Brief Information of the Compound and Protein
Compound Name
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(E)-2-[4-(2-hydroxypropan-2-yl)furan-2-yl]ethenyl]sulfonylurea
    Show/Hide
PubChem ID
CID: 137528139
Canonical SMILES
CC(C)(O)c1coc(\C=C\S(=O)(=O)NC(=O)Nc2c3CCCc3cc3CCCc23)c1
    Show/Hide
Compound Formula C22H26N2O5S
Compound Structure
Protein Name
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q96P20
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 208 nM
   TI
   LI
   LO
   TS