| Compound ID |
Compound Name |
Compound Formula |
|
CP0859661
|
6-amino-2-[(1R)-1-methylbutoxy]-9-(4-piperidylmethyl)-7H-purin-8-one Hydrochloride
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|
C16H27ClN6O2
|
1
|
| 1 |
Activity = 0.4988 nM
|
|
|
|
CP0229826
|
6-amino-9-benzyl-2-(2-methoxyethoxy)-7H-purin-8(9H)-one
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|
C15H17N5O3
|
1
|
| 1 |
Activity = 5.27384 nM
|
|
|
|
CP0402138
|
6-amino-2-butoxy-9-[[1-(2-hydroxyethyl)piperidin-4-yl]methyl]-7H-purin-8-one;hydrochloride
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|
C17H29ClN6O3
|
1
|
| 1 |
Activity = 6.829463 nM
|
|
|
|
CP0859647
|
4-(5-(6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)pentyl)piperidinium chloride
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|
C19H33ClN6O2
|
1
|
| 1 |
Activity = 6.959343 nM
|
|
|
|
CP0859648
|
6-amino-2-[(1S)-1-methylbutoxy]-9-[5-(4-piperidyl)pentyl]-7H-purin-8-one Hydrochloride
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|
C20H35ClN6O2
|
1
|
| 1 |
Activity = 7.061055 nM
|
|
|
|
CP0859646
|
4-((6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)methyl)piperidinium chloride
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|
C15H25ClN6O2
|
1
|
| 1 |
Activity = 8.01715 nM
|
|
|
|
CP0437656
|
6-amino-9-[[1-(2-aminoethyl)piperidin-4-yl]methyl]-2-butoxy-7H-purin-8-one;hydrochloride
Show/Hide
|
C17H30ClN7O2
|
1
|
| 1 |
Activity = 15.335184 nM
|
|
|
|
CP0859644
|
6-amino-9-[[1-(2-hydroxyethyl)-4-piperidyl]methyl]-2-[(1S)-1-methylbutoxy]-7H-purin-8-one Hydrochloride
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|
C18H31ClN6O3
|
1
|
| 1 |
Activity = 24.719237 nM
|
|
|
|
CP0859645
|
6-amino-2-[(1S)-1-methylbutoxy]-9-(4-piperidylmethyl)-7H-purin-8-one Hydrochloride
Show/Hide
|
C16H27ClN6O2
|
1
|
| 1 |
Activity = 33.584082 nM
|
|
|
|
CP0870709
|
6-amino-9-[[1-(2-aminoethyl)-4-piperidyl]methyl]-2-[(1S)-1-methylbutoxy]-7H-purin-8-one Hydrochloride
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|
C18H32ClN7O2
|
1
|
| 1 |
Activity = 46.640899 nM
|
|
|
|
CP0233638
|
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
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|
C17H22N4O2
|
1
|
| 1 |
Activity = 62.820064 nM
|
|
|
|
CP0966188
|
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-N-((3S,4S)-3-fluoropiperidin-4-yl)-1H-indazol-3-amine
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|
C22H26FN5
|
1
|
| 1 |
IC50 = 0.05 nM
|
|
|
|
CP0528720
|
5-cyclopropyl-6-(3-fluoro-2-methylpyridin-4-yl)-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
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|
C22H26FN5
|
1
|
| 1 |
IC50 = 0.08 nM
|
|
|
|
CP0941521
|
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-N-((3R,4R)-3-fluoropiperidin-4-yl)-1H-indazol-3-amine
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|
C22H26FN5
|
1
|
| 1 |
IC50 = 0.08 nM
|
|
|
|
CP0964164
|
5-cyclopropyl-6-(3-fluoro-2-methylpyridin-4-yl)-N-((3S,4S)-3-fluoropiperidin-4-yl)-1H-indazol-3-amine
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|
C21H23F2N5
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0516638
|
8-[2-[(3R,4R)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H20F4N4O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0528719
|
[6-(3-fluoro-2-methylpyridin-4-yl)-5-methoxy-1H-indazol-3-yl]-(4-methylpiperazin-1-yl)methanone
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|
C20H22FN5O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0571523
|
6-(3-fluoro-2-methylpyridin-4-yl)-5-methoxy-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
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|
C20H24FN5O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0424067
|
8-[2-[(3S,4S)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H20F4N4O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0544570
|
6-(3-fluoro-2-methylpyridin-4-yl)-5-methyl-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C20H24FN5
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0575755
|
[6-(2,6-dimethylpyridin-4-yl)-5-methoxy-1H-indazol-3-yl]-(4-methylpiperazin-1-yl)methanone
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|
C21H25N5O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0531896
|
8-[2-piperidin-4-yl-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H21F3N4O
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0409319
|
8-(7-methyl-2-piperidin-4-ylindazol-5-yl)-2,3-dihydro-1H-indolizin-5-one
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|
C21H24N4O
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0575034
|
5-methoxy-6-(2-methoxypyridin-4-yl)-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C20H25N5O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0526851
|
5-methyl-7-(7-methyl-2-piperidin-4-ylindazol-5-yl)furo[3,2-c]pyridin-4-one
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|
C21H22N4O2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0562397
|
5-(7-cyclopropyl-2-piperidin-4-ylindazol-5-yl)-1,6-dimethylpyridin-2-one
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|
C22H26N4O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0409318
|
6-fluoro-1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C19H21FN4O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0526845
|
6-fluoro-1-methyl-5-[2-piperidin-4-yl-7-(trifluoromethyl)indazol-5-yl]pyridin-2-one
Show/Hide
|
C19H18F4N4O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0526841
|
1,6-dimethyl-5-[2-piperidin-4-yl-7-(trifluoromethyl)indazol-5-yl]pyridin-2-one
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|
C20H21F3N4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0571522
|
5-methoxy-N-(1-methylpiperidin-4-yl)-6-pyridin-4-yl-1H-indazol-3-amine
Show/Hide
|
C19H23N5O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0424057
|
6-chloro-1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C19H21ClN4O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0557738
|
5-(7-chloro-2-piperidin-4-ylindazol-5-yl)-1,6-dimethylpyridin-2-one
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|
C19H21ClN4O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0498368
|
(5-methoxy-6-pyridin-4-yl-1H-indazol-3-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0424056
|
1,3-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C20H24N4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0516639
|
8-[2-[(3S,4R)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
Show/Hide
|
C21H20F4N4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0553984
|
5-[2-[1-[2-(dimethylamino)acetyl]piperidin-4-yl]-7-methylindazol-5-yl]-1,6-dimethylpyridin-2-one
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0525568
|
1,6-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C20H24N4O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0424053
|
1-methyl-5-[8-methyl-2-(4-propan-2-ylpiperazin-1-yl)quinazolin-6-yl]pyridin-2-one
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0526842
|
1,6-dimethyl-5-[7-methyl-2-(1-methylpiperidin-4-yl)indazol-5-yl]pyridin-2-one
Show/Hide
|
C21H26N4O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0409314
|
1,4-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0531875
|
5-[2-(4-cyclobutylpiperazin-1-yl)quinazolin-6-yl]-1-methylpyridin-2-one
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
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CP0526843
|
1,6-dimethyl-5-(7-methyl-2-piperidin-3-ylindazol-5-yl)pyridin-2-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0424062
|
1,6-dimethyl-5-(7-methyl-2-pyridin-3-ylindazol-5-yl)pyridin-2-one
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|
C20H18N4O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
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CP0526844
|
5-[2-(4,4-difluoropiperidin-3-yl)-7-methylindazol-5-yl]-1,6-dimethylpyridin-2-one
Show/Hide
|
C20H22F2N4O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0409312
|
1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C19H22N4O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
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CP0531894
|
1-methyl-5-(2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C18H20N4O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
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CP0525563
|
1,6-dimethyl-5-[7-methyl-2-[1-(2,2,2-trifluoroethyl)piperidin-3-yl]indazol-5-yl]pyridin-2-one
Show/Hide
|
C22H25F3N4O
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0528718
|
5-methoxy-6-pyridin-4-yl-1H-indole
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|
C14H12N2O
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
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CP0424060
|
5-[2-(5,5-difluoropiperidin-3-yl)-7-methylindazol-5-yl]-1,6-dimethylpyridin-2-one
Show/Hide
|
C20H22F2N4O
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
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CP0141465
|
1-pentyl-4-(2-phenylmethoxyphenyl)imidazol-2-amine;hydrochloride
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|
C21H26ClN3O
|
1
|
| 1 |
IC50 = 8066.467694 nM
|
|
|
|
CP0580133
|
5-methoxy-6-pyridin-4-yl-1H-indazole
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|
C13H11N3O
|
1
|
| 1 |
IC50 > 9300 nM
|
|
|
