dimethylamino)-2,1,3-benzoselenadiazol-4-yl]sulfonyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H23N5O3SSe
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0568289
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(7-morpholin-4-yl-2,1,3-benzoxadiazol-4-yl)sulfonyl]urea
   Show/Hide
C23H25N5O5S
 1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CP0437548
1-(N-cyano-S-pyridin-4-ylsulfonimidoyl)-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C19H19N5O2S
 2
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0537818
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-(1,3-thiazol-5-yl)ethenyl]sulfonylurea
   Show/Hide
C18H19N3O3S2
 1
1
IC50 = 126 nM
   TI
   LI
   LO
   TS
CP0565563
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-[4-(2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]ethenyl]sulfonylurea
   Show/Hide
C21H25N3O4S2
 1
1
IC50 = 142 nM
   TI
   LI
   LO
   TS
CP0573002
1-[(4-chloro-2,1,3-benzoxadiazol-7-yl)sulfonyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C19H17ClN4O4S
 1
1
IC50 = 146 nM
   TI
   LI
   LO
   TS
CP0537817
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-pyridin-4-ylethenyl]sulfonylurea
   Show/Hide
C20H21N3O3S
 1
1
IC50 = 164 nM
   TI
   LI
   LO
   TS
CP0580048
N-(3-hydroxyphenyl)-2-(4-propan-2-ylphenyl)acetamide
   Show/Hide
C17H19NO2
 1
1
IC50 = 176.8 nM
   TI
   LI
   LO
   TS
CP0465600
ethyl (2R)-2-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoylamino)-3-pyrazin-2-ylpropanoate
   Show/Hide
C22H26N4O3
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0571751
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-[4-(2-hydroxypropan-2-yl)furan-2-yl]ethenyl]sulfonylurea
   Show/Hide
C22H26N2O5S
 1
1
IC50 = 208 nM
   TI
   LI
   LO
   TS
CP0579058
N-(3-hydroxyphenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H15NO3
 1
1
IC50 = 239.2 nM
   TI
   LI
   LO
   TS
CP0571752
1-[(E)-2-[4-(ethylsulfinylmethyl)-1,3-thiazol-2-yl]ethenyl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H25N3O4S3
 1
1
IC50 = 243 nM
   TI
   LI
   LO
   TS
CP0577117
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[[7-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-2,1,3-benzoxadiazol-4-yl]sulfonyl]urea
   Show/Hide
C25H27N5O5S
 1
1
IC50 = 243 nM
   TI
   LI
   LO
   TS
CP0570344
1-[[7-[(3,3-difluorocyclobutyl)amino]-2,1,3-benzoxadiazol-4-yl]sulfonyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C23H23F2N5O4S
 1
1
IC50 = 247 nM
   TI
   LI
   LO
   TS
CP0568548
1-(8-methyl-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C19H21N3O3S2
 1
1
IC50 = 294 nM
   TI
   LI
   LO
   TS
CP0551549
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethenyl]sulfonylurea
   Show/Hide
C19H21N3O4S2
 1
1
IC50 = 306 nM
   TI
   LI
   LO
   TS
CP0553222
2-[(E)-2-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoylsulfamoyl)ethenyl]-N,N-dimethyl-1,3-thiazole-4-carboxamide
   Show/Hide
C21H24N4O4S2
 1
1
IC50 = 344 nM
   TI
   LI
   LO
   TS
CP0553220
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-(1,3-thiazol-4-yl)ethenyl]sulfonylurea
   Show/Hide
C18H19N3O3S2
 1
1
IC50 = 369 nM
   TI
   LI
   LO
   TS
CP0579774
2-[4-(difluoromethoxy)phenyl]-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C15H13F2NO3
 1
1
IC50 = 380.3 nM
   TI
   LI
   LO
   TS
CP0579043
2-(4-ethoxyphenyl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C16H17NO3
 1
1
IC50 = 387.3 nM
   TI
   LI
   LO
   TS
CP0576033
1-[[7-[[(1R,2R)-2-(dimethylamino)cyclohexyl]-methylamino]-2,1,3-benzoxadiazol-4-yl]sulfonyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C28H36N6O4S
 1
1
IC50 = 636 nM
   TI
   LI
   LO
   TS
CP0578007
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[[7-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2,1,3-benzoxadiazol-4-yl]sulfonyl]urea
   Show/Hide
C25H27N5O5S
 1
1
IC50 = 641 nM
   TI
   LI
   LO
   TS
CP0577141
2-(4-bromophenyl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C14H12BrNO2
 1
1
IC50 = 645.3 nM
   TI
   LI
   LO
   TS
CP0578937
tert-butyl N-[1-[4-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoylsulfamoyl)-2,1,3-benzoxadiazol-7-yl]azetidin-3-yl]carbamate
   Show/Hide
C27H32N6O6S
 1
1
IC50 = 947 nM
   TI
   LI
   LO
   TS
CP0513615
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-pyridin-2-ylethenyl]sulfonylurea
   Show/Hide
C20H21N3O3S
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0575912
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-(5-methyl-1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C19H21N3O3S2
 1
1
IC50 = 1061 nM
   TI
   LI
   LO
   TS
CP0544211
N-(3-hydroxyphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide
   Show/Hide
C15H12F3NO2
 1
1
IC50 = 1083 nM
   TI
