Brief Information of the Compound and Protein
Compound Name
US10660877, Example 81
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PubChem ID
CID: 134329516
Canonical SMILES
CCc1c([nH]c2c(F)cc(cc12)C1CCNCC1)-c1ccnc(C)c1
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Compound Formula C21H24FN3
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 910 nM
   TI
   LI
   LO
   TS