Brief Information of the Compound and Protein
Compound Name
2-(4-acetylpiperazin-1-yl)-4-[[2-methoxy-4-(trifluoromethoxy)phenyl]methylamino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
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PubChem ID
CID: 57431849
Canonical SMILES
COc1cc(OC(F)(F)F)ccc1CNc1nc(nc2C(=O)N(Cc12)C(C)C)N1CCN(CC1)C(C)=O
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Compound Formula C24H29F3N6O4
Compound Structure
Protein Name
P2X purinoceptor 3
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
P56373
Gene Name
P2RX3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000761 RLE Rattus norvegicus (Rat)  1
1
IC50 = 67 nM
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