Brief Information of the Compound and Protein
Compound Name
1-[2,5-bis(trifluoromethyl)phenyl]-3-[(E)-2-(1,3-thiazol-2-yl)ethenyl]sulfonylurea
    Show/Hide
PubChem ID
CID: 142536224
Canonical SMILES
FC(F)(F)c1ccc(c(NC(=O)NS(=O)(=O)\C=C\c2nccs2)c1)C(F)(F)F
    Show/Hide
Compound Formula C14H9F6N3O3S2
Compound Structure
Protein Name
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q96P20
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS