Brief Information of the Compound and Protein
Compound Name
4-(5-(6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)pentyl)piperidinium chloride
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PubChem ID
CID: 118727491
Canonical SMILES
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCC3CCNCC3)c2n1.Cl
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Compound Formula C19H33ClN6O2
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 57000 nM
   TI
   LI
   LO
   TS
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
Activity = 6.959343 nM
   TI
   LI
   LO
   TS