Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02509 , G-protein coupled bile acid receptor 1
Gene Name GPBAR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q8TDU6
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02509
 
Compound ID Compound Name Compound Formula
CP0390777
4-[[3,5-bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-5H-pyrido[3,2-f][1,4]oxazepin-3-one
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C23H15F7N2O2
 2
1
EC50 = 0.23 nM
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2
EC50 = 19 nM
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CP0532039
[4-[(6-chloro-3-methyl-1-benzofuran-5-yl)oxy]pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C26H22ClN3O3
 1
1
EC50 = 0.28 nM
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CP0452716
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichloro-4-methylphenoxy)pyridin-3-yl]methanone
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C24H21Cl2N3O2
 1
1
EC50 = 0.31 nM
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CP0515670
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-[(3-methyl-1-benzofuran-5-yl)oxy]pyridin-3-yl]methanone
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C26H23N3O3
 1
1
EC50 = 0.45 nM
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CP0479517
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,4,5-trichlorophenoxy)pyridin-3-yl]methanone
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C23H18Cl3N3O2
 1
1
EC50 = 0.46 nM
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CP0487963
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,4,5-trimethylphenoxy)pyridin-3-yl]methanone
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C26H27N3O2
 1
1
EC50 = 0.6 nM
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CP0260244
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dimethylphenoxy)pyridin-3-yl]methanone
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C25H25N3O2
 1
1
EC50 = 0.72 nM
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CP0413820
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichloro-4-ethylphenoxy)pyridin-3-yl]methanone
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C25H23Cl2N3O2
 1
1
EC50 = 0.72 nM
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CP0486477
methyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C27H23N3O5
 1
1
EC50 = 0.9 nM
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CP0389623
[4-[(6-chloro-1-benzofuran-5-yl)oxy]pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C25H20ClN3O3
 1
1
EC50 = 1.4 nM
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CP0441788
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyridin-3-yl]methanone
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C23H19Cl2N3O2
 1
1
EC50 = 1.5 nM
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CP0515671
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-[(3-methyl-1,2-benzoxazol-5-yl)oxy]pyridin-3-yl]methanone
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C25H22N4O3
 1
1
EC50 = 1.5 nM
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CP0400813
ethyl 6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C28H24ClN3O5
 1
1
EC50 = 1.7 nM
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CP0572971
propyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C29H27N3O5
 1
1
EC50 = 2.1 nM
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CP0497864
(4-cyclobutyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyridin-3-yl]methanone
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C24H21Cl2N3O2
 1
1
EC50 = 2.8 nM
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CP0486492
ethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C28H25N3O5
 1
1
EC50 = 2.8 nM
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CP0480775
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]methanone
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C22H18Cl2N4O2
 1
1
EC50 = 2.9 nM
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CP0487939
[4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-ethyl-2,3-dihydroquinoxalin-1-yl)methanone
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C22H19Cl2N3O2
 1
1
EC50 = 3.1 nM
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CP0396809
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(4-methyl-2,3-dihydroquinoxalin-1-yl)methanone
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C20H16Cl2N4O2
 1
1
EC50 = 3.5 nM
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CP0396808
6-(2,5-dichlorophenoxy)-5-(4-methyl-2,3-dihydroquinoxaline-1-carbonyl)-1H-pyrimidin-2-one
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C20H16Cl2N4O3
 1
1
EC50 = 3.9 nM
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CP0568212
methoxymethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C28H25N3O6
 1
1
EC50 = 4.7 nM
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CP0444624
(1R,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bS)-9-(cyclopropylcarbamoyloxy)-1-[(1S)-1-hydroxyethyl]-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C33H53NO5
 1
1
EC50 = 5.07 nM
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CP0554489
N-(2,5-dichlorophenyl)-1-(4-methyl-2,3-dihydroquinoxaline-1-carbonyl)cyclopropane-1-carboxamide
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C20H19Cl2N3O2
 1
1
EC50 = 5.1 nM
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CP0389625
ethyl 2-[6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-yl]acetate
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C29H26ClN3O5
 1
1
EC50 = 5.2 nM
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CP0539752
[2-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-methyl-2,3-dihydroquinoxalin-1-yl)methanone
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C21H17Cl2N3O2
 1
1
EC50 = 6.1 nM
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CP0413818
[4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-prop-2-enyl-2,3-dihydroquinoxalin-1-yl)methanone
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C23H19Cl2N3O2
 1
1
EC50 = 6.2 nM
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CP0527673
methylsulfanylmethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C28H25N3O5S
 1
1
EC50 = 7 nM
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CP0479515
[4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-propyl-2,3-dihydroquinoxalin-1-yl)methanone
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C23H21Cl2N3O2
 1
1
EC50 = 7.1 nM
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CP0453198
[4-[(2-bromo-6-chloro-3-methyl-1-benzofuran-5-yl)oxy]pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C26H21BrClN3O3
 1
1
EC50 = 7.7 nM
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CP0509106
[4-(3-chlorophenoxy)pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C23H20ClN3O2
 1
1
EC50 = 7.9 nM
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CP0453197
ethyl 2-[[(E)-3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-yl]prop-2-enoyl]amino]acetate
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C33H31ClN4O6
 1
1
EC50 = 8.5 nM
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CP0566045
ethyl (E)-3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-yl]prop-2-enoate
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C31H28ClN3O5
 1
1
EC50 = 8.9 nM
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CP0202974
[2-(2,5-dichlorophenoxy)pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
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C21H16Cl2N2O2
 1
1
EC50 = 10 nM
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CP0444622
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C34H55NO4
 1
1
EC50 = 10.06 nM
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CP0400811
[4-(1-benzofuran-5-yloxy)pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C25H21N3O3
 1
1
EC50 = 10.7 nM
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CP0479516
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(4-methylphenoxy)pyridin-3-yl]methanone
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C24H23N3O2
 1
1
EC50 = 12 nM
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CP0497865
