Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-methyl-7-(7-methyl-2-piperidin-4-ylindazol-5-yl)furo[3,2-c]pyridin-4-one
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 PubChem ID
CID: 153835384
Canonical SMILES
Cc1cc(cc2cn(nc12)C1CCNCC1)-c1cn(C)c(=O)c2ccoc12
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Compound Formula C21H22N4O2
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8.9 nM
   TI
   LI
   LO
   TS
CL000090 Schneider 2
 Cell Line Info 
Drosophila melanogaster (Fruit fly)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS