Brief Information of the Cell Line and Protein
Cell Line ID: CL000274 , SK-HEP-1
 Cell Line Info 
Synonyms
SK-Hep-1
SK HEP-1
SK HEP 01
SK-Hep1
Sk-Hep1
SK Hep1
SKHEP-1
SKHEP1
SKHep1
SK_HEP1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0525
Protein ID: PT02791 , Hypoxia-inducible factor 1-alpha
 Protein Info 
Gene Name HIF1A
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q16665
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000274
 Cell Line Info 
 Protein ID: PT02791
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0393031
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinamide
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C24H27N3O3
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442349
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-isonicotinamide
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C30H35N5O3
  1
1
IC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454169
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid methyl ester
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C25H28N2O4
  1
1
IC50 = 1030 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440841
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-nicotinamide
   Show/Hide
C30H35N5O3
  1
1
IC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0490586
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid
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C24H26N2O4
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399590
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-chloro-phenyl)-isonicotinamide
   Show/Hide
C30H30ClN3O3
  1
1
IC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0434361
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-isonicotinamide
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C31H34N4O3
  1
1
IC50 = 3400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454275
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-nicotinamide
   Show/Hide
C29H31N3O4
  1
1
IC50 = 4100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0449106
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinamide
   Show/Hide
C24H27N3O3
  1
1
IC50 = 11900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016093
 Compound Info 
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
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C19H16N2O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454170
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid
   Show/Hide
C24H26N2O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0454171
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid methyl ester
   Show/Hide
C25H28N2O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0457924
 Compound Info 
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-nicotinamide
   Show/Hide
C31H34N4O3
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0464172
 Compound Info 
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-isonicotinamide
   Show/Hide
C29H31N3O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS