| Compound ID |
Compound Name |
Compound Formula |
|
CP0568471
|
4-N-butyl-6-[[4-[2-(dimethylamino)ethyl]phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H30N6
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0058460
|
5-(5-aminopentyl)-3-pentylquinolin-2-amine
Show/Hide
|
C19H29N3
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0489364
|
4-N-butyl-6-[[4-[(dimethylamino)methyl]phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C21H28N6
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0528674
|
4-N-butyl-6-[[4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C24H30N6O
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0431883
|
1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine
Show/Hide
|
C22H25N5
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0573940
|
4-N-butyl-6-[[4-(pyrrolidin-1-ylmethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C23H30N6
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0528677
|
6-[[4-[(dimethylamino)methyl]phenyl]methyl]-4-N-(2-methoxyethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H26N6O
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0568712
|
4-N-butyl-6-[[4-[(dimethylamino)methyl]-2-methoxyphenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H30N6O
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0458448
|
5-(4-aminobutyl)-3-pentylquinolin-2-amine
Show/Hide
|
C18H27N3
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0269934
|
4-N-butyl-5-[3-(1,3-dihydroisoindol-2-yl)propyl]-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C20H29N5
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0374594
|
5-[[4-(aminomethyl)phenyl]methyl]-3-pentylquinolin-2-amine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0576625
|
4-N-(2-methoxyethyl)-6-[[4-(pyrrolidin-1-ylmethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H28N6O
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0496496
|
4-N-butyl-6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C23H30N6O
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0425092
|
5-[[3-(aminomethyl)phenyl]methyl]-3-pentylquinolin-2-amine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 49 nM
|
|
|
|
CP0575146
|
4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]-N,N-dimethylbenzamide
Show/Hide
|
C21H26N6O
|
1
|
| 1 |
EC50 = 49 nM
|
|
|
|
CP0461930
|
7-(5-aminopentyl)-3-pentylquinolin-2-amine
Show/Hide
|
C19H29N3
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0528676
|
4-N-butyl-6-[[4-[(dimethylamino)methyl]-3-methoxyphenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H30N6O
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0576626
|
4-N-butyl-6-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H30N6O
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0372703
|
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine
Show/Hide
|
C22H25N5
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0431872
|
5-(6-aminohexyl)-3-pentylquinolin-2-amine
Show/Hide
|
C20H31N3
|
1
|
| 1 |
EC50 = 56 nM
|
|
|
|
CP0571145
|
4-N-butyl-6-[[3-[(dimethylamino)methyl]phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C21H28N6
|
1
|
| 1 |
EC50 = 59 nM
|
|
|
|
CP0374771
|
7-(4-aminobutyl)-3-pentylquinolin-2-amine
Show/Hide
|
C18H27N3
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0576627
|
[4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]phenyl]-pyrrolidin-1-ylmethanone
Show/Hide
|
C23H28N6O
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0573314
|
4-N-(2-methoxyethyl)-6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
EC50 = 75 nM
|
|
|
|
CP0461929
|
7-(6-aminohexyl)-3-pentylquinolin-2-amine
Show/Hide
|
C20H31N3
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
|
CP0487239
|
5-(3-aminopropyl)-3-pentylquinolin-2-amine
Show/Hide
|
C17H25N3
|
1
|
| 1 |
EC50 = 91 nM
|
|
|
|
CP0432826
|
4-N-butyl-6-methyl-5-[3-(4-phenylpiperazin-1-yl)propyl]pyrimidine-2,4-diamine
Show/Hide
|
C22H34N6
|
1
|
| 1 |
EC50 = 92 nM
|
|
|
|
CP0550014
|
4-N-butyl-6-[[4-(methoxymethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H25N5O
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0388784
|
1-(4-Amino-2-butyl-1H-imidazo-[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Show/Hide
|
C18H24N4O
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0569259
|
4-N-butyl-6-[[2-[(dimethylamino)methyl]phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C21H28N6
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0378706
|
4-N-butyl-6-methyl-5-(3-pyrrolidin-1-ylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H29N5
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0389372
|
4-[[4-(aminomethyl)phenyl]methyl]-3-pentylquinolin-2-amine;hydrochloride
Show/Hide
|
C22H28ClN3
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0533307
|
[4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]phenyl]methanol
Show/Hide
|
C19H23N5O
|
1
|
| 1 |
EC50 = 124 nM
|
|
|
|
CP0573268
|
4-N-butyl-6-[2-[4-[(dimethylamino)methyl]phenyl]ethyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H30N6
|
1
|
| 1 |
EC50 = 125 nM
|
|
|
|
CP0441187
|
4-N-butyl-5-[3-(dimethylamino)propyl]-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C14H27N5
|
1
|
| 1 |
EC50 = 126 nM
|
|
|
|
CP0378707
|
4-N-butyl-6-methyl-5-(4-morpholin-4-ylbutyl)pyrimidine-2,4-diamine
Show/Hide
|
C17H31N5O
|
1
|
| 1 |
EC50 = 128 nM
|
|
|
|
CP0528675
|
4-N-butyl-6-[[4-[(dimethylamino)methyl]phenyl]methyl]quinazoline-2,4-diamine
Show/Hide
|
C22H29N5
|
1
|
| 1 |
EC50 = 128 nM
|
|
|
|
CP0120000
|
4-N-butyl-6-methyl-5-(3-piperidin-1-ylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C17H31N5
|
1
|
| 1 |
EC50 = 133 nM
|
|
|
|
CP0569291
|
[4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]phenyl]-morpholin-4-ylmethanone
Show/Hide
|
C23H28N6O2
|
1
|
| 1 |
EC50 = 145 nM
|
|
|
|
CP0471662
|
4-[[3-(aminomethyl)phenyl]methyl]-3-pentylquinolin-2-amine;hydrochloride
Show/Hide
|
C22H28ClN3
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0378716
|
4-N-butyl-6-methyl-5-(3-thiomorpholin-4-ylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H29N5S
|
1
|
| 1 |
EC50 = 167 nM
|
|
|
|
CP0441193
|
5-[3-(azepan-1-yl)propyl]-4-N-butyl-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C18H33N5
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0378714
|
4-N-butyl-6-methyl-5-[3-(4-methylpiperazin-1-yl)propyl]pyrimidine-2,4-diamine
Show/Hide
|
C17H32N6
|
1
|
| 1 |
EC50 = 179 nM
|
|
|
|
CP0458450
|
4-(4-aminobutyl)-3-pentylquinolin-2-amine;hydrochloride
Show/Hide
|
C18H28ClN3
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0561996
|
3-pentylquinolin-2-amine
Show/Hide
|
C14H18N2
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0389715
