Brief Information of the Compound and Protein
Compound Name
1-[N-cyano-S-(4-cyanophenyl)sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
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PubChem ID
CID: 142490267
Canonical SMILES
O=C(Nc1c2CCCc2cc2CCCc12)NS(=O)(=NC#N)c1ccc(cc1)C#N
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Compound Formula C21H19N5O2S
Compound Structure
Protein Name
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q96P20
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS