Brief Information of the Compound and Protein
Compound Name
5-cyclopropyl-6-(3-fluoro-2-methylpyridin-4-yl)-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
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PubChem ID
CID: 166633307
Canonical SMILES
CN1CCC(CC1)Nc1n[nH]c2cc(c(cc12)C1CC1)-c1ccnc(C)c1F
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Compound Formula C22H26FN5
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 0.08 nM
   TI
   LI
   LO
   TS