|
4-N-butyl-5-[3-[2-methoxyethyl(methyl)amino]propyl]-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C16H31N5O
|
1
|
| 1 |
EC50 = 203 nM
|
|
|
|
CP0384861
|
4-(5-aminopentyl)-3-pentylquinolin-2-amine;hydrochloride
Show/Hide
|
C19H30ClN3
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0389721
|
4-N-butyl-5-[3-(diethylamino)propyl]-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C16H31N5
|
1
|
| 1 |
EC50 = 254 nM
|
|
|
|
CP0389723
|
4-N-butyl-6-methyl-5-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H29N5O
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0406892
|
tert-butyl 4-[3-[2-amino-4-(butylamino)-6-methylpyrimidin-5-yl]propyl]piperazine-1-carboxylate
Show/Hide
|
C21H38N6O2
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0224537
|
5-(4-aminobutyl)-4-N-butyl-6-methylpyrimidine-2,4-diamine;dihydrochloride
Show/Hide
|
C13H27Cl2N5
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0578056
|
5-(5-aminopentyl)-4-N-butyl-6-methylpyrimidine-2,4-diamine;dihydrochloride
Show/Hide
|
C14H29Cl2N5
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0097851
|
4-N-butyl-6-methyl-5-[3-(2-methylbenzimidazol-1-yl)propyl]pyrimidine-2,4-diamine
Show/Hide
|
C20H28N6
|
1
|
| 1 |
EC50 = 366 nM
|
|
|
|
CP0391348
|
[3-(3-fluoroanilino)-7-methyl-2-(pentylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C20H24FN3O2
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0378724
|
2-[3-[2-amino-4-(butylamino)-6-methylpyrimidin-5-yl]propyl]isoindole-1,3-dione
Show/Hide
|
C20H25N5O2
|
1
|
| 1 |
EC50 = 453 nM
|
|
|
|
CP0233638
|
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
Show/Hide
|
C17H22N4O2
|
6
|
| 1 |
EC50 = 480 nM
|
|
|
| 2 |
EC50 = 4000 nM
|
|
|
| 3 |
EC50 = 4500 nM
|
|
|
| 4 |
EC50 = 5870 nM
|
|
|
| 5 |
EC50 = 6130 nM
|
|
|
| 6 |
EC50 = 6400 nM
|
|
|
|
CP0847786
|
N4-Butyl-6-methyl-5-(3-(piperazin-1-yl)propyl)pyrimidine-2,4-diamine trihydrochloride
Show/Hide
|
C16H33Cl3N6
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0569171
|
4-N-butyl-6-[[4-(diethoxyphosphorylmethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C23H32N5O3P
|
1
|
| 1 |
EC50 = 501 nM
|
|
|
|
CP0406388
|
6-(5-aminopentyl)-3-pentylquinolin-2-amine
Show/Hide
|
C19H29N3
|
1
|
| 1 |
EC50 = 519 nM
|
|
|
|
CP0551606
|
4-N-butyl-6-[[4-(methylaminomethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H26N6
|
1
|
| 1 |
EC50 = 580 nM
|
|
|
|
CP0496501
|
4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzoic acid
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 620 nM
|
|
|
|
CP0487238
|
5,7-bis(5-aminopentyl)-3-pentylquinolin-2-amine
Show/Hide
|
C24H40N4
|
1
|
| 1 |
EC50 = 621 nM
|
|
|
|
CP0496494
|
4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzonitrile
Show/Hide
|
C19H20N6
|
1
|
| 1 |
EC50 = 660 nM
|
|
|
|
CP0540765
|
5-[4-(aminomethyl)phenyl]-3-pentylquinolin-2-amine
Show/Hide
|
C21H25N3
|
1
|
| 1 |
EC50 = 699 nM
|
|
|
|
CP0417236
|
6-(4-aminobutyl)-3-pentylquinolin-2-amine
Show/Hide
|
C18H27N3
|
1
|
| 1 |
EC50 = 727 nM
|
|
|
|
CP0378694
|
4-N-butyl-6-methyl-5-(3-phenylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C18H26N4
|
1
|
| 1 |
EC50 = 749 nM
|
|
|
|
CP0550015
|
3-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzonitrile
Show/Hide
|
C19H20N6
|
1
|
| 1 |
EC50 = 750 nM
|
|
|
|
CP0378704
|
4-N,5-dibutyl-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C13H24N4
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0546425
|
6-benzyl-4-N-(2-methoxyethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
|
CP0378705
|
4-N-butyl-6-methyl-5-(5-phenylpentyl)pyrimidine-2,4-diamine
Show/Hide
|
C20H30N4
|
1
|
| 1 |
EC50 = 830 nM
|
|
|
|
CP0480859
|
[7-methyl-3-(3-nitroanilino)-2-(pentylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C20H24N4O4
|
1
|
| 1 |
EC50 = 850 nM
|
|
|
|
CP0441185
|
4-N-butyl-6-methyl-5-(4-phenylbutyl)pyrimidine-2,4-diamine
Show/Hide
|
C19H28N4
|
1
|
| 1 |
EC50 = 857 nM
|
|
|
|
CP0496497
|
6-benzyl-4-N-butylpyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H21N5
|
1
|
| 1 |
EC50 = 950 nM
|
|
|
|
CP0573267
|
6-[[4-(aminomethyl)phenyl]methyl]-4-N-butylpyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H24N6
|
1
|
| 1 |
EC50 = 960 nM
|
|
|
|
CP0458449
|
5-[[2-(aminomethyl)phenyl]methyl]-3-pentylquinolin-2-amine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0374772
|
6-(6-aminohexyl)-3-pentylquinolin-2-amine
Show/Hide
|
C20H31N3
|
1
|
| 1 |
EC50 = 1016 nM
|
|
|
|
CP0378711
|
4-N-butyl-6-methyl-5-[3-(1,2,4-triazol-1-yl)propyl]pyrimidine-2,4-diamine
Show/Hide
|
C14H23N7
|
1
|
| 1 |
EC50 = 1050 nM
|
|
|
|
CP0378723
|
4-N-butyl-6-methyl-5-(3-pyrazol-1-ylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C15H24N6
|
1
|
| 1 |
EC50 = 1050 nM
|
|
|
|
CP0496495
|
4-N-butyl-6-[(4-methylphenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H23N5
|
1
|
| 1 |
EC50 = 1080 nM
|
|
|
|
CP0378722
|
4-N-butyl-5-(3-indol-1-ylpropyl)-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C20H27N5
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0550012
|
4-N-butyl-6-(1-phenylethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H23N5
|
1
|
| 1 |
EC50 = 1127 nM
|
|
|
|
CP0052666
|
4-methyl-1-pentylbenzimidazol-2-amine
Show/Hide
|
C13H19N3
|
2
|
| 1 |
EC50 = 1130 nM
|
|
|
| 2 |
EC50 = 1800 nM
|
|
|
|
CP0546370
|
6-[[2-(aminomethyl)phenyl]methyl]-4-N-butylpyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H24N6
|
1
|
| 1 |
EC50 = 1150 nM
|
|
|
|
CP0389719
|
4-N-butyl-6-methyl-5-(2-phenylethyl)pyrimidine-2,4-diamine
Show/Hide
|
C17H24N4
|
1
|
| 1 |
EC50 = 1190 nM
|
|
|
|
CP0378720
|
5-benzyl-4-N-butyl-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C16H22N4
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0569172
|
4-N-butyl-6-[[4-[(2,2,2-trifluoroethylamino)methyl]phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C21H25F3N6
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0378702
|
5-[2-amino-4-(butylamino)-6-methylpyrimidin-5-yl]-2-methylpentan-2-ol
Show/Hide
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C15H28N4O
|
1
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| 1 |
EC50 = 1220 nM
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CP0389724
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4-N-butyl-6-methyl-5-pentylpyrimidine-2,4-diamine
Show/Hide
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C14H26N4
|
1
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| 1 |
EC50 = 1220 nM
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CP0576624
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4-N-butyl-6-[(2-methylphenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H23N5
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1
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| 1 |
EC50 = 1248 nM
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CP0496499
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2-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzonitrile
Show/Hide
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C19H20N6
|
1
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| 1 |
EC50 = 1280 nM
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CP0378700
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4-[2-amino-4-(butylamino)-6-methylpyrimidin-5-yl]butan-1-ol
Show/Hide
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C13H24N4O
|
1
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| 1 |
EC50 = 1310 nM
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CP0085572
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2-propyl-[1,3]thiazolo[4,5-c]quinolin-4-amine
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C13H13N3S
|
1
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| 1 |
EC50 = 1320 nM
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CP0471336
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4-(2-chlorophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C14H19Cl2N3
|
1
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| 1 |
EC50 = 1360 nM
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CP0575148
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4-N-butyl-6-[(4-methoxyphenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H23N5O
|
1
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| 1 |
EC50 = 1390 nM
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CP0569661
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methyl 4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzoate
Show/Hide
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C20H23N5O2
|
1
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| 1 |
EC50 = 1400 nM
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CP0551612
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4-N-butyl-6-[(3-methylphenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H23N5
|
1
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| 1 |
EC50 = 1440 nM
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CP0434076
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methyl 4-amino-2-butyl-1-[(2R)-2-hydroxypropyl]imidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
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C19H24N4O3
|
1
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| 1 |
EC50 = 1500 nM
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CP0422875
|
4-(2,5-dimethylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C16H24ClN3
|
1
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| 1 |
EC50 = 1500 nM
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CP0422884
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4-(2,4-dimethylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C16H24ClN3
|
1
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| 1 |
EC50 = 1500 nM
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CP0422886
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4-(2-methoxy-3-methylphenyl)-1-pentylimidazol-2-amine;hydrochloride
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C16H24ClN3O
|
1
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| 1 |
EC50 = 1500 nM
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CP0486491
|
4-(2,3-dimethylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C16H24ClN3
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1
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| 1 |
EC50 = 1500 nM
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CP0511743
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4-naphthalen-1-yl-1-pentylimidazol-2-amine;hydrochloride
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C18H22ClN3
|
1
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| 1 |
EC50 = 1500 nM
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CP0514784
|
4-(4-methoxy-2-methylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C16H24ClN3O
|
1
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| 1 |
EC50 = 1500 nM
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CP0489380
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4-N-butyl-6-[(2-fluorophenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C18H20FN5
|
1
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| 1 |
EC50 = 1501 nM
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CP0568473
|
4-N-butyl-6-(2-phenylethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H23N5
|
1
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| 1 |
EC50 = 1504 nM
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CP0422890
|
4-(2-methoxyphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C15H22ClN3O
|
1
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| 1 |
EC50 = 1600 nM
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CP0135788
|
4-N-butyl-5-iodo-6-methylpyrimidine-2,4-diamine
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C9H15IN4
|
1
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| 1 |
EC50 = 1640 nM
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CP0422871
|
1-pentyl-4-[2-(trifluoromethyl)phenyl]imidazol-2-amine;hydrochloride
Show/Hide
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C15H19ClF3N3
|
1
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| 1 |
EC50 = 1640 nM
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CP0375356
|
4-ethyl-1-pentylbenzimidazol-2-amine
Show/Hide
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C14H21N3
|
1
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| 1 |
EC50 = 1650 nM
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CP0378698
|
4-N-butyl-5-ethyl-6-methylpyrimidine-2,4-diamine
Show/Hide
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C11H20N4
|
1
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| 1 |
EC50 = 1660 nM
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CP0573939
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methyl 3-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzoate
Show/Hide
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C20H23N5O2
|
1
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| 1 |
EC50 = 1666 nM
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CP0497853
|
[3-anilino-2-(benzylamino)-7-methylfuro[2,3-c]pyridin-4-yl]methanol
Show/Hide
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C22H21N3O2
|
1
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| 1 |
EC50 = 1680 nM
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CP0496498
|
4-N-butyl-6-[[2-(trifluoromethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H20F3N5
|
1
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| 1 |
EC50 = 1680 nM
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CP0859646
|
4-((6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)methyl)piperidinium chloride
Show/Hide
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C15H25ClN6O2
|
1
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| 1 |
EC50 = 1800 nM
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CP0422888
|
1-pentyl-4-(2-phenylethyl)imidazol-2-amine;hydrochloride
Show/Hide
|
C16H24ClN3
|
1
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| 1 |
EC50 = 1800 nM
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CP0538120
|
4-(3-chlorophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C14H19Cl2N3
|
1
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| 1 |
EC50 = 1930 nM
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CP0422882
|
4-(4-fluorophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
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C14H19ClFN3
|
1
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| 1 |
EC50 = 1960 nM
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CP0471344
|
1-pentyl-4-[3-(trifluoromethyl)phenyl]imidazol-2-amine;hydrochloride
Show/Hide
|
C15H19ClF3N3
|
1
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| 1 |
EC50 = 1980 nM
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CP0486490
|
4-(3-methylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H22ClN3
|
1
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| 1 |
EC50 = 2000 nM
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CP0422880
|
4-(4-fluoro-2-methylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H21ClFN3
|
1
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| 1 |
EC50 = 2010 nM
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CP0551605
|
4-N-butyl-6-[[4-(trifluoromethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H20F3N5
|
1
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| 1 |
EC50 = 2035 nM
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CP0870709
|
6-amino-9-[[1-(2-aminoethyl)-4-piperidyl]methyl]-2-[(1S)-1-methylbutoxy]-7H-purin-8-one Hydrochloride
Show/Hide
|
C18H32ClN7O2
|
1
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| 1 |
EC50 = 2130 nM
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CP0859644
|
6-amino-9-[[1-(2-hydroxyethyl)-4-piperidyl]methyl]-2-[(1S)-1-methylbutoxy]-7H-purin-8-one Hydrochloride
Show/Hide
|
C18H31ClN6O3
|
1
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| 1 |
EC50 = 2140 nM
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CP0540764
|
4-(2-amino-3-pentylquinolin-5-yl)butanamide
Show/Hide
|
C18H25N3O
|
1
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| 1 |
EC50 = 2181 nM
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CP0531209
|
4-(3-methoxyphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H22ClN3O
|
1
|
| 1 |
EC50 = 2200 nM
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CP0476287
|
methyl 4-amino-1-(5-aminopentyl)-2-butylimidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C21H29N5O2
|
1
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| 1 |
EC50 = 2210 nM
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CP0544424
|
[3-anilino-7-methyl-2-(pentylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C20H25N3O2
|
1
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| 1 |
EC50 = 2250 nM
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CP0569170
|
methyl 2-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzoate
Show/Hide
|
C20H23N5O2
|
1
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| 1 |
EC50 = 2280 nM
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CP0421605
|
5-(3-aminopropyl)-4-N-butyl-6-methylpyrimidine-2,4-diamine;dihydrochloride
Show/Hide
|
C12H25Cl2N5
|
1
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| 1 |
EC50 = 2310 nM
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CP0472983
|
5-(5-aminopentyl)-4-N-butyl-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C19H29N5
|
1
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| 1 |
EC50 = 2350 nM
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CP0422878
|
4-(2-fluorophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C14H19ClFN3
|
1
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| 1 |
EC50 = 2350 nM
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CP0422872
|
1-pentyl-4-phenylimidazol-2-amine;hydrochloride
Show/Hide
|
C14H20ClN3
|
1
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| 1 |
EC50 = 2480 nM
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CP0471345
|
1-pentyl-4-[4-(trifluoromethyl)phenyl]imidazol-2-amine;hydrochloride
Show/Hide
|
C15H19ClF3N3
|
1
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| 1 |
EC50 = 2480 nM
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CP0422870
|
4-(2,6-dimethylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C16H24ClN3
|
1
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| 1 |
EC50 = 2500 nM
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CP0422873
|
4-(2-ethylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C16H24ClN3
|
1
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| 1 |
EC50 = 2500 nM
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CP0422874
|
4-(4-methylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H22ClN3
|
1
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| 1 |
EC50 = 2500 nM
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CP0422883
|
4-(2-methylphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H22ClN3
|
1
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| 1 |
EC50 = 2500 nM
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CP0487709
|
4-(2,3-dimethoxyphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C16H24ClN3O2
|
1
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| 1 |
EC50 = 2500 nM
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CP0859645
|
6-amino-2-[(1S)-1-methylbutoxy]-9-(4-piperidylmethyl)-7H-purin-8-one Hydrochloride
Show/Hide
|
C16H27ClN6O2
|
1
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| 1 |
EC50 = 2530 nM
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CP0422879
|
4-(3-fluorophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C14H19ClFN3
|
1
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| 1 |
EC50 = 2570 nM
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CP0569064
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4-N-butyl-6-[(4-fluorophenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H20FN5
|
1
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| 1 |
EC50 = 2625 nM
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CP0505005
|
methyl 4-amino-2-butyl-1-[(2S)-2-hydroxypropyl]imidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C19H24N4O3
|
1
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| 1 |
EC50 = 2700 nM
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CP0232352
|
5-(4-aminobutyl)-4-N-butyl-6-phenylpyrimidine-2,4-diamine;dihydrochloride
Show/Hide
|
C18H29Cl2N5
|
1
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| 1 |
EC50 = 2700 nM
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CP0563899
|
4-benzyl-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H22ClN3
|
1
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| 1 |
EC50 = 2700 nM
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CP0573265
|
4-N-butyl-6-[(3-fluorophenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H20FN5
|
1
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| 1 |
EC50 = 2850 nM
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CP0431871
|
2-[4-(2-amino-3-pentylquinolin-5-yl)butyl]guanidine
Show/Hide
|
C19H29N5
|
1
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| 1 |
EC50 = 2862 nM
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CP0568476
|
6-[[4-(azidomethyl)phenyl]methyl]-4-N-butylpyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H22N8
|
1
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| 1 |
EC50 = 2870 nM
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CP0487708
|
4-(4-methoxyphenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C15H22ClN3O
|
1
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| 1 |
EC50 = 2940 nM
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CP0569173
|
[4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]phenyl]methyl-trimethylazanium;chloride
Show/Hide
|
C22H31ClN6
|
1
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| 1 |
EC50 = 3000 nM
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CP0471335
|
1-pentyl-4-(3,4,5-trimethoxyphenyl)imidazol-2-amine;hydrochloride
Show/Hide
|
C17H26ClN3O3
|
1
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| 1 |
EC50 = 3080 nM
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CP0378701
|
4-[2-amino-4-(butylamino)-6-methylpyrimidin-5-yl]-2-methylbutan-2-ol
Show/Hide
|
C14H26N4O
|
1
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| 1 |
EC50 = 3140 nM
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CP0386903
|
3-pentylbenzo[e]benzimidazol-2-amine
Show/Hide
|
C16H19N3
|
1
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| 1 |
EC50 = 3160 nM
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CP0400244
|
1-pentylbenzimidazol-2-amine
Show/Hide
|
C12H17N3
|
1
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| 1 |
EC50 = 3230 nM
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CP0573262
|
4-N-butyl-6-[(2-methoxyphenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H23N5O
|
1
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| 1 |
EC50 = 3267 nM
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CP0378719
|
4-N-butyl-5,6-dimethylpyrimidine-2,4-diamine
Show/Hide
|
C10H18N4
|
1
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| 1 |
EC50 = 3280 nM
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CP0497852
|
[2-[6-[[4-(hydroxymethyl)-7-methyl-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-2-yl]amino]hexylamino]-7-methyl-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C34H38N8O4
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1
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| 1 |
EC50 = 3370 nM
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CP0538126
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5-iodo-6-methyl-4-N-pentylpyrimidine-2,4-diamine
Show/Hide
|
C10H17IN4
|
1
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| 1 |
EC50 = 3700 nM
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CP0400245
|
4-methoxy-1-pentylbenzimidazol-2-amine
Show/Hide
|
C13H19N3O
|
1
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| 1 |
EC50 = 3740 nM
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CP0389720
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4-N-butyl-6-methyl-5-(3-piperidin-1-ylprop-1-ynyl)pyrimidine-2,4-diamine
Show/Hide
|
C17H27N5
|
1
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| 1 |
EC50 = 3790 nM
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CP0403319
|
methyl 4-amino-1-(4-aminobutyl)-2-butylimidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C20H27N5O2
|
1
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| 1 |
EC50 = 3850 nM
|
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CP0375337
|
1-hexylbenzimidazol-2-amine
Show/Hide
|
C13H19N3
|
1
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| 1 |
EC50 = 3960 nM
|
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CP0575147
|
4-N-butyl-6-[(3-methoxyphenyl)methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H23N5O
|
1
|
| 1 |
EC50 = 4000 nM
|
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CP0471340
|
methyl 4-(2-amino-1-pentylimidazol-4-yl)benzoate;hydrochloride
Show/Hide
|
C16H22ClN3O2
|
1
|
| 1 |
EC50 = 4040 nM
|
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CP0498118
|
[7-methyl-2-[[(1S)-1-phenylethyl]amino]-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C22H22N4O2
|
1
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| 1 |
EC50 = 4270 nM
|
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CP0461771
|
methyl 4-amino-2-butyl-1-(2-hydroxyethyl)imidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C18H22N4O3
|
2
|
| 1 |
EC50 = 4400 nM
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| 2 |
EC50 = 37000 nM
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CP0375354
|
5-methyl-1-pentylbenzimidazol-2-amine
Show/Hide
|
C13H19N3
|
1
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| 1 |
EC50 = 4570 nM
|
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CP0389765
|
methyl 4-amino-2-butyl-1-(2-hydroxypropyl)imidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C19H24N4O3
|
2
|
| 1 |
EC50 = 4900 nM
|
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| 2 |
EC50 = 9880 nM
|
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CP0389717
|
4-N-butyl-5-ethynyl-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C11H16N4
|
1
|
| 1 |
EC50 = 4900 nM
|
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CP0508512
|
[2-(benzylamino)-7-methyl-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C21H20N4O2
|
1
|
| 1 |
EC50 = 4910 nM
|
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CP0507201
|
[7-methyl-3-(pyridin-2-ylamino)-2-(trimethylsilylmethylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C18H24N4O2Si
|
1
|
| 1 |
EC50 = 4990 nM
|
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CP0476442
|
4-N-butyl-6-methyl-5-pent-1-ynylpyrimidine-2,4-diamine
Show/Hide
|
C14H22N4
|
1
|
| 1 |
EC50 = 5000 nM
|
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CP0375358
|
2-amino-1-pentylbenzimidazol-4-ol
Show/Hide
|
C12H17N3O
|
1
|
| 1 |
EC50 = 5010 nM
|
|
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CP0487039
|
2-(2-amino-1-pentylimidazol-4-yl)phenol;hydrochloride
Show/Hide
|
C14H20ClN3O
|
1
|
| 1 |
EC50 = 5100 nM
|
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CP0568474
|
methyl 4-[2-[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]ethyl]benzoate
Show/Hide
|
C21H25N5O2
|
1
|
| 1 |
EC50 = 5230 nM
|
|
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CP0486405
|
methyl 4-amino-1-[[4-(aminomethyl)phenyl]methyl]-2-butylimidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
EC50 = 5340 nM
|
|
|
|
CP0517627
|
[7-methyl-2-(pentylamino)-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
EC50 = 5810 nM
|
|
|
|
CP0375361
|
1-pentylbenzimidazole-2,4-diamine
Show/Hide
|
C12H18N4
|
1
|
| 1 |
EC50 = 6600 nM
|
|
|
|
CP0386819
|
7-methyl-1-pentylbenzimidazol-2-amine
Show/Hide
|
C13H19N3
|
1
|
| 1 |
EC50 = 6610 nM
|
|
|
|
CP0224536
|
4-N-butyl-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C14H18N4
|
1
|
| 1 |
EC50 = 6700 nM
|
|
|
|
CP0422877
|
4-(4-chlorophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C14H19Cl2N3
|
1
|
| 1 |
EC50 = 6830 nM
|
|
|
|
CP0543289
|
[2-(cyclohexylamino)-7-methyl-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C20H24N4O2
|
1
|
| 1 |
EC50 = 6930 nM
|
|
|
|
CP0375360
|
4-N,4-N-dimethyl-1-pentylbenzimidazole-2,4-diamine
Show/Hide
|
C14H22N4
|
1
|
| 1 |
EC50 = 7120 nM
|
|
|
|
CP0433985
|
methyl 4-amino-1-(2-hydroxy-2-methylpropyl)-2-pentylimidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
EC50 = 7200 nM
|
|
|
|
CP0375355
|
6-methyl-1-pentylbenzimidazol-2-amine
Show/Hide
|
C13H19N3
|
1
|
| 1 |
EC50 = 7210 nM
|
|
|
|
CP0397087
|
(1-butylbenzimidazol-2-yl)amine;hydrochloride
Show/Hide
|
C11H15N3
|
1
|
| 1 |
EC50 = 7300 nM
|
|
|
|
CP0413835
|
tert-butyl 3-[[4-(hydroxymethyl)-7-methyl-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-2-yl]amino]propanoate
Show/Hide
|
C21H26N4O4
|
1
|
| 1 |
EC50 = 7640 nM
|
|
|
|
CP0552244
|
4-(4-aminophenyl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C14H21ClN4
|
1
|
| 1 |
EC50 = 8000 nM
|
|
|
|
CP0422885
|
[2-(2-amino-1-pentylimidazol-4-yl)phenyl]methanol;hydrochloride
Show/Hide
|
C15H22ClN3O
|
1
|
| 1 |
EC50 = 8050 nM
|
|
|
|
CP0483384
|
5-bromo-4-N-butyl-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C9H15BrN4
|
1
|
| 1 |
EC50 = 8500 nM
|
|
|
|
CP0486956
|
[7-methyl-2-(pentan-2-ylamino)-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
EC50 = 9010 nM
|
|
|
|
CP0378709
|
4-N-butyl-6-methyl-5-(2-trimethylsilylethynyl)pyrimidine-2,4-diamine
Show/Hide
|
C14H24N4Si
|
1
|
| 1 |
EC50 = 9240 nM
|
|
|
|
CP0480858
|
[2-(butylamino)-7-methyl-3-(pyridin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
EC50 = 9380 nM
|
|
|
|
CP0523692
|
[2-(benzylamino)-7-methyl-3-(pyrazin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C20H19N5O2
|
1
|
| 1 |
EC50 = 9790 nM
|
|
|
|
CP0523684
|
[2-(cyclohexylamino)-7-methyl-3-(pyrazin-2-ylamino)furo[2,3-c]pyridin-4-yl]methanol
Show/Hide
|
C19H23N5O2
|
1
|
| 1 |
EC50 = 10580 nM
|
|
|
|
CP0422889
|
methyl 2-(2-amino-1-pentylimidazol-4-yl)benzoate;hydrochloride
Show/Hide
|
C16H22ClN3O2
|
1
|
| 1 |
EC50 = 11100 nM
|
|
|
|
CP0402138
|
6-amino-2-butoxy-9-[[1-(2-hydroxyethyl)piperidin-4-yl]methyl]-7H-purin-8-one;hydrochloride
Show/Hide
|
C17H29ClN6O3
|
1
|
| 1 |
EC50 = 12500 nM
|
|
|
|
CP0437656
|
6-amino-9-[[1-(2-aminoethyl)piperidin-4-yl]methyl]-2-butoxy-7H-purin-8-one;hydrochloride
Show/Hide
|
C17H30ClN7O2
|
1
|
| 1 |
EC50 = 13000 nM
|
|
|
|
CP0550013
|
[4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]phenyl]methylphosphonic acid
Show/Hide
|
C19H24N5O3P
|
1
|
| 1 |
EC50 = 13500 nM
|
|
|
|
CP0496500
|
2-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzoic acid
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 13600 nM
|
|
|
|
CP0573266
|
4-N-butyl-6-[[3-(trifluoromethyl)phenyl]methyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H20F3N5
|
1
|
| 1 |
EC50 = 14000 nM
|
|
|
|
CP0489353
|
6-benzyl-4-N-butylpteridine-2,4-diamine
Show/Hide
|
C17H20N6
|
1
|
| 1 |
EC50 = 15000 nM
|
|
|
|
CP0378696
|
4-N-butyl-6-methyl-5-(3-morpholin-4-ylprop-1-ynyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H25N5O
|
1
|
| 1 |
EC50 = 16200 nM
|
|
|
|
CP0546368
|
3-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]benzoic acid
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 16500 nM
|
|
|
|
CP0422237
|
4-(3,5-dimethyl-1,2-oxazol-4-yl)-1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C13H21ClN4O
|
1
|
| 1 |
EC50 = 18800 nM
|
|
|
|
CP0468725
|
4-N-butyl-5-chloro-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C9H15ClN4
|
1
|
| 1 |
EC50 = 20000 nM
|
|
|
|
CP0422876
|
4-(2-amino-1-pentylimidazol-4-yl)benzamide;hydrochloride
Show/Hide
|
C15H21ClN4O
|
1
|
| 1 |
EC50 = 20240 nM
|
|
|
|
CP0379915
|
methyl 4-amino-2-butyl-1-(2-hydroxy-2-methylpropyl)imidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C20H26N4O3
|
3
|
| 1 |
EC50 = 20860 nM
|
|
|
| 2 |
EC50 = 41300 nM
|
|
|
| 3 |
EC50 = 49600 nM
|
|
|
|
CP0422235
|
1-pentyl-4-pyridin-3-ylimidazol-2-amine;hydrochloride
Show/Hide
|
C13H19ClN4
|
1
|
| 1 |
EC50 = 21310 nM
|
|
|
|
CP0426639
|
4-N-butyl-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C9H16N4
|
1
|
| 1 |
EC50 = 22000 nM
|
|
|
|
CP0544699
|
4-N-butyl-6-(4-methoxyphenyl)pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H21N5O
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0568470
|
4-N-butyl-6-phenylpyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C17H19N5
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0568472
|
6-benzyl-4-butylsulfanylpyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C18H20N4S
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0568475
|
4-N-butyl-6-[(E)-2-phenylethenyl]pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0568701
|
6-benzyl-4-piperidin-1-ylpyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0569660
|
6-benzyl-4-N-butyl-4-N-methylpyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C19H23N5
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0573264
|
6-benzyl-4-butoxypyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C18H20N4O
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0573937
|
6-benzyl-4-morpholin-4-ylpyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C18H19N5O
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0576623
|
4-N-butyl-6-(naphthalen-2-ylmethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H23N5
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0562874
|
methyl 4-amino-1-(3-aminopropyl)-2-butylimidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C19H25N5O2
|
1
|
| 1 |
EC50 = 26700 nM
|
|
|
|
CP0422887
|
1-pentylimidazol-2-amine;hydrochloride
Show/Hide
|
C8H16ClN3
|
1
|
| 1 |
EC50 = 28400 nM
|
|
|
|
CP0864483
|
4-(6-(6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)hexyl)piperidinium chloride
Show/Hide
|
C20H35ClN6O2
|
1
|
| 1 |
EC50 = 29000 nM
|
|
|
|
CP0471265
|
methyl 4-amino-2-butyl-1-(2-phenylmethoxyethyl)imidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
EC50 = 31000 nM
|
|
|
|
CP0468726
|
4-N-butyl-5-fluoro-6-methylpyrimidine-2,4-diamine
Show/Hide
|
C9H15FN4
|
1
|
| 1 |
EC50 = 34000 nM
|
|
|
|
CP0394356
|
methyl 4-amino-1-(2-aminoethyl)-2-butylimidazo[4,5-c]quinoline-7-carboxylate
Show/Hide
|
C18H23N5O2
|
1
|
| 1 |
EC50 = 49800 nM
|
|
|
|
CP0859647
|
4-(5-(6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)pentyl)piperidinium chloride
Show/Hide
|
C19H33ClN6O2
|
1
|
| 1 |
EC50 = 57000 nM
|
|
|
|
CP0530280
|
4-N-butylpyrimidine-2,4-diamine
Show/Hide
|
C8H14N4
|
1
|
| 1 |
EC50 = 73200 nM
|
|
|
|
CP0579429
|
US10660877, Example 31
Show/Hide
|
C23H29N3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0574442
|
US10660877, Example 73
Show/Hide
|
C22H26FN3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0576818
|
US10660877, Example 83
Show/Hide
|
C21H23F2N3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0543450
|
US10660877, Example 77
Show/Hide
|
C23H28FN3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0950854
|
2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C23H29N3
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0543454
|
2-(2-fluoro-6-methylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C22H26FN3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0543452
|
US10660877, Example 5
Show/Hide
|
C22H27N3
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0543448
|
US10660877, Example 38
Show/Hide
|
C21H25N3
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0568585
|
US10660877, Example 19
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0568589
|
US10660877, Example 46
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0575860
|
US10660877, Example 63
Show/Hide
|
C21H25N3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0543449
|
US10660877, Example 39
Show/Hide
|
C24H31N3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0543453
|
US10660877, Example 30
Show/Hide
|
C23H29N3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0569162
|
US10660877, Example 82
Show/Hide
|
C22H27N3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0578452
|
US10660877, Example 23
Show/Hide
|
C22H27N3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0568586
|
2-(2-cyclopropyl-6-methylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C25H31N3
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0568588
|
2-(2-ethyl-6-methylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C24H31N3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0571722
|
US10660877, Example 22
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0547009
|
3-isopropyl-2-(2-methoxypyridin-4-yl)-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0571037
|
2-(2-cyclopropylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C24H29N3
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0547004
|
US10660877, Example 6
Show/Hide
|
C22H24F3N3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0579792
|
US10660877, Example 75
Show/Hide
|
C23H29N3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0543455
|
US10660877, Example 776
Show/Hide
|
C22H28N4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0547005
|
US10660877, Example 43
Show/Hide
|
C25H33N3
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0476472
|
2-[4-(3-iodo-2-nitrophenoxy)phenyl]-1,3,4-oxadiazole
Show/Hide
|
C14H8IN3O4
|
3
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
IC50 = 620 nM
|
|
|
| 3 |
Kd = 85.5 nM
|
|
|
|
CP0547011
|
US10660877, Example 74
Show/Hide
|
C23H26F3N3
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0388427
|
2-[4-[2-(3,4-dimethoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0577540
|
2-[4-[2-(5-methoxypyridin-3-yl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0493523
|
2-[4-(3-chloro-2-nitrophenoxy)phenyl]-1,3,4-oxadiazole
Show/Hide
|
C14H8ClN3O4
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0438453
|
2-bromo-6-[4-(1,3,4-oxadiazol-2-yl)phenoxy]benzonitrile
Show/Hide
|
C15H8BrN3O2
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0578600
|
US10660877, Example 81
Show/Hide
|
C21H24FN3
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
|
CP0438454
|
N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodobenzamide
Show/Hide
|
C21H11F7INO2
|
1
|
| 1 |
IC50 = 1040 nM
|
|
|
|
CP0534467
|
N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-5-chloro-2-fluorobenzamide
Show/Hide
|
C21H11ClF7NO2
|
1
|
| 1 |
IC50 = 1110 nM
|
|
|
|
CP0547003
|
US10660877, Example 777
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0014940
|
2-chloro-6-[4-(1,3,4-oxadiazol-2-yl)phenoxy]benzonitrile
Show/Hide
|
C15H8ClN3O2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0438456
|
2-chloro-6-fluoro-N-[4-[3-fluoro-5-(trifluoromethyl)phenoxy]phenyl]benzamide
Show/Hide
|
C20H11ClF5NO2
|
1
|
| 1 |
IC50 = 1590 nM
|
|
|
|
CP0438452
|
N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-chloro-6-fluorobenzamide
Show/Hide
|
C21H11ClF7NO2
|
1
|
| 1 |
IC50 = 1640 nM
|
|
|
|
CP0470767
|
2-chloro-N-[4-[3-chloro-5-(trifluoromethyl)phenoxy]phenyl]-6-fluorobenzamide
Show/Hide
|
C20H11Cl2F4NO2
|
1
|
| 1 |
IC50 = 2040 nM
|
|
|
|
CP0533371
|
N-[4-[3-bromo-5-(trifluoromethyl)phenoxy]phenyl]-2-chloro-6-fluorobenzamide
Show/Hide
|
C20H11BrClF4NO2
|
1
|
| 1 |
IC50 = 2320 nM
|
|
|
|
CP0533372
|
2-chloro-6-fluoro-N-[4-[3-(trifluoromethyl)phenoxy]phenyl]benzamide
Show/Hide
|
C20H12ClF4NO2
|
1
|
| 1 |
IC50 = 2410 nM
|
|
|
|
CP0575189
|
2-chloro-6-[[4-(1,3,4-oxadiazol-2-yl)phenoxy]methyl]benzonitrile
Show/Hide
|
C16H10ClN3O2
|
1
|
| 1 |
IC50 = 2520 nM
|
|
|
|
CP0574225
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]-2-hydroxyphenyl]-2-fluoro-6-iodobenzamide
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C21H11F7INO3
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1
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| 1 |
IC50 = 2630 nM
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CP0533373
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2-chloro-6-fluoro-N-[4-[5-(trifluoromethyl)pyridin-3-yl]oxyphenyl]benzamide
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C19H11ClF4N2O2
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1
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| 1 |
IC50 = 2870 nM
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CP0482367
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluorobenzamide
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C21H12F7NO2
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1
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| 1 |
IC50 = 3000 nM
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CP0534347
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-3-chlorothiophene-2-carboxamide
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C19H10ClF6NO2S
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1
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| 1 |
IC50 = 3200 nM
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CP0493522
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]-2-hydroxyphenyl]-2-chloro-6-fluorobenzamide
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C21H11ClF7NO3
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1
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| 1 |
IC50 = 4020 nM
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CP0482312
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2-chloro-6-fluoro-N-[4-[3-iodo-5-(trifluoromethyl)phenoxy]phenyl]benzamide
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C20H11ClF4INO2
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1
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| 1 |
IC50 = 5000 nM
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CP0552314
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2-chloro-6-[4-(1,3,4-oxadiazol-2-yl)phenoxy]aniline
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C14H10ClN3O2
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1
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| 1 |
IC50 = 5290 nM
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CP0534466
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-bromo-6-fluorobenzamide
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C21H11BrF7NO2
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1
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| 1 |
IC50 = 6000 nM
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CP0438455
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2-(4-phenoxyphenyl)-1,3,4-oxadiazole
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C14H10N2O2
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1
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| 1 |
IC50 = 7260 nM
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CP0379721
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2-[4-[4-[7-(3-morpholin-4-ylpropyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-2-yl]phenyl]piperazin-1-yl]ethanol
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C25H36N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0539158
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2-[4-[2-(4-methoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
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C24H31N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0540174
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2-[4-[2-(3-methoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
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C24H31N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0543451
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2-[4-[2-(6-methoxypyridin-2-yl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
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C23H30N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0482366
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-(trifluoromethoxy)benzamide
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C22H11F10NO3
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1
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| 1 |
IC50 > 50000 nM
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CP0485612
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4-amino-N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluorobenzamide
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C21H13F7N2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0492032
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-4-iodobenzamide
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C21H11F7INO2
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1
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| 1 |
IC50 > 50000 nM
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CP0534958
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N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-4-hydroxybenzamide
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C21H12F7NO3
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1
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| 1 |
IC50 > 50000 nM
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CP0553749
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4-[3,5-bis(trifluoromethyl)phenoxy]-N-[(2-chloro-6-fluorophenyl)methyl]aniline
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C21H13ClF7NO
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1
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| 1 |
IC50 > 50000 nM
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CP0388424
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2-[4-[2-(3,4-dimethoxyphenyl)-3-propan-2-yl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
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C27H37N3O2
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1
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| 1 |
IC50 > 50000 nM
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CP0572227
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N-methyl-2-[4-(3-methyl-2-pyridin-3-yl-1H-indol-5-yl)piperidin-1-yl]ethanamine
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C22H28N4
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1
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| 1 |
IC50 > 3000 nM
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