Brief Information of the Compound and Protein
Compound Name
2-[3,5-bis(trifluoromethyl)phenyl]-2-[[4-(2-fluorophenyl)pyridin-3-yl]methyl-(furan-2-ylmethyl)amino]acetonitrile
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PubChem ID
CID: 73346390
Canonical SMILES
Fc1ccccc1-c1ccncc1CN(Cc1ccco1)C(C#N)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
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Compound Formula C27H18F7N3O
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 892 nM
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