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(3-methoxyphenoxy)pyridin-3-yl]methanone
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C24H23N3O3
 1
1
EC50 = 12 nM
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CP0499959
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dimethoxyphenoxy)pyridin-3-yl]methanone
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C25H25N3O4
 1
1
EC50 = 12 nM
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CP0379918
[4-(2,5-dichlorophenoxy)-2-methylsulfanylpyrimidin-5-yl]-(4-methyl-2,3-dihydroquinoxalin-1-yl)methanone
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C21H18Cl2N4O2S
 1
1
EC50 = 12 nM
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CP0471069
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(ethylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C33H55NO4
 1
1
EC50 = 13.04 nM
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CP0471070
(1R,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bS)-1-acetyl-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C33H51NO5
 1
1
EC50 = 13.11 nM
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CP0414624
[4-(1,3-benzothiazol-6-yloxy)pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C24H20N4O2S
 1
1
EC50 = 15 nM
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CP0409987
[4-(1-benzothiophen-5-yloxy)pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C25H21N3O2S
 1
1
EC50 = 16 nM
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CP0486475
ethoxymethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C29H27N3O6
 1
1
EC50 = 16.4 nM
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CP0409997
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-naphthalen-1-yloxypyridin-3-yl)methanone
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C27H23N3O2
 1
1
EC50 = 17 nM
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CP0419154
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-9-(methylcarbamoyloxy)-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C32H53NO4
 1
1
EC50 = 17.81 nM
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CP0453200
[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl] 5-chloro-2-(3-ethoxy-3-oxopropyl)-3-methyl-1-benzofuran-4-carboxylate
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C32H30ClN3O6
 1
1
EC50 = 18 nM
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CP0444614
(1R,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bS)-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-[(2S)-2-methyloxiran-2-yl]-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C34H53NO5
 1
1
EC50 = 18.63 nM
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CP0441787
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(4-ethyl-2,3-dihydroquinoxalin-1-yl)methanone
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C21H18Cl2N4O2
 1
1
EC50 = 20 nM
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CP0555621
6-(2,5-dichloroanilino)-5-(4-methyl-2,3-dihydroquinoxaline-1-carbonyl)-1H-pyrimidin-2-one
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C20H17Cl2N5O2
 1
1
EC50 = 20 nM
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CP0545976
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-fluoro-3-methoxyphenyl)-N-methylimidazol-4-amine
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C26H24F3N3O3S
 1
1
EC50 = 20 nM
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CP0480887
(4-cyclobutyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]methanone
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C23H20Cl2N4O2
 1
1
EC50 = 23 nM
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CP0560548
2,2,2-trifluoroethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
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C28H22F3N3O5
 1
1
EC50 = 23.3 nM
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CP0049016
(4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethyl-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
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C26H44O4
 2
1
EC50 = 23.7 nM
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2
EC50 = 840 nM
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CP0389624
[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl] 6-chloro-3-(3-methoxy-3-oxopropyl)-1-benzofuran-5-carboxylate
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C30H26ClN3O6
 1
1
EC50 = 24 nM
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CP0923306
3-[4-[[5-(3,4-Dimethoxy-N-methyl-anilino)-1-(4-fluorophenyl)-imidazol-2-yl]sulfanylmethyl]-3,5-difluoro-phenoxy]propane-1-sulfonate-ammonium
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C28H31F3N4O6S2
 1
1
EC50 = 24 nM
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CP0400812
(E)-3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-yl]prop-2-enoic acid
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C29H24ClN3O5
 1
1
EC50 = 25 nM
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CP0556198
[4-(1-benzofuran-6-yloxy)pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C25H21N3O3
 1
1
EC50 = 25 nM
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CP0144740
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(4R)-3-[(2,5-dichlorophenyl)methyl]-1,3-thiazolidin-4-yl]methanone
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C22H23Cl2N3OS
 1
1
EC50 = 25.12 nM
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CP0405307
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(4R)-3-[[2,5-dichloro-4-(hydroxymethyl)phenyl]methyl]-1,3-thiazolidin-4-yl]methanone
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C23H25Cl2N3O2S
 1
1
EC50 = 25.12 nM
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CP0405328
5-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]-N-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pentanamide
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C34H46Cl2N4O7S
 1
1
EC50 = 25.12 nM
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CP0534420
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(2-methoxyacetyl)oxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C33H54O5
 1
1
EC50 = 25.25 nM
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CP0534423
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclobutylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
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C35H57NO4
 1
1
EC50 = 26.69 nM
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CP0552709
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-9-(propylcarbamoyloxy)-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C34H57NO4
 1
1
EC50 = 26.88 nM
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CP0451126
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(2-hydroxyacetyl)oxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C32H52O5
 1
1
EC50 = 26.96 nM
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CP0441761
[4-(2-chlorophenoxy)pyridin-3-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C23H20ClN3O2
 1
1
EC50 = 27 nM
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CP0557723
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclopentylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C36H59NO4
 1
1
EC50 = 29.19 nM
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CP0441790
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(4-prop-2-enyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C22H18Cl2N4O2
 1
1
EC50 = 30 nM
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CP0452715
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(4-propyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C22H20Cl2N4O2
 1
1
EC50 = 30 nM
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CP0532040
ethyl 2-[3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-yl]propanoylamino]acetate
   Show/Hide
C33H33ClN4O6
 1
1
EC50 = 30 nM
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CP0444618
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-carbamoyloxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C31H51NO4
 1
1
EC50 = 30.7 nM
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CP0395769
N-[3,5-bis(trifluoromethyl)phenyl]sulfonyl-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]benzamide
   Show/Hide
C27H17F7N2O3S
 1
1
EC50 = 31 nM
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CP0391925
1-[5-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]pentyl]-3-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]urea
   Show/Hide
C32H43Cl2N5O5S
 1
1
EC50 = 31.62 nM
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CP0405326
3-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]propanamide
   Show/Hide
C31H40Cl2N4O7S
 1
1
EC50 = 31.62 nM
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CP0472993
1-[4-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]butyl]-3-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]urea
   Show/Hide
C33H45Cl2N5O7S
 1
1
EC50 = 31.62 nM
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CP0443634
N-[3,5-bis(trifluoromethyl)phenyl]sulfonyl-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]furan-2-carboxamide
   Show/Hide
C25H15F7N2O4S
 1
1
EC50 = 32 nM
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CP0453199
2-[[(E)-3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxycarbonyl-3-methyl-1-benzofuran-2-yl]prop-2-enoyl]amino]acetic acid
   Show/Hide
C32H27ClN4O7
 1
1
EC50 = 34 nM
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CP0390779
2-[3,5-bis(trifluoromethyl)phenyl]-2-[[4-(2-fluorophenyl)pyridin-3-yl]methylamino]acetonitrile
   Show/Hide
C22H14F7N3
 1
1
EC50 = 35 nM
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CP0448854
3-[5-chloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-yl]propanoic acid
   Show/Hide
C29H26ClN3O5
 1
1
EC50 = 35 nM
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CP0475160
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C25H22F3N3O2S
 1
1
EC50 = 35 nM
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CP0520023
3-(3-chloro-4-fluorophenyl)-2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-N-methylimidazol-4-amine
   Show/Hide
C25H21ClF3N3O2S
 1
1
EC50 = 35 nM
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CP0451132
(1R,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bS)-9-(cyclopropylcarbamoyloxy)-1-[(1R)-1-hydroxyethyl]-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C33H53NO5
 1
1
EC50 = 37.99 nM
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CP0532041
ethyl 6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-carboxylate
   Show/Hide
C29H26ClN3O5
 1
1
EC50 = 38 nM
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CP0392468
[(4R)-3-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-1,3-thiazolidin-4-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C23H23ClF3N3OS
 1
1
EC50 = 39.81 nM
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CP0472996
5-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pentanamide
   Show/Hide
C33H44Cl2N4O7S
 1
1
EC50 = 39.81 nM
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CP0433862
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-quinolin-5-yloxypyridin-3-yl)methanone
   Show/Hide
C26H22N4O2
 1
1
EC50 = 40 nM
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CP0433861
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-naphthalen-2-yloxypyridin-3-yl)methanone
   Show/Hide
C27H23N3O2
 1
1
EC50 = 41 nM
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CP0536630
[4-(2,5-dichlorophenoxy)-2-methylsulfanylpyrimidin-5-yl]-(3,4-dihydro-2H-quinoxalin-1-yl)methanone
   Show/Hide
C20H16Cl2N4O2S
 1
1
EC50 = 41 nM
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CP0451127
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-9-(methylsulfamoyloxy)-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C31H53NO5S
 1
1
EC50 = 45.37 nM
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CP0413819
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-phenoxypyridin-3-yl)methanone
   Show/Hide
C23H21N3O2
 1
1
EC50 = 47 nM
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CP0468786
3-(2,4-difluorophenyl)-2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-N-methylimidazol-4-amine
   Show/Hide
C25H21F4N3O2S
 1
1
EC50 = 47 nM
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CP0413823
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C20H15Cl2N3O2
 2
1
EC50 = 48 nM
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2
EC50 = 155 nM
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CP0476907
[4-(2,5-dichlorophenoxy)pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C21H16Cl2N2O2
 1
1
EC50 = 49 nM
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CP0391950
5-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]pentanoic acid
   Show/Hide
C27H31Cl2N3O3S
 1
1
EC50 = 50.12 nM
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CP0471003
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S,4S)-1-[(2,5-dichlorophenyl)methyl]-4-fluoropyrrolidin-2-yl]methanone
   Show/Hide
C23H24Cl2FN3O
 1
1
EC50 = 50.12 nM
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CP0390774
2-[3,5-bis(trifluoromethyl)phenyl]-2-[[4-(2,6-difluorophenyl)pyridin-3-yl]methylamino]acetonitrile
   Show/Hide
C22H13F8N3
 1
1
EC50 = 51 nM
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CP0403773
N-[3,5-bis(trifluoromethyl)phenyl]sulfonyl-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]thiophene-3-carboxamide
   Show/Hide
C25H15F7N2O3S2
 1
1
EC50 = 53 nM
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CP0433863
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-quinolin-7-yloxypyridin-3-yl)methanone
   Show/Hide
C26H22N4O2
 1
1
EC50 = 59 nM
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CP0411580
2-[3,5-bis(trifluoromethyl)phenyl]-2-[(4-phenylpyridin-3-yl)methylamino]acetonitrile
   Show/Hide
C22H15F6N3
 1
1
EC50 = 61 nM
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CP0404068
N-[[4-(2,6-difluorophenyl)pyridin-3-yl]methyl]-3,5-bis(trifluoromethyl)benzenesulfonamide
   Show/Hide
C20H12F8N2O2S
 1
1
EC50 = 62 nM
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CP0443636
N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]-3,5-bis(trifluoromethyl)benzenesulfonamide
   Show/Hide
C20H13F7N2O2S
 1
1
EC50 = 63 nM
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CP0515672
6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-3-methyl-1-benzofuran-2-carboxylic acid
   Show/Hide
C27H22ClN3O5
 1
1
EC50 = 63 nM
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CP0391956
3-[4-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]butyl]-1-methyl-1-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]urea
   Show/Hide
C34H47Cl2N5O7S
 1
1
EC50 = 63.1 nM
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CP0391957
3-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]-N-methyl-N-[(2S,3R,4S,5R)-2,3,4,5,6-pentahydroxyhexyl]propanamide
   Show/Hide
C32H42Cl2N4O7S
 1
1
EC50 = 63.1 nM
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CP0463627
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S,4R)-1-[(2,5-dichlorophenyl)methyl]-4-fluoropyrrolidin-2-yl]methanone
   Show/Hide
C23H24Cl2FN3O
 1
1
EC50 = 63.1 nM
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CP0556199
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-quinolin-6-yloxypyridin-3-yl)methanone
   Show/Hide
C26H22N4O2
 1
1
EC50 = 64 nM
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CP0444617
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(ethylsulfamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C32H55NO5S
 1
1
EC50 = 68.59 nM
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CP0509107
[4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-propan-2-yl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C23H21Cl2N3O2
 1
1
EC50 = 69 nM
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CP0468783
N-(3,4-dimethoxyphenyl)-2-[[4-[3-(dimethylamino)prop-1-ynyl]-2,6-difluorophenyl]methylsulfanyl]-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C30H29F3N4O2S
 1
1
EC50 = 71 nM
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CP0904540
2-[3-[4-[[5-(3,4-Dimethoxy-N-methyl-anilino)-1-(4-fluorophenyl)-imidazol-2-yl]sulfanylmethyl]-3,5-difluoro-phenoxy]propyl-(2-sulfonatoethyl)amino]ethanesulfonate-diammonium
   Show/Hide
C32H43F3N6O9S3
 1
1
EC50 = 77 nM
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CP0547911
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-9-propylsulfonyloxy-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C33H56O5S
 1
1
EC50 = 77.63 nM
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CP0448855
[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl] 6-chloro-2-[(2-ethoxy-2-oxoethyl)carbamoyl]-3-methyl-1-benzofuran-5-carboxylate
   Show/Hide
C32H29ClN4O7
 1
1
EC50 = 78 nM
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CP0435307
3-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]-N-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]propanamide
   Show/Hide
C32H42Cl2N4O7S
 1
1
EC50 = 79.43 nM
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CP0435309
2-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methylsulfanyl]-3-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]imidazole-4-carboxamide
   Show/Hide
C34H42Cl2N6O7S2
 1
1
EC50 = 79.43 nM
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CP0472997
1-[5-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]pentyl]-3-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]urea
   Show/Hide
C34H47Cl2N5O7S
 1
1
EC50 = 79.43 nM
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CP0533772
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-ethoxycarbonyloxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C33H54O5
 1
1
EC50 = 80.04 nM
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CP0486493
2-methoxyethoxymethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
   Show/Hide
C30H29N3O7
 1
1
EC50 = 81.5 nM
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CP0444625
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-butanoyloxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C34H56O4
 1
1
EC50 = 83.12 nM
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CP0534667
chloromethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
   Show/Hide
C27H22ClN3O5
 1
1
EC50 = 83.7 nM
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CP0559261
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-N-prop-2-enylimidazol-4-amine
   Show/Hide
C27H24F3N3O2S
 1
1
EC50 = 86 nM
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CP0191847
6alpha-ethyl-23(S)-methyl-cholic acid
   Show/Hide
C27H46O5
 4
1
EC50 = 95.8 nM
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2
EC50 = 293 nM
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3
EC50 = 1004 nM
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4
EC50 = 1230 nM
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CP0387113
1-[4-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenoxy]butyl]-3-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]urea
   Show/Hide
C33H45Cl2N5O8S
 1
1
EC50 = 100 nM
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CP0392465
6-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methoxy]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pyridine-3-carboxamide
   Show/Hide
C35H41Cl2N5O8S
 1
1
EC50 = 100 nM
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CP0392466
1-[4-[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]butyl]-3-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]urea
   Show/Hide
C31H41Cl2N5O5S
 1
1
EC50 = 100 nM
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CP0405327
5-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methoxy]-1-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pyrazole-3-carboxamide
   Show/Hide
C34H42Cl2N6O8S
 1
1
EC50 = 100 nM
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CP0435314
1-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pyrazole-3-carboxamide
   Show/Hide
C33H40Cl2N6O7S
 1
1
EC50 = 100 nM
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CP0463626
6-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenoxy]methyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pyridine-3-carboxamide
   Show/Hide
C35H41Cl2N5O8S
 1
1
EC50 = 100 nM
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CP0471002
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(4R)-3-[(2,5-dichloro-4-hydroxyphenyl)methyl]-1,3-thiazolidin-4-yl]methanone
   Show/Hide
C22H23Cl2N3O2S
 1
1
EC50 = 100 nM
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CP0549116
(2S,4R)-4-[(3R,5R,6R,7R,8S,9S,10S,12S,13R,14R,17R)-6-ethyl-3,7,12-trihydroxy-10-methyl-1,2,3,4,5,6,7,8,9,11,12,13,14,15,16,17-hexadecahydrocyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
   Show/Hide
C26H44O5
 1
1
EC50 = 116.6 nM
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CP0542196
ethyl 2-[3-[6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-yl]propanoylamino]acetate
   Show/Hide
C32H31ClN4O6
 1
1
EC50 = 119 nM
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CP0375371
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]thiophene-3-carboxamide
   Show/Hide
C26H18F6N2OS
 1
1
EC50 = 120 nM
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CP0414222
1-(4-methyl-2,3-dihydroquinoxaline-1-carbonyl)-N-(2,4,5-trifluorophenyl)cyclopropane-1-carboxamide
   Show/Hide
C20H18F3N3O2
 1
1
EC50 = 122 nM
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CP0555749
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-9-(propan-2-ylcarbamoyloxy)-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C34H57NO4
 1
1
EC50 = 123.9 nM
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CP0387106
[(4R)-3-[(2-chloro-5-iodophenyl)methyl]-1,3-thiazolidin-4-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C22H23ClIN3OS
 1
1
EC50 = 125.89 nM
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CP0405306
3-[2,5-dichloro-4-[[(2S)-2-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyrrolidin-1-yl]methyl]phenyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]propanamide
   Show/Hide
C32H42Cl2N4O7
 1
1
EC50 = 125.89 nM
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CP0438398
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S)-1-[(2,5-dichlorophenyl)methyl]-4,4-difluoropyrrolidin-2-yl]methanone
   Show/Hide
C23H23Cl2F2N3O
 1
1
EC50 = 125.89 nM
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CP0472992
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S,4R)-1-[(2,5-dichlorophenyl)methyl]-4-methoxypyrrolidin-2-yl]methanone
   Show/Hide
C24H27Cl2N3O2
 1
1
EC50 = 125.89 nM
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CP0479513
[4-(2,5-dichlorophenoxy)pyridin-3-yl]-(2,3-dihydro-1,4-benzoxazin-4-yl)methanone
   Show/Hide
C20H14Cl2N2O3
 1
1
EC50 = 127 nM
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CP0463356
N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-2-[(2-fluorophenyl)methylsulfanyl]-N-methylimidazol-4-amine
   Show/Hide
C25H23F2N3O2S
 1
1
EC50 = 128 nM
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CP0444616
(1R,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bS)-9-(cyclopropylcarbamoyloxy)-1-[(Z)-N-methoxy-C-methylcarbonimidoyl]-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C34H54N2O5
 1
1
EC50 = 131.6 nM
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CP0545857
ethoxycarbonyloxymethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
   Show/Hide
C30H27N3O8
 1
1
EC50 = 137 nM
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CP0549475
acetyloxymethyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
   Show/Hide
C29H25N3O7
 1
1
EC50 = 145 nM
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CP0433864
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(1H-indol-4-yloxy)pyridin-3-yl]methanone
   Show/Hide
C25H22N4O2
 1
1
EC50 = 148 nM
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CP0475158
2-benzylsulfanyl-N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C25H24FN3O2S
 1
1
EC50 = 156 nM
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CP0387109
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S,4R)-1-[(2,5-dichlorophenyl)methyl]-4-hydroxypyrrolidin-2-yl]methanone
   Show/Hide
C23H25Cl2N3O2
 1
1
EC50 = 158.49 nM
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CP0544393
4-(2,5-dichlorophenoxy)-N-(2-methoxyphenyl)-N-methylpyrimidine-5-carboxamide
   Show/Hide
C19H15Cl2N3O3
 1
1
EC50 = 160 nM
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CP0403244
(3S)-N-[(3R)-3-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]-3-hydroxypyrrolidine-1-carboxamide
   Show/Hide
C30H52N2O4
 1
1
EC50 = 160 nM
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CP0536760
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(1H-indol-6-yloxy)pyridin-3-yl]methanone
   Show/Hide
C25H22N4O2
 1
1
EC50 = 162 nM
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CP0497863
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(2,3-dihydro-1,4-benzothiazin-4-yl)methanone
   Show/Hide
C19H13Cl2N3O2S
 1
1
EC50 = 164 nM
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CP0549115
2-[[(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-3a-yl]carbamoylamino]acetic acid
   Show/Hide
C36H59N3O5
 1
1
EC50 = 173.7 nM
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CP0944562
(1S,3aS,5aR,5bR,9R,11aR)-9-(((1H-Pyrazol-3-yl)carbamoyl)oxy)-1-isopropyl-5a,5b,8,8,11a-pentamethylicosahydro-3aHcyclopenta[a]chrysene-3a-carboxylic Acid
   Show/Hide
C34H53N3O4
 1
1
EC50 = 174.9 nM
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CP0901431
(3-{4-[5-[(3,4-Dimethoxy-phenyl)-methylamino]-1-(4-fluoro-phenyl)-1H-imidazol-2-ylsulfanylmethyl]-3,5-difluoro-phenyl}-prop-2-ynyl)-trimethylammonium iodide
   Show/Hide
C31H32F3IN4O2S
 1
1
EC50 = 177 nM
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CP0461332
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-(4-quinolin-8-yloxypyridin-3-yl)methanone
   Show/Hide
C26H22N4O2
 1
1
EC50 = 178 nM
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CP0379868
N-(2,5-dichlorophenyl)-1-(3,4-dihydro-2H-quinoxaline-1-carbonyl)cyclopropane-1-carboxamide
   Show/Hide
C19H17Cl2N3O2
 1
1
EC50 = 178 nM
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CP0391953
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S)-1-[(2,5-dichlorophenyl)methyl]pyrrolidin-2-yl]methanone
   Show/Hide
C23H25Cl2N3O
 1
1
EC50 = 199.53 nM
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CP0405323
4-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methoxy]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]benzamide
   Show/Hide
C36H42Cl2N4O8S
 1
1
EC50 = 199.53 nM
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CP0438401
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S,4S)-1-[(2,5-dichlorophenyl)methyl]-4-methoxypyrrolidin-2-yl]methanone
   Show/Hide
C24H27Cl2N3O2
 1
1
EC50 = 199.53 nM
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CP0471007
[(4R)-3-[[4-(5-aminopentyl)-2,5-dichlorophenyl]methyl]-1,3-thiazolidin-4-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C27H34Cl2N4OS
 1
1
EC50 = 199.53 nM
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CP0520855
5-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methoxy]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]pyridine-2-carboxamide
   Show/Hide
C35H41Cl2N5O8S
 1
1
EC50 = 199.53 nM
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CP0411579
1-[3,5-bis(trifluoromethyl)phenyl]-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]ethanamine
   Show/Hide
C22H17F7N2
 1
1
EC50 = 204 nM
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CP0547222
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-[ethyl(methyl)carbamoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C34H57NO4
 1
1
EC50 = 211.2 nM
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CP0449161
(2S,4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
   Show/Hide
C25H42O3
 1
1
EC50 = 220 nM
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CP0534424
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-[(4-methoxyphenyl)carbamoyloxy]-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C38H57NO5
 1
1
EC50 = 229.9 nM
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CP0901429
2-[[4-[3-(1-Aza-4-azoniabicyclo[2.2.2]octan-4-yl)propoxy]-2,6-difluoro-phenyl]methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-N-methyl-imidazol-4-amine-formate
   Show/Hide
C35H40F3N5O5S
 1
1
EC50 = 238 nM
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CP0400814
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-[(3-methyl-1,2-benzoxazol-6-yl)oxy]pyridin-3-yl]methanone
   Show/Hide
C25H22N4O3
 1
1
EC50 = 240 nM
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CP0384776
[(3S)-oxolan-3-yl] N-[(3R)-3-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]carbamate
   Show/Hide
C30H51NO5
 1
1
EC50 = 240 nM
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CP0511859
2-[[(3R)-3-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]amino]-2-oxoacetic acid
   Show/Hide
C27H45NO5
 1
1
EC50 = 240 nM
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CP0387107
5-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenoxy]methyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]furan-2-carboxamide
   Show/Hide
C34H40Cl2N4O9S
 1
1
EC50 = 251.19 nM
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CP0405314
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(4R)-3-[(2,5-dichlorophenyl)methyl]-2,2-dimethyl-1,3-thiazolidin-4-yl]methanone
   Show/Hide
C24H27Cl2N3OS
 1
1
EC50 = 251.19 nM
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CP0438404
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(3S)-4-[(2,5-dichlorophenyl)methyl]morpholin-3-yl]methanone
   Show/Hide
C23H25Cl2N3O2
 1
1
EC50 = 251.19 nM
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CP0463629
3-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methoxy]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]benzamide
   Show/Hide
C36H42Cl2N4O8S
 1
1
EC50 = 251.19 nM
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CP0539987
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-N-methyl-3-phenylimidazol-4-amine
   Show/Hide
C25H23F2N3O2S
 1
1
EC50 = 254 nM
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CP0413817
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]thiophene-2-carboxamide
   Show/Hide
C26H18F6N2OS
 1
1
EC50 = 260 nM
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CP0923307
(3-{4-[5-[(3,4-Dimethoxy-phenyl)-methylamino]-1-(4-fluoro-phenyl)-1H-imidazol-2-ylsulfanylmethyl]-3,5-difluoro-phenyl}-prop-2-ynyl)-trimethylammonium formate
   Show/Hide
C32H33F3N4O4S
 1
1
EC50 = 260 nM
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CP0547226
2-[[(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-3a-yl]carbamoyloxy]acetic acid
   Show/Hide
C36H58N2O6
 1
1
EC50 = 270.8 nM
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CP0431746
ethyl N-[(3R)-3-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]carbamate
   Show/Hide
C28H49NO4
 1
1
EC50 = 280 nM
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CP0474941
N-(3,4-dimethoxyphenyl)-2-[(2,6-dimethylphenyl)methylsulfanyl]-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C27H28FN3O2S
 1
1
EC50 = 299 nM
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CP0444620
2-[(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]oxyacetic acid
   Show/Hide
C36H57NO6
 1
1
EC50 = 306.4 nM
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CP0390773
N-[1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-N-[(4-phenylpyridin-3-yl)methyl]furan-2-carboxamide
   Show/Hide
C27H20F6N2O2
 1
1
EC50 = 310 nM
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CP0405318
2-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]methylsulfanyl]-3-methylimidazole-4-carboxylic acid
   Show/Hide
C28H29Cl2N5O3S2
 1
1
EC50 = 316.23 nM
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CP0463628
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(3R)-4-[(2,5-dichlorophenyl)methyl]thiomorpholin-3-yl]methanone
   Show/Hide
C23H25Cl2N3OS
 1
1
EC50 = 316.23 nM
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CP0443617
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]furan-3-carboxamide
   Show/Hide
C26H18F6N2O2
 1
1
EC50 = 320 nM
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   TS
CP0515608
2-[(2,6-difluorophenyl)methylsulfanyl]-N-[(3,4-dimethoxyphenyl)methyl]-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C26H24F3N3O2S
 1
1
EC50 = 326 nM
   TI
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   TS
CP0463357
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-N,5-dimethylimidazol-4-amine
   Show/Hide
C26H24F3N3O2S
 1
1
EC50 = 337 nM
   TI
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CP0379611
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]benzamide
   Show/Hide
C28H20F6N2O
 1
1
EC50 = 350 nM
   TI
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CP0547224
2-[[(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-(cyclopropylcarbamoyloxy)-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]amino]acetic acid
   Show/Hide
C36H58N2O5
 1
1
EC50 = 380.1 nM
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CP0411582
1-[3,5-bis(trifluoromethyl)phenyl]-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]propan-1-amine
   Show/Hide
C23H19F7N2
 1
1
EC50 = 384 nM
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CP0405320
3-[2,5-dichloro-4-[[(2S,4S)-2-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-4-fluoropyrrolidin-1-yl]methyl]phenyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]propanamide
   Show/Hide
C32H41Cl2FN4O7
 1
1
EC50 = 398.11 nM
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CP0513250
4-[[2,5-dichloro-4-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenoxy]methyl]benzoic acid
   Show/Hide
C30H29Cl2N3O4S
 1
1
EC50 = 398.11 nM
   TI
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CP0515192
N-[[2-chloro-4-(2-fluorophenyl)pyridin-3-yl]methyl]-3,5-bis(trifluoromethyl)benzenesulfonamide
   Show/Hide
C20H12ClF7N2O2S
 1
1
EC50 = 406 nM
   TI
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CP0511838
1-cyclopropyl-3-[(3R)-3-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]urea
   Show/Hide
C29H50N2O3
 1
1
EC50 = 420 nM
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CP0390772
methyl 2-[3,5-bis(trifluoromethyl)phenyl]-2-[[4-(2-fluorophenyl)pyridin-3-yl]methylamino]acetate
   Show/Hide
C23H17F7N2O2
 1
1
EC50 = 440 nM
   TI
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CP0488600
N-(2-chlorophenyl)-4-(2,5-dichlorophenoxy)-N-methylpyridine-3-carboxamide
   Show/Hide
C19H13Cl3N2O2
 1
1
EC50 = 451 nM
   TI
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CP0534421
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-9-(morpholine-4-carbonyloxy)-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C35H57NO5
 1
1
EC50 = 452.3 nM
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CP0525279
1-[3,5-bis(trifluoromethyl)phenyl]-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]methanamine
   Show/Hide
C21H15F7N2
 1
1
EC50 = 458 nM
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CP0390778
2-[3,5-bis(trifluoromethyl)phenyl]-2-[[4-(2-fluorophenyl)pyridin-3-yl]methyl-propylamino]acetonitrile
   Show/Hide
C25H20F7N3
 1
1
EC50 = 466 nM
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CP0403770
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]furan-2-carboxamide
   Show/Hide
C26H18F6N2O2
 1
1
EC50 = 470 nM
   TI
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   TS
CP0474894
3-[(2,6-difluorophenyl)methylsulfanyl]-5-[(3,4-dimethoxyphenyl)methyl]-4-(4-fluorophenyl)-1,2,4-triazole
   Show/Hide
C24H20F3N3O2S
 1
1
EC50 = 470 nM
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CP0515191
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]furan-2-carboxamide
   Show/Hide
C26H17F7N2O2
 1
1
EC50 = 500 nM
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CP0438397
[(4R)-3-[(2-chloro-5-cyclopropylphenyl)methyl]-1,3-thiazolidin-4-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C25H28ClN3OS
 1
1
EC50 = 501.19 nM
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CP0461331
[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl] 6-chloro-3-[2-[(2-ethoxy-2-oxoethyl)amino]-2-oxoethyl]-1-benzofuran-5-carboxylate
   Show/Hide
C32H29ClN4O7
 1
1
EC50 = 520 nM
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CP0403243
5-[(3R)-3-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]-1,2-oxazol-3-one
   Show/Hide
C28H45NO4
 1
1
EC50 = 520 nM
   TI
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CP0544392
4-(2,5-dichlorophenoxy)-N-methyl-N-(2-methylphenyl)pyrimidine-5-carboxamide
   Show/Hide
C19H15Cl2N3O2
 1
1
EC50 = 535 nM
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CP0389169
1-[3,5-bis(trifluoromethyl)phenyl]-N-[(4-phenylpyridin-3-yl)methyl]methanamine
   Show/Hide
C21H16F6N2
 1
1
EC50 = 580 nM
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CP0508496
(2S,4R)-4-[(3R,5S,6S,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
   Show/Hide
C27H46O3
 1
1
EC50 = 580 nM
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CP0413821
(4-butyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]methanone
   Show/Hide
C23H22Cl2N4O2
 1
1
EC50 = 590 nM
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CP0410000
3-[6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-yl]propanoic acid
   Show/Hide
C28H24ClN3O5
 1
1
EC50 = 675 nM
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CP0068212
(3alpha,5beta)-3-hydroxycholan-24-oic acid
   Show/Hide
C24H40O3
 1
1
EC50 = 680 nM
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CP0475680
(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methylsulfonylpentanamide
   Show/Hide
C27H47NO5S
 1
1
EC50 = 700 nM
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CP0499972
[4-(2,5-dichlorophenoxy)pyrimidin-5-yl]-(4-propan-2-yl-2,3-dihydroquinoxalin-1-yl)methanone
   Show/Hide
C22H20Cl2N4O2
 1
1
EC50 = 710 nM
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CP0400258
(2S,4R)-4-[(3R,5S,6R,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
   Show/Hide
C27H46O4
 1
1
EC50 = 730 nM
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CP0511192
(4R)-4-[(3R,5S,6S,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
   Show/Hide
C26H44O3
 1
1
EC50 = 750 nM
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CP0516892
N-(3,4-dichlorophenyl)-2-[(2,6-difluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C23H16Cl2F3N3S
 1
1
EC50 = 750 nM
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CP0391958
3-[4-chloro-3-[[(4R)-4-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)-1,3-thiazolidin-3-yl]methyl]phenyl]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]propanamide
   Show/Hide
C31H41ClN4O7S
 1
1
EC50 = 794.33 nM
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CP0471004
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S,4S)-1-[(2,5-dichlorophenyl)methyl]-4-hydroxypyrrolidin-2-yl]methanone
   Show/Hide
C23H25Cl2N3O2
 1
1
EC50 = 794.33 nM
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CP0475198
(2S)-N-(2-cyclobutyloxyphenyl)-1-[(2,5-dichlorophenyl)methyl]-N-methylpyrrolidine-2-carboxamide
   Show/Hide
C23H26Cl2N2O2
 1
1
EC50 = 794.33 nM
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CP0533773
[(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-3a-amino-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-yl] N-cyclopropylcarbamate
   Show/Hide
C33H56N2O2
 1
1
EC50 = 867.1 nM
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CP0548317
N-(4-chloro-3-methoxyphenyl)-2-[(2,6-difluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C24H19ClF3N3OS
 1
1
EC50 = 885 nM
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CP0444184
2-[3,5-bis(trifluoromethyl)phenyl]-2-[[4-(2-fluorophenyl)pyridin-3-yl]methyl-(furan-2-ylmethyl)amino]acetonitrile
   Show/Hide
C27H18F7N3O
 1
1
EC50 = 892 nM
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CP0512855
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-N-methyl-3-[4-(trifluoromethyl)phenyl]imidazol-4-amine
   Show/Hide
C26H22F5N3O2S
 1
1
EC50 = 900 nM
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CP0487814
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]acetamide
   Show/Hide
C23H18F6N2O
 1
1
EC50 = 910 nM
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CP0563298
2-[(2,6-difluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)-N-(3-methoxyphenyl)-N-methylimidazol-4-amine
   Show/Hide
C24H20F3N3OS
 1
1
EC50 = 994 nM
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CP0391926
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S)-1-[(2,5-dichlorophenyl)methyl]azetidin-2-yl]methanone
   Show/Hide
C22H23Cl2N3O
 1
1
EC50 = 1000 nM
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CP0471005
(2S)-N-(2-cyclopropyloxyphenyl)-1-[(2,5-dichlorophenyl)methyl]-N-methylpyrrolidine-2-carboxamide
   Show/Hide
C22H24Cl2N2O2
 1
1
EC50 = 1000 nM
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CP0543366
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S)-1-[(2,5-dichlorophenyl)methyl]-2-methylpyrrolidin-2-yl]methanone
   Show/Hide
C24H27Cl2N3O
 1
1
EC50 = 1000 nM
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CP0400259
(2S,4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
   Show/Hide
C25H42O4
 1
1
EC50 = 1050 nM
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CP0540506
2-[(2,6-difluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)-N-(4-methoxyphenyl)-N-methylimidazol-4-amine
   Show/Hide
C24H20F3N3OS
 1
1
EC50 = 1106 nM
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CP0460507
methyl 3-[2-[(2,6-difluorophenyl)methylsulfanyl]-5-(3,4-dimethoxy-N-methylanilino)-1-(4-fluorophenyl)imidazol-4-yl]propanoate
   Show/Hide
C29H28F3N3O4S
 1
1
EC50 = 1113 nM
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CP0400815
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(1H-indol-5-yloxy)pyridin-3-yl]methanone
   Show/Hide
C25H22N4O2
 1
1
EC50 = 1216 nM
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CP0389207
N-[1-[3,5-bis(trifluoromethyl)phenyl]propyl]-N-[(4-phenylpyridin-3-yl)methyl]furan-2-carboxamide
   Show/Hide
C28H22F6N2O2
 1
1
EC50 = 1230 nM
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CP0525278
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]propanamide
   Show/Hide
C24H20F6N2O
 1
1
EC50 = 1270 nM
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CP0486476
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylate
   Show/Hide
C31H25N3O8
 1
1
EC50 = 1287 nM
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CP0474895
4-ethyl-1-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-[1,2,4]triazolo[4,3-a]quinazolin-5-one
   Show/Hide
C19H15F3N4OS
 1
1
EC50 = 1310 nM
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CP0515675
2-[6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-yl]acetic acid
   Show/Hide
C27H22ClN3O5
 1
1
EC50 = 1358 nM
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   TS
CP0566046
[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl] 6-chloro-3-[(2-ethoxy-2-oxoethyl)carbamoyl]-1-benzofuran-5-carboxylate
   Show/Hide
C31H27ClN4O7
 1
1
EC50 = 1405 nM
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CP0354273
(4R)-4-[(3R,5S,6R,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
   Show/Hide
C26H44O4
 1
1
EC50 = 1490 nM
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CP0177105
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid
   Show/Hide
C28H27Cl2N3O4
 1
1
EC50 = 1497 nM
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CP0444619
(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-[(4-fluorophenyl)carbamoyloxy]-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
   Show/Hide
C37H54FNO4
 1
1
EC50 = 1506 nM
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CP0460760
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2S)-1-[(2,5-dichlorophenyl)methyl]piperidin-2-yl]methanone
   Show/Hide
C24H27Cl2N3O
 1
1
EC50 = 1584.89 nM
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CP0400816
6-chloro-5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylic acid
   Show/Hide
C26H20ClN3O5
 1
1
EC50 = 1673 nM
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CP0384775
(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-10,13-dimethyl-17-[(2R)-4-(2H-tetrazol-5-yl)butan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
   Show/Hide
C26H44N4O2
 1
1
EC50 = 1770 nM
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CP0438405
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2R)-1-[(2,5-dichlorophenyl)methyl]piperidin-2-yl]methanone
   Show/Hide
C24H27Cl2N3O
 1
1
EC50 = 1995.26 nM
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CP0443637
N-benzyl-N-[[4-(2-fluorophenyl)pyridin-3-yl]methyl]-3,5-bis(trifluoromethyl)benzenesulfonamide
   Show/Hide
C27H19F7N2O2S
 1
1
EC50 = 2100 nM
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CP0072113
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7-bis(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
   Show/Hide
C24H40O4
 1
1
EC50 = 2390 nM
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CP0513248
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[(2R)-1-[(2,5-dichlorophenyl)methyl]pyrrolidin-2-yl]methanone
   Show/Hide
C23H25Cl2N3O
 1
1
EC50 = 2511.89 nM
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CP0487680
5-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxy-1-benzofuran-3-carboxylic acid
   Show/Hide
C26H21N3O5
 1
1
EC50 = 2577 nM
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   TS
CP0400257
(2S,4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2-methylpentanoic acid
   Show/Hide
C25H42O4
 1
1
EC50 = 2830 nM
   TI
   LI
   LO
   TS
CP0556926
4-(2,5-dichlorophenoxy)-N-methyl-N-phenylpyrimidine-5-carboxamide
   Show/Hide
C18H13Cl2N3O2
 1
1
EC50 = 3151 nM
   TI
   LI
   LO
   TS
CP0487938
4-(2,5-dichlorophenoxy)-N-[2-(dimethylamino)phenyl]-N-methylpyrimidine-5-carboxamide
   Show/Hide
C20H18Cl2N4O2
 1
1
EC50 = 3711 nM
   TI
   LI
   LO
   TS
CP0441233
ethyl 3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoate
   Show/Hide
C28H27Cl2N3O4
 1
1
EC50 = 3800 nM
   TI
   LI
   LO
   TS
CP0481687
[5-(2,5-dichlorophenoxy)pyrimidin-4-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C20H15Cl2N3O2
 1
1
EC50 = 3871 nM
   TI
   LI
   LO
   TS
CP0435311
[(2S)-1-[(2,5-dichlorophenyl)methyl]pyrrolidin-2-yl]-(2,3-dihydro-1,4-benzothiazin-4-yl)methanone
   Show/Hide
C20H20Cl2N2OS
 1
1
EC50 = 3981.07 nM
   TI
   LI
   LO
   TS
CP0443618
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]pyridine-4-carboxamide
   Show/Hide
C27H19F6N3O
 1
1
EC50 = 4080 nM
   TI
   LI
   LO
   TS
CP0548318
5-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-4-(4-fluorophenyl)-N-methyl-1,2,4-triazol-3-amine
   Show/Hide
C24H21F3N4O2S
 1
1
EC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0479512
4-(2,5-dichlorophenoxy)-N-ethyl-N-(2-methylphenyl)pyrimidine-5-carboxamide
   Show/Hide
C20H17Cl2N3O2
 1
1
EC50 = 4886 nM
   TI
   LI
   LO
   TS
CP0410853
ethyl 2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoyl-methylamino]acetate
   Show/Hide
C31H32Cl2N4O5
 1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0519722
ethyl 2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]acetate
   Show/Hide
C30H30Cl2N4O5
 1
1
EC50 = 5300 nM
   TI
   LI
   LO
   TS
CP0556925
[3-(2,5-dichlorophenoxy)pyrazin-2-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C20H15Cl2N3O2
 1
1
EC50 = 5422 nM
   TI
   LI
   LO
   TS
CP0002372
(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
   Show/Hide
C24H40O4
 1
1
EC50 = 6100 nM
   TI
   LI
   LO
   TS
CP0487840
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-chloro-N-[(4-phenylpyridin-3-yl)methyl]benzamide
   Show/Hide
C28H19ClF6N2O
 1
1
EC50 = 7430 nM
   TI
   LI
   LO
   TS
CP0515607
2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-N-methylimidazol-4-amine
   Show/Hide
C26H25F2N3O3S
 1
1
EC50 = 7745 nM
   TI
   LI
   LO
   TS
CP0435308
[(2S)-1-[(2,5-dichlorophenyl)methyl]pyrrolidin-2-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C21H22Cl2N2O
 1
1
EC50 = 7943.28 nM
   TI
   LI
   LO
   TS
CP0519723
3-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]propanoic acid
   Show/Hide
C29H28Cl2N4O5
 1
1
EC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0381978
(2S,4R)-4-[(5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7-dioxo-2,4,5,6,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
   Show/Hide
C25H38O4
 1
1
EC50 = 9130 nM
   TI
   LI
   LO
   TS
CP0519721
2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]acetic acid
   Show/Hide
C28H26Cl2N4O5
 1
1
EC50 = 9600 nM
   TI
   LI
   LO
   TS
CP0476906
[3-(2,5-dichlorophenoxy)pyridin-2-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C21H16Cl2N2O2
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0499947
4-(2,5-dichlorophenoxy)-N-(2-methylphenyl)pyrimidine-5-carboxamide
   Show/Hide
C18H13Cl2N3O2
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0544869
5-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-4-(4-fluorophenyl)-1,2,4-triazol-3-amine
   Show/Hide
C23H19F3N4O2S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0952636
4-[2-[(2,6-Difluorophenyl)methylsulfanyl]-5-(3,4-dimethoxy-N-methyl-anilino)-1-(4-fluorophenyl)imidazol-4-yl]butyl-trimethylammonium-formate
   Show/Hide
C33H39F3N4O4S
 1
1
EC50 >= 10000 nM
   TI
   LI
   LO
   TS
CP0391951
(2S)-N-[2-(cyclopropylmethoxy)phenyl]-1-[(2,5-dichlorophenyl)methyl]-N-methylpyrrolidine-2-carboxamide
   Show/Hide
C23H26Cl2N2O2
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0391952
[(2S)-1-[(2,5-dichlorophenyl)methyl]pyrrolidin-2-yl]-(4-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C22H24Cl2N2O
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0480382
3,7-diketone
   Show/Hide
C24H36O4
 1
1
EC50 = 10930 nM
   TI
   LI
   LO
   TS
CP0415204
ethyl 3-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]propanoate
   Show/Hide
C31H32Cl2N4O5
 1
1
EC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0441232
2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoyl-methylamino]acetic acid
   Show/Hide
C29H28Cl2N4O5
 1
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0499289
3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]-N-[2-[2-[2-[2-[2-[2-[2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C66H74Cl4N8O12
 1
1
EC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0441231
3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]-N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C70H82Cl4N8O14
 1
1
EC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0415203
3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]-N-[2-[2-[2-[2-[3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C60H62Cl4N8O9
 1
1
EC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0415205
3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoic acid
   Show/Hide
C26H23Cl2N3O4
 1
1
EC50 = 35000 nM
   TI
   LI
   LO
   TS
CP0177108
2-[3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxymethyl]-3-fluoro-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
   Show/Hide
C30H26F5N3O5S
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0534085
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxymethyl]-4-fluoropiperidin-1-yl]-1-methylindole-3-carboxylic acid
   Show/Hide
C29H28Cl2FN3O4
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0508093
[4-(2,5-dichloroanilino)pyrimidin-5-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
C20H16Cl2N4O
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0545795
N-(2,5-dichlorophenyl)-1-(3,4-dihydro-2H-quinoline-1-carbonyl)-N-methylcyclopropane-1-carboxamide
   Show/Hide
C21H20Cl2N2O2
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0550825
N-(2-aminophenyl)-4-(2,5-dichlorophenoxy)-N-methylpyrimidine-5-carboxamide
   Show/Hide
C18H14Cl2N4O2
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0523564
5-(4-aminobutyl)-2-[(2,6-difluorophenyl)methylsulfanyl]-N-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-N-methylimidazol-4-amine
   Show/Hide
C29H31F3N4O2S
 1
1
EC50 > 4500 nM
   TI
   LI
   LO
   TS
CP0435365
2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-4-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C24H22BrN3O
 1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
CP0386163
2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2OS
 1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS
CP0487914
2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C24H22BrN3O
 1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS
CP0506215
3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl)quinolin-6-ol
   Show/Hide
C22H19BrN2OS
 1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
CP0487913
2-(4-chlorophenyl)-N-((7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21ClN2OS
 1
1
IC50 = 97 nM
   TI
   LI
   LO
   TS
CP0507508
(2S,4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethyl-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2-methylpentanoic acid
   Show/Hide
C27H46O4
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0374154
3-((4-bromophenethylamino)methyl)-7-methoxy-2-(thiophen-3-yl)quinolin-6-ol
   Show/Hide
C23H21BrN2O2S
 1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
CP0388572
2-(4-bromophenyl)-N-((7-methoxy-2-phenylquinolin-3-yl)methyl)ethanamine
   Show/Hide
C25H23BrN2O
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0478818
2-(4-bromophenyl)-N-((2-(furan-2-yl)-7-methoxyquinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2O2
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0435363
1-(4-chlorophenyl)-N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]methanamine
   Show/Hide
C22H19ClN2OS
 1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CP0470471
2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-2-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2OS
 1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CP0470472
2-(4-bromophenyl)-N-((2-(furan-3-yl)-7-methoxyquinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2O2
 1
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
CP0388571
1-(7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)-N-(4-methylbenzyl)methanamine
   Show/Hide
C23H22N2OS
 1
1
IC50 = 880 nM
   TI
   LI
   LO
   TS
CP0377218
1-(7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)-N-(4-methoxybenzyl)methanamine
   Show/Hide
C23H22N2O2S
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0377251
2-(4-bromophenyl)-N-((7-methoxy-2-(oxazol-2-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C22H20BrN3O2
 1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0502960
2-(3-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2OS
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0388573
2-(4-bromophenyl)-N-((7-ethoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C24H23BrN2OS
 1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0469328
2-(4-bromophenyl)-N-((7-methyl-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2S
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0502951
2-(4-bromophenyl)-N-((7-methoxy-2-(thiazol-2-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C22H20BrN3OS
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0509585
3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl)quinolin-7-ol
   Show/Hide
C22H19BrN2OS
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0470473
2-(4-bromophenyl)-N-((2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C22H19BrN2S
 1
1
IC50 = 5500 nM
   TI
   LI
   LO
   TS
CP0057055
(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
   Show/Hide
C24H40O5
 1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0472803
2-(4-bromophenyl)-N-((7-chloro-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C22H18BrClN2S
 1
1
IC50 = 6900 nM
   TI
   LI
   LO
   TS
CP0377220
3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl)quinoline-6,7-diol
   Show/Hide
C22H19BrN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0435368
2-(4-bromophenyl)-N-((6-methoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H21BrN2OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0472805
3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl)quinoline-7-carboxylic acid
   Show/Hide
C23H19BrN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0478821
3-((4-bromophenethylamino)methyl)-6-methoxy-2-(thiophen-3-yl)quinolin-7-ol
   Show/Hide
C23H21BrN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0502961
2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-3-yloxy)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C24H22BrN3O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0506216
2-(4-bromophenyl)-N-((2-(thiophen-3-yl)-7-(trifluoromethoxy)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C23H18BrF3N2OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0507509
2-(4-bromophenyl)-N-((6,7-dimethoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
   Show/Hide
C24H23BrN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0374153
N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]-1-phenylmethanamine
   Show/Hide
C22H20N2OS
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS