| Compound ID |
Compound Name |
Compound Formula |
|
CP0126041
|
2-(4-acetylpiperazin-1-yl)-4-[isoquinolin-3-ylmethyl(methyl)amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C26H31N7O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0007475
|
2-(4-acetylpiperazin-1-yl)-6-propan-2-yl-4-(quinolin-3-ylmethylamino)-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H29N7O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0110947
|
2-(4-acetylpiperazin-1-yl)-4-(isoquinolin-3-ylmethylamino)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H29N7O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0315753
|
2-(4-acetylpiperazin-1-yl)-4-[[(1R)-1-(4-ethoxy-3-fluorophenyl)ethyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H33FN6O3
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0011363
|
2-(4-acetylpiperazin-1-yl)-4-[[1-(4-chlorophenyl)-2-methylpropan-2-yl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H33ClN6O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0315751
|
2-(4-acetylpiperazin-1-yl)-6-propan-2-yl-4-[[(1R)-1-[4-(trifluoromethoxy)phenyl]ethyl]amino]-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H29F3N6O3
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0548327
|
2-(4-acetylpiperazin-1-yl)-4-[[2-methoxy-4-(trifluoromethoxy)phenyl]methylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H29F3N6O4
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0525961
|
2-(4-acetylpiperazin-1-yl)-4-[[(1R)-1-(4-ethoxyphenyl)ethyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H34N6O3
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0315752
|
2-(4-acetylpiperazin-1-yl)-4-[[(1S)-1-(4-ethoxyphenyl)-2,2,2-trifluoroethyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H31F3N6O3
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0416718
|
2-(4-acetylpiperazin-1-yl)-4-[[(1R)-1-(4-ethoxyphenyl)propyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C26H36N6O3
|
1
|
| 1 |
IC50 = 212 nM
|
|
|
|
CP0524987
|
4-(benzhydrylamino)-2-(2-methoxyethylamino)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H29N5O2
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0513883
|
2-(4-acetylpiperazin-1-yl)-4-[[1-(4-chlorophenyl)cyclobutyl]methylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C26H33ClN6O2
|
1
|
| 1 |
IC50 = 262 nM
|
|
|
|
CP0380975
|
2-(4-acetylpiperazin-1-yl)-4-(benzhydrylamino)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C28H32N6O2
|
1
|
| 1 |
IC50 = 268 nM
|
|
|
|
CP0339972
|
2-(4-acetylpiperazin-1-yl)-6-propan-2-yl-4-[[4-(trifluoromethoxy)phenyl]methylamino]-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C23H27F3N6O3
|
1
|
| 1 |
IC50 = 324 nM
|
|
|
|
CP0524986
|
N-[1-[4-(benzhydrylamino)-7-oxo-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-2-yl]pyrrolidin-3-yl]acetamide
Show/Hide
|
C28H32N6O2
|
1
|
| 1 |
IC50 = 327 nM
|
|
|
|
CP0549411
|
4-(benzhydrylamino)-2-(4-methylsulfonylpiperazin-1-yl)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C27H32N6O3S
|
1
|
| 1 |
IC50 = 398 nM
|
|
|
|
CP0488455
|
2-[4-[4-(benzhydrylamino)-7-oxo-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-2-yl]piperazin-1-yl]-N,N-dimethylacetamide
Show/Hide
|
C30H37N7O2
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0415757
|
2-(4-acetylpiperazin-1-yl)-4-[2-(4-chlorophenyl)propylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H31ClN6O2
|
1
|
| 1 |
IC50 = 441 nM
|
|
|
|
CP0525962
|
2-(4-acetylpiperazin-1-yl)-4-[[(1R)-1-(6-ethoxy-5-fluoropyridin-3-yl)ethyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H32FN7O3
|
1
|
| 1 |
IC50 = 521 nM
|
|
|
|
CP0432177
|
2-(4-acetylpiperazin-1-yl)-4-[[(1R)-1-(4-methylphenyl)ethyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H32N6O2
|
1
|
| 1 |
IC50 = 613 nM
|
|
|
|
CP0489265
|
4-(benzhydrylamino)-2-piperazin-1-yl-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 = 618 nM
|
|
|
|
CP0416717
|
2-(4-acetylpiperazin-1-yl)-6-propan-2-yl-4-[[4-(trifluoromethyl)phenyl]methylamino]-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C23H27F3N6O2
|
1
|
| 1 |
IC50 = 1271 nM
|
|
|
|
CP0415756
|
2-(4-acetylpiperazin-1-yl)-4-[2-(4-methylphenyl)ethylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H32N6O2
|
1
|
| 1 |
IC50 = 1311 nM
|
|
|
|
CP0524985
|
4-(benzhydrylamino)-2-morpholin-4-yl-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
IC50 = 1360 nM
|
|
|
|
CP0417232
|
2-(4-acetylpiperazin-1-yl)-4-[2-(4-chlorophenyl)ethylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C23H29ClN6O2
|
1
|
| 1 |
IC50 = 1665 nM
|
|
|
|
CP0475821
|
4-(benzhydrylamino)-2-(4-methylpiperazin-1-yl)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C27H32N6O
|
1
|
| 1 |
IC50 = 1947 nM
|
|
|
|
CP0517547
|
2-(4-acetylpiperazin-1-yl)-4-[[2-(4-chlorophenyl)-2-methylpropyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C25H33ClN6O2
|
1
|
| 1 |
IC50 = 2057 nM
|
|
|
|
CP0110778
|
2-(4-acetylpiperazin-1-yl)-4-[[(1R)-1-(4-methoxyphenyl)ethyl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C24H32N6O3
|
1
|
| 1 |
IC50 = 2523 nM
|
|
|
|
CP0110777
|
2-(4-acetylpiperazin-1-yl)-4-[(4-chlorophenyl)methylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C22H27ClN6O2
|
1
|
| 1 |
IC50 = 4214 nM
|
|
|
|
CP0433242
|
4-(benzhydrylamino)-2-[4-[2-(dimethylamino)acetyl]piperazin-1-yl]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C30H37N7O2
|
1
|
| 1 |
IC50 = 5689 nM
|
|
|
|
CP0549788
|
2-(4-acetylpiperazin-1-yl)-4-(2-phenylethylamino)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 13950 nM
|
|
|
|
CP0489266
|
2-(4-acetylpiperazin-1-yl)-4-(benzylamino)-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