   LI
   LO
   TS
CP0125619
(NE)-N-[1-(6-methoxy-1,3-benzoxazol-2-yl)-2-(4-methoxyphenyl)ethylidene]hydroxylamine
   Show/Hide
C17H16N2O4
 1
1
IC50 = 1220 nM
   TI
   LI
   LO
   TS
CP0040451
(E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone
   Show/Hide
C15H12O4
 1
1
IC50 = 1540 nM
   TI
   LI
   LO
   TS
CP0579055
N-(3-hydroxyphenyl)-2-naphthalen-2-ylacetamide
   Show/Hide
C18H15NO2
 1
1
IC50 = 1621 nM
   TI
   LI
   LO
   TS
CP0580049
N-(3-hydroxyphenyl)-2-(4-propylphenyl)acetamide
   Show/Hide
C17H19NO2
 1
1
IC50 = 2208 nM
   TI
   LI
   LO
   TS
CP0579775
N-(3-hydroxyphenyl)-2-[4-(trifluoromethoxy)phenyl]acetamide
   Show/Hide
C15H12F3NO3
 1
1
IC50 = 2318 nM
   TI
   LI
   LO
   TS
CP0567939
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[[7-[4-(2-hydroxyethyl)piperazin-1-yl]-2,1,3-benzoxadiazol-4-yl]sulfonyl]urea
   Show/Hide
C25H30N6O5S
 1
1
IC50 = 2380 nM
   TI
   LI
   LO
   TS
CP0568048
N-(3-hydroxyphenyl)-2-(4-methylphenyl)acetamide
   Show/Hide
C15H15NO2
 1
1
IC50 = 2821 nM
   TI
   LI
   LO
   TS
CP0542774
[3-[[2-(4-methoxyphenyl)acetyl]amino]phenyl]boronic acid
   Show/Hide
C15H16BNO4
 1
1
IC50 = 3136 nM
   TI
   LI
   LO
   TS
CP0543130
2-(4-acetamidophenyl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C16H16N2O3
 1
1
IC50 = 3625 nM
   TI
   LI
   LO
   TS
CP0544226
2-(4-chlorophenyl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C14H12ClNO2
 1
1
IC50 = 3986 nM
   TI
   LI
   LO
   TS
CP0570066
N-[(3-hydroxyphenyl)methyl]-2-(1H-indol-6-yl)acetamide
   Show/Hide
C17H16N2O2
 1
1
IC50 = 4146 nM
   TI
   LI
   LO
   TS
CP0579042
N-(3-hydroxyphenyl)-2-(1-oxoisoquinolin-2-yl)acetamide
   Show/Hide
C17H14N2O3
 1
1
IC50 = 5035 nM
   TI
   LI
   LO
   TS
CP0323991
(NE)-N-[1-(6-chloro-1,3-benzoxazol-2-yl)-2-(4-methoxyphenyl)ethylidene]hydroxylamine
   Show/Hide
C16H13ClN2O3
 1
1
IC50 = 5720 nM
   TI
   LI
   LO
   TS
CP0578679
N-(3-hydroxyphenyl)-2-(1H-indol-6-yl)-N-methylacetamide
   Show/Hide
C17H16N2O2
 1
1
IC50 = 7096 nM
   TI
   LI
   LO
   TS
CP0575489
1-[5-(dimethylamino)naphthalen-1-yl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C25H27N3O3S
 1
1
IC50 = 9180 nM
   TI
   LI
   LO
   TS
CP0579627
2-(4-tert-butylphenyl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C18H21NO2
 1
1
IC50 = 12420 nM
   TI
   LI
   LO
   TS
CP0579373
N-(3-hydroxyphenyl)-2-(1H-indol-2-yl)acetamide
   Show/Hide
C16H14N2O2
 1
1
IC50 = 13220 nM
   TI
   LI
   LO
   TS
CP0529325
(NE)-N-[1-(6-methyl-1,3-benzoxazol-2-yl)-2-phenylethylidene]hydroxylamine
   Show/Hide
C16H14N2O2
 1
1
IC50 = 15880 nM
   TI
   LI
   LO
   TS
CP0481849
(NE)-N-[1-(6-chloro-1,3-benzoxazol-2-yl)-2-phenylethylidene]hydroxylamine
   Show/Hide
C15H11ClN2O2
 1
1
IC50 = 21950 nM
   TI
   LI
   LO
   TS
CP0416497
[(E)-1-(1,3-benzoxazol-2-yl)ethylideneamino] 2-methoxybenzoate
   Show/Hide
C17H14N2O4
 1
1
IC50 = 39470 nM
   TI
   LI
   LO
   TS
CP0542769
N-[3-(hydroxymethyl)phenyl]-2-(4-methoxyphenyl)acetamide
   Show/Hide
C16H17NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0543129
2-(1,3-benzodioxol-5-yl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C15H13NO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0544227
N-(3-hydroxyphenyl)-2-(4-pentylphenyl)acetamide
   Show/Hide
C19H23NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0544228
methyl 3-[[2-(4-methoxyphenyl)acetyl]amino]benzoate
   Show/Hide
C17H17NO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0544229
3-[[2-(4-methoxyphenyl)acetyl]amino]benzoic acid
   Show/Hide
C16H15NO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0544230
2-(4-methoxyphenyl)-N-(3-sulfamoylphenyl)acetamide
   Show/Hide
C15H16N2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0544231
N-(3-hydroxyphenyl)-2-indol-1-ylacetamide
   Show/Hide
C16H14N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0549791
N-(1-hydroxy-3H-2,1-benzoxaborol-6-yl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C16H16BNO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0551222
N-(3-fluorophenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H14FNO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0551223
3-hydroxy-N-(1H-indol-6-ylmethyl)benzamide
   Show/Hide
C16H14N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0567983
N-(3-hydroxyphenyl)-2-(4-nitrophenyl)acetamide
   Show/Hide
C14H12N2O4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0568050
N-(1,3-dihydro-2-benzofuran-5-yl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C17H17NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569027
N-(3-hydroxyphenyl)-2-(4-phenylphenyl)acetamide
   Show/Hide
C20H17NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569028
N-(3-hydroxyphenyl)-2-(4-phenylmethoxyphenyl)acetamide
   Show/Hide
C21H19NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569029
N-(1,3-benzoxazol-6-yl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C16H14N2O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569030
N-[3-(difluoromethoxy)phenyl]-2-(4-methoxyphenyl)acetamide
   Show/Hide
C16H15F2NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569031
N-(2-hydroxyphenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H15NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569271
2-(4-methoxyphenyl)-N-(3-oxo-1,2-dihydroisoindol-5-yl)acetamide
   Show/Hide
C17H16N2O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569667
2-(4-methoxyphenyl)-N-(3-oxo-1,2-dihydroinden-5-yl)acetamide
   Show/Hide
C18H17NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569668
N-(3-chlorophenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H14ClNO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0570065
AS-114
   Show/Hide
C14H13NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0571156
N-(3-bromophenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H14BrNO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0572908
N-(3-hydroxyphenyl)-2-(1H-indol-4-yl)acetamide
   Show/Hide
C16H14N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0574411
N-(3-methoxyphenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C16H17NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0574412
N-(3-hydroxyphenyl)-2-(1H-indol-3-yl)acetamide
   Show/Hide
C16H14N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0576869
N-[3-(2-hydroxypropan-2-yl)phenyl]-2-(4-methoxyphenyl)acetamide
   Show/Hide
C18H21NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0576870
N-(4-hydroxyphenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H15NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0577131
N-(3-hydroxyphenyl)-2-(3-methoxyphenyl)acetamide
   Show/Hide
C15H15NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0577143
2-(4-methoxyphenyl)-N-(1-oxo-2,3-dihydroisoindol-5-yl)acetamide
   Show/Hide
C17H16N2O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0578675
N-(3-hydroxyphenyl)-2-naphthalen-1-ylacetamide
   Show/Hide
C18H15NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0578676
N-(3-hydroxyphenyl)-2-[4-(methanesulfonamido)phenyl]acetamide
   Show/Hide
C15H16N2O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0578677
2-(4-methoxyphenyl)-N-(3-nitrophenyl)acetamide
   Show/Hide
C15H14N2O4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0578678
2-(4-methoxyphenyl)-N-(3-methylphenyl)acetamide
   Show/Hide
C16H17NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579044
N-(3-hydroxyphenyl)-2-(4-hydroxyphenyl)acetamide
   Show/Hide
C14H13NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579045
2-(4-methoxyphenyl)-N-(3-oxo-1H-2-benzofuran-5-yl)acetamide
   Show/Hide
C17H15NO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579056
N-(3-aminophenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C15H16N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579057
2-(4-methoxyphenyl)-N-(1-oxo-3H-2-benzofuran-5-yl)acetamide
   Show/Hide
C17H15NO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579369
N-(3-hydroxyphenyl)-2-(2-methoxyphenyl)acetamide
   Show/Hide
C15H15NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579370
N-(2,2-difluoro-1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C16H13F2NO4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579371
N-(3-acetylphenyl)-2-(4-methoxyphenyl)acetamide
   Show/Hide
C17H17NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579372
2-(4-methoxyphenyl)-N-[3-(trifluoromethoxy)phenyl]acetamide
   Show/Hide
C16H14F3NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579626
2-(4-methoxyphenyl)-N-phenylacetamide
   Show/Hide
C15H15NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579772
N-(3-hydroxyphenyl)-2-quinolin-6-ylacetamide
   Show/Hide
C17H14N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579773
N-(3-hydroxyphenyl)-2-(4-methylsulfonylphenyl)acetamide
   Show/Hide
C15H15NO4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579892
2-(4-methoxyphenyl)-N-[3-(trifluoromethyl)phenyl]acetamide
   Show/Hide
C16H14F3NO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0580008
2-(2,3-dihydro-1-benzofuran-5-yl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C16H15NO3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0580011
N-(3-hydroxyphenyl)-1H-indole-6-carboxamide
   Show/Hide
C15H12N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0580047
2-(4-fluorophenyl)-N-(3-hydroxyphenyl)acetamide
   Show/Hide
C14H12FNO2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0416515
N-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylsulfamoyl)-4-methylbenzenesulfonamide
   Show/Hide
C19H22N2O4S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0416516
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-(2,2,2-trifluoro-1-phenylethyl)urea
   Show/Hide
C21H21F3N2O
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0437544
N-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyl)-phenylphosphonamidic acid
   Show/Hide
C19H21N2O3P
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0437545
2-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-N-(4-methylphenyl)sulfonyl-2-oxoacetamide
   Show/Hide
C21H21NO4S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0437546
1-[cyano(phenyl)methyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H21N3O
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0533437
N-[2-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylamino)-3,4-dioxocyclobuten-1-yl]-4-methylbenzenesulfonamide
   Show/Hide
C23H22N2O4S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0533438
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[S-(4-methylphenyl)-N-(2,2,2-trifluoroethyl)sulfonimidoyl]urea
   Show/Hide
C22H24F3N3O2S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0533439
N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoylamino)-(4-methylphenyl)-oxo-lambda6-sulfanylidene]acetamide
   Show/Hide
C22H25N3O3S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0540747
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[N-methyl-S-(4-methylphenyl)sulfonimidoyl]urea
   Show/Hide
C21H25N3O2S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0540748
1-[N-carbamoyl-S-(4-methylphenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C21H24N4O3S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0540776
2-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-2-hydroxy-N-(4-methylphenyl)sulfonylacetamide
   Show/Hide
C21H23NO4S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0547565
N-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-N'-(4-methylphenyl)sulfonyloxamide
   Show/Hide
C21H22N2O4S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0547566
2-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-N-(4-methylphenyl)sulfonylacetamide
   Show/Hide
C21H23NO3S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0547569
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[N-methoxy-S-(4-methylphenyl)sulfonimidoyl]urea
   Show/Hide
C21H25N3O3S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0547570
ethyl N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoylamino)-(4-methylphenyl)-oxo-lambda6-sulfanylidene]carbamate
   Show/Hide
C23H27N3O4S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0548589
1-cyano-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-2-(4-methylphenyl)sulfonylguanidine
   Show/Hide
C21H22N4O2S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0559007
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-(3-phenyloxetan-3-yl)urea
   Show/Hide
C22H24N2O2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0559736
1-[N-(4-fluorophenyl)-S-(4-methylphenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C26H26FN3O2S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0878648
N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4-methyl-N'-(1H-pyrazol-5-yl)benzenesulfonimidamide
   Show/Hide
C23H25N5O2S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0513616
1-(2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-4-yl)-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C16H15N3O5S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0537815
1-(2,6-dimethoxyphenyl)-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C14H15N3O5S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0537816
1-(2,3,5,6-tetramethylphenyl)-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C16H19N3O3S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0538537
1-[2-fluoro-6-(trifluoromethyl)phenyl]-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C13H9F4N3O3S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0538538
1-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
   Show/Hide
C22H21N3O3S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0543437
1-[2,6-di(propan-2-yl)phenyl]-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C18H23N3O3S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0553219
1-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonyl-3-[2-(trifluoromethyl)phenyl]urea
   Show/Hide
C13H10F3N3O3S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0554628
1-[2,5-bis(trifluoromethyl)phenyl]-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
   Show/Hide
C14H9F6N3O3S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS