Brief Information of the Compound and Protein
Compound Name
2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
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PubChem ID
CID: 24969872
SID: 56268019
Canonical SMILES
COc1ccc2cc(CNCCc3ccc(Br)cc3)c(nc2c1)-c1ccsc1
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Compound Formula C23H21BrN2OS
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000386 Flp-In-CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 154 nM
   TI
   LI
   LO
   TS
2
EC50 = 3220 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS