Brief Information of the Compound and Protein
Compound Name
1-[(E)-2-[4-(ethylsulfanylmethyl)-1,3-thiazol-2-yl]ethenyl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
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PubChem ID
CID: 137525453
Canonical SMILES
CCSCc1csc(\C=C\S(=O)(=O)NC(=O)Nc2c3CCCc3cc3CCCc23)n1
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Compound Formula C21H25N3O3S3
Compound Structure
Protein Name
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q96P20
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 93 nM